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The map label for this gene is soxA [H]

Identifier: 13475848

GI number: 13475848

Start: 5786582

End: 5787700

Strand: Reverse

Name: soxA [H]

Synonym: mll7022

Alternate gene names: 13475848

Gene position: 5787700-5786582 (Counterclockwise)

Preceding gene: 13475854

Following gene: 13475847

Centisome position: 82.26

GC content: 66.93

Gene sequence:

>1119_bases
ATGGATGTGATCGTGCTGGGCGGTGGATTGATGGGAACGGCTTCGGCCTATTTCCTCGCCCGGCGCGGTGCGCGCGTGAC
GCTGATCGAGCGCAGCCGGGTCGGCACCGGAGCGACCGTCGCTTCCTTCGGCAACATCCGGCGCACGGGGCGTCATCTGT
CCCAGCTTCCGCTGGCCCACCGCTCGCTTGAGCTGTGGCGAGAGGCCGATCGGATGCTGGGCCGTGACGTGGAATTCCGC
GCCACCGGTCATATCCGGCTGATCTTTGATGAAGGTAGTCTTGCCGACATGCGGGCTTATGCCGAGGCGGCGCGACCTTG
GGGGCTTGAACTGGAGGAACTCGGACAGCGCGAAATCTCCTCCCGCTTTCCCGGCCTCGGCCCCGACGCGATCGCCGCGT
CGTTCTCGCCGCATGACGGCAGCGGTAATCCCCGACTGATCGCGCCGGCCTTCGCCGAAGCCGCCCGCAAGCTCGGCGTG
GCGATCGTCGAGGATGCCGAAATCGACACGATCAGGCGCTCGGGGTCCGGGTTCGTTGTCGTATGTTCCAAAGGTACATT
CGCCGCCGAGTGTCTGCTCAATACCGTCGGAGCCTGGGGCGCGCGCATCGCCGCGCAGTTCGGCGAAGAGGTTCCGCTCG
ACGCCTGCGGTCCGCAGATGGGCGTGACCGAGCCACTGCCGCATCGGATTCTGCCGGTGGTGGGCATCTGGACGCGCGAC
AAGGACCATGGCGCCTATCTGCGTCAGGTCGAGCGGGGCAACATCGTCTTCGGCGGCGCGGCCGAAAGGGTACCGGTGGA
CCTCGATCCAGGTCATGCGGTCGCCGATCCCACGCGCCTTCCGCTGCAATTGCGCGCGGTCGCGCGACTGCTGCCGGCAA
TCGCGCAGGTCGCGGTCATCCGCACCTGGTCCGGCTGCGAGGGTTATGTGCGCGACATGCTGCCGGTCATGGGACGCTCG
GCGACAACGCCGGGCCTGTTCCACGCCTTCGGCTTCAGCGGACATGGCTTCCAGCTTGGTCCGGGCGTGGGCGACGCCAT
GGCCGAACTCATCATGACCGGCCGTTGCGAAACACCGCTCGACGATTTCAGGGTTGATCGCTTCGGCCGCGCAGCCTGA

Upstream 100 bases:

>100_bases
GTCAAGCTTATGGCTGTTGTCCAAACCCATCTTTGACGCAATCCTGCGGAGCCGACAAGATCGGCGACTTCAGGATCATT
CGCTCCGCGCAGGAACAACC

Downstream 100 bases:

>100_bases
TCGAGCAACTGACGACATCCGCGCCACGATGGTTCTCTTGGCCGCGAAAGGCGGGATGGTTACTCTCGCATGCGCCTTAG
GGCATGACGATCTCAGGCGA

Product: sarcosine oxidase, subunit beta

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MDVIVLGGGLMGTASAYFLARRGARVTLIERSRVGTGATVASFGNIRRTGRHLSQLPLAHRSLELWREADRMLGRDVEFR
ATGHIRLIFDEGSLADMRAYAEAARPWGLELEELGQREISSRFPGLGPDAIAASFSPHDGSGNPRLIAPAFAEAARKLGV
AIVEDAEIDTIRRSGSGFVVVCSKGTFAAECLLNTVGAWGARIAAQFGEEVPLDACGPQMGVTEPLPHRILPVVGIWTRD
KDHGAYLRQVERGNIVFGGAAERVPVDLDPGHAVADPTRLPLQLRAVARLLPAIAQVAVIRTWSGCEGYVRDMLPVMGRS
ATTPGLFHAFGFSGHGFQLGPGVGDAMAELIMTGRCETPLDDFRVDRFGRAA

Sequences:

>Translated_372_residues
MDVIVLGGGLMGTASAYFLARRGARVTLIERSRVGTGATVASFGNIRRTGRHLSQLPLAHRSLELWREADRMLGRDVEFR
ATGHIRLIFDEGSLADMRAYAEAARPWGLELEELGQREISSRFPGLGPDAIAASFSPHDGSGNPRLIAPAFAEAARKLGV
AIVEDAEIDTIRRSGSGFVVVCSKGTFAAECLLNTVGAWGARIAAQFGEEVPLDACGPQMGVTEPLPHRILPVVGIWTRD
KDHGAYLRQVERGNIVFGGAAERVPVDLDPGHAVADPTRLPLQLRAVARLLPAIAQVAVIRTWSGCEGYVRDMLPVMGRS
ATTPGLFHAFGFSGHGFQLGPGVGDAMAELIMTGRCETPLDDFRVDRFGRAA
>Mature_372_residues
MDVIVLGGGLMGTASAYFLARRGARVTLIERSRVGTGATVASFGNIRRTGRHLSQLPLAHRSLELWREADRMLGRDVEFR
ATGHIRLIFDEGSLADMRAYAEAARPWGLELEELGQREISSRFPGLGPDAIAASFSPHDGSGNPRLIAPAFAEAARKLGV
AIVEDAEIDTIRRSGSGFVVVCSKGTFAAECLLNTVGAWGARIAAQFGEEVPLDACGPQMGVTEPLPHRILPVVGIWTRD
KDHGAYLRQVERGNIVFGGAAERVPVDLDPGHAVADPTRLPLQLRAVARLLPAIAQVAVIRTWSGCEGYVRDMLPVMGRS
ATTPGLFHAFGFSGHGFQLGPGVGDAMAELIMTGRCETPLDDFRVDRFGRAA

Specific function: Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L- alanine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=397, Percent_Identity=26.9521410579345, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI197927446, Length=394, Percent_Identity=25.6345177664975, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21361378, Length=394, Percent_Identity=25.6345177664975, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194306651, Length=384, Percent_Identity=24.21875, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI8923708, Length=399, Percent_Identity=25.31328320802, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787298, Length=391, Percent_Identity=22.5063938618926, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130091, Length=380, Percent_Identity=28.9473684210526, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28571104, Length=390, Percent_Identity=24.1025641025641, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 39898; Mature: 39898

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVIVLGGGLMGTASAYFLARRGARVTLIERSRVGTGATVASFGNIRRTGRHLSQLPLAH
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
RSLELWREADRMLGRDVEFRATGHIRLIFDEGSLADMRAYAEAARPWGLELEELGQREIS
HHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
SRFPGLGPDAIAASFSPHDGSGNPRLIAPAFAEAARKLGVAIVEDAEIDTIRRSGSGFVV
HHCCCCCHHHHEECCCCCCCCCCCCEEEHHHHHHHHHCCEEEEECCCHHHHHCCCCCEEE
VCSKGTFAAECLLNTVGAWGARIAAQFGEEVPLDACGPQMGVTEPLPHRILPVVGIWTRD
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCHHEEEEEEEECC
KDHGAYLRQVERGNIVFGGAAERVPVDLDPGHAVADPTRLPLQLRAVARLLPAIAQVAVI
CCCCHHHHHHCCCCEEECCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RTWSGCEGYVRDMLPVMGRSATTPGLFHAFGFSGHGFQLGPGVGDAMAELIMTGRCETPL
HCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCCCCH
DDFRVDRFGRAA
HHHHHHHCCCCC
>Mature Secondary Structure
MDVIVLGGGLMGTASAYFLARRGARVTLIERSRVGTGATVASFGNIRRTGRHLSQLPLAH
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
RSLELWREADRMLGRDVEFRATGHIRLIFDEGSLADMRAYAEAARPWGLELEELGQREIS
HHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
SRFPGLGPDAIAASFSPHDGSGNPRLIAPAFAEAARKLGVAIVEDAEIDTIRRSGSGFVV
HHCCCCCHHHHEECCCCCCCCCCCCEEEHHHHHHHHHCCEEEEECCCHHHHHCCCCCEEE
VCSKGTFAAECLLNTVGAWGARIAAQFGEEVPLDACGPQMGVTEPLPHRILPVVGIWTRD
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCHHEEEEEEEECC
KDHGAYLRQVERGNIVFGGAAERVPVDLDPGHAVADPTRLPLQLRAVARLLPAIAQVAVI
CCCCHHHHHHCCCCEEECCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RTWSGCEGYVRDMLPVMGRSATTPGLFHAFGFSGHGFQLGPGVGDAMAELIMTGRCETPL
HCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEECCCCHHHHHHHHHCCCCCCCH
DDFRVDRFGRAA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10220347; 10913293; 11087383; 10368302 [H]