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The map label for this gene is tqsA [H]

Identifier: 13475610

GI number: 13475610

Start: 5517691

End: 5518695

Strand: Direct

Name: tqsA [H]

Synonym: mlr6726

Alternate gene names: 13475610

Gene position: 5517691-5518695 (Clockwise)

Preceding gene: 13475609

Following gene: 13475611

Centisome position: 78.42

GC content: 58.31

Gene sequence:

>1005_bases
ATGGTCAACCCTATTGCGACCGGCATCCTCGTTCTCGCTGCGCTGTATTTCGCCAGATCGATTCTCATGCCCCTTGCATT
CTCACTGTTCGTGATTGCGTTGGCATGGCCAATTCAGATGGCTCTGCAGCGGCGGATTCCGCGGTTGGCAGCCTTGCTGA
TCACACTTCTGCTTGTGGTTCTGGTGATCGTAATCGTGGGCTCGGCGATTGTCTGGGGGCTCGGCGAACTATCGCAATGG
CTTTTTTACAATACCGGCCGATTGCAGGCGATCTACGCCAGTTGGACGGACTGGCTGGAGGGCCACGGAATTGCGATCGT
CAGCCCGCTAGGAGAGCTTTTCAGTATATCCCGGCTGGTCGGCCTGACCCACAGCCTCGTCACGCGGCTGAACAGCGTCG
CCGGCTTTGCCGTGTTGACCTTTATTTTCGTGATGCTGGGCCTGTTGGAAGCCGAAGACCTGCAACGTCGCCTGCGGTCA
TCCTTGGCCCAGCCGCAAGGGGAGATGCTGTTGCATATCGGCCGCGAAATTGCCGGCAAAATTCGCCGTTTCATGGTTGT
GCGCAGTCTCGCGTGTATTCTGACGGGCTTGGTCGTGTGGGCTTTTACGCTTGTTGCCGGCCTCGAACTCGCAAGCGCTT
GGGCAGCAATCGCCTTCGCGCTGAACTACATCCCATTCATCGGACCGCTCATGGCCACAATCTTCCCGACCCTGTTTGCC
ATCGCGCAGTCCGGGTCCTGGCAGTTGGCCCTGATTGTGTTCGTCGGCTTGAATGTCATTCAGTTTGCCATTGGCAGCTA
TCTGGAGCCATTTCTGACCGGCGCGTCGCTGGCGATCTCGCCTTTCGCCGTTATGTTCGCGGTGTTTTTCTGGAGCTTCA
TGTGGGGGGTGCCCGGCGCTTTCATCGGCGTGCCGATCCTGATTGTCGTGGTCACATGGTGCGCGCACGAGCAGTCAACA
CGCTGGATCGCAACGTTGCTGTCTGGGGGGCGTCAATCGACCTGA

Upstream 100 bases:

>100_bases
GCATGAGTCTGTGCCGGATTTCCGCATGAGTGAAACAAGATTGCGGCGACCGCGCTCGAGAAACGACAGGGCAAACGTGG
CCGAAACGAGCAACCGCCGT

Downstream 100 bases:

>100_bases
TGTCCATCGGCACTGTTAACTATACCTGACCCATGCAGGGCGAGTGGTTTGGCAATTCAACTTGAATTTCCAGACAATTT
GGTCTAAGTTGGTGCGTGTG

Product: hypothetical protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVNPIATGILVLAALYFARSILMPLAFSLFVIALAWPIQMALQRRIPRLAALLITLLLVVLVIVIVGSAIVWGLGELSQW
LFYNTGRLQAIYASWTDWLEGHGIAIVSPLGELFSISRLVGLTHSLVTRLNSVAGFAVLTFIFVMLGLLEAEDLQRRLRS
SLAQPQGEMLLHIGREIAGKIRRFMVVRSLACILTGLVVWAFTLVAGLELASAWAAIAFALNYIPFIGPLMATIFPTLFA
IAQSGSWQLALIVFVGLNVIQFAIGSYLEPFLTGASLAISPFAVMFAVFFWSFMWGVPGAFIGVPILIVVVTWCAHEQST
RWIATLLSGGRQST

Sequences:

>Translated_334_residues
MVNPIATGILVLAALYFARSILMPLAFSLFVIALAWPIQMALQRRIPRLAALLITLLLVVLVIVIVGSAIVWGLGELSQW
LFYNTGRLQAIYASWTDWLEGHGIAIVSPLGELFSISRLVGLTHSLVTRLNSVAGFAVLTFIFVMLGLLEAEDLQRRLRS
SLAQPQGEMLLHIGREIAGKIRRFMVVRSLACILTGLVVWAFTLVAGLELASAWAAIAFALNYIPFIGPLMATIFPTLFA
IAQSGSWQLALIVFVGLNVIQFAIGSYLEPFLTGASLAISPFAVMFAVFFWSFMWGVPGAFIGVPILIVVVTWCAHEQST
RWIATLLSGGRQST
>Mature_334_residues
MVNPIATGILVLAALYFARSILMPLAFSLFVIALAWPIQMALQRRIPRLAALLITLLLVVLVIVIVGSAIVWGLGELSQW
LFYNTGRLQAIYASWTDWLEGHGIAIVSPLGELFSISRLVGLTHSLVTRLNSVAGFAVLTFIFVMLGLLEAEDLQRRLRS
SLAQPQGEMLLHIGREIAGKIRRFMVVRSLACILTGLVVWAFTLVAGLELASAWAAIAFALNYIPFIGPLMATIFPTLFA
IAQSGSWQLALIVFVGLNVIQFAIGSYLEPFLTGASLAISPFAVMFAVFFWSFMWGVPGAFIGVPILIVVVTWCAHEQST
RWIATLLSGGRQST

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=323, Percent_Identity=28.1733746130031, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082271, Length=221, Percent_Identity=27.1493212669683, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 36448; Mature: 36448

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNPIATGILVLAALYFARSILMPLAFSLFVIALAWPIQMALQRRIPRLAALLITLLLVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIVIVGSAIVWGLGELSQWLFYNTGRLQAIYASWTDWLEGHGIAIVSPLGELFSISRLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
GLTHSLVTRLNSVAGFAVLTFIFVMLGLLEAEDLQRRLRSSLAQPQGEMLLHIGREIAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IRRFMVVRSLACILTGLVVWAFTLVAGLELASAWAAIAFALNYIPFIGPLMATIFPTLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQSGSWQLALIVFVGLNVIQFAIGSYLEPFLTGASLAISPFAVMFAVFFWSFMWGVPGA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
FIGVPILIVVVTWCAHEQSTRWIATLLSGGRQST
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVNPIATGILVLAALYFARSILMPLAFSLFVIALAWPIQMALQRRIPRLAALLITLLLVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIVIVGSAIVWGLGELSQWLFYNTGRLQAIYASWTDWLEGHGIAIVSPLGELFSISRLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
GLTHSLVTRLNSVAGFAVLTFIFVMLGLLEAEDLQRRLRSSLAQPQGEMLLHIGREIAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IRRFMVVRSLACILTGLVVWAFTLVAGLELASAWAAIAFALNYIPFIGPLMATIFPTLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQSGSWQLALIVFVGLNVIQFAIGSYLEPFLTGASLAISPFAVMFAVFFWSFMWGVPGA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
FIGVPILIVVVTWCAHEQSTRWIATLLSGGRQST
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]