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The map label for this gene is phoP [H]

Identifier: 13475585

GI number: 13475585

Start: 5487877

End: 5488269

Strand: Direct

Name: phoP [H]

Synonym: mlr6691

Alternate gene names: 13475585

Gene position: 5487877-5488269 (Clockwise)

Preceding gene: 13475584

Following gene: 13475586

Centisome position: 78.0

GC content: 61.58

Gene sequence:

>393_bases
GTGAATGGAGCGAAGGCAAGAGTTCTGATCTGCGATGATGATCCCCTGTTGCTTGAACTGATGGAATTCAGGCTGAGGGC
GAAGGGATACGAGGTCATCACGGCAGTGGACGGTGCCGAGGCACTGGCGAAGGCGGAACAGCACGGACCCGATATCATCG
TGCTCGATGCGATGATGCCCAAGGCCGACGGCCTGGAGGTGCTGGCTCGCCTCAAGGGCGACCCGGTCCTGTCAGACACG
CCGGTGGTGATGCTGACCGCCCGCAAGGCCGAAAGGGACATCGTCTCGGCCCTCGAGAAGGGAGCCGACGACTATCTGGT
AAAGCCATTCATCCCCGAGGAACTGCTGGCCCGGCTGGCGCGTCTGATCGCGCGCAAGAATGGGAAACGCTGA

Upstream 100 bases:

>100_bases
GAGACCCGCACCGGCGTTGTTTGCATGGATCGCATTGGCGGATGTCGGTTCATGGGTTGATCACTCCGGGGGGCACGAGG
CGTGAACCGGAGCAGCACTG

Downstream 100 bases:

>100_bases
TGAGGCGCAGCCGGCGCGCAGCGCTTGCCGCATGCCTGATCCTGGCAATCGCGGCCACTCCTGGTGCGGTGCTTGCGCAG
ACGGTCGATGAGCTCTACGC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MNGAKARVLICDDDPLLLELMEFRLRAKGYEVITAVDGAEALAKAEQHGPDIIVLDAMMPKADGLEVLARLKGDPVLSDT
PVVMLTARKAERDIVSALEKGADDYLVKPFIPEELLARLARLIARKNGKR

Sequences:

>Translated_130_residues
MNGAKARVLICDDDPLLLELMEFRLRAKGYEVITAVDGAEALAKAEQHGPDIIVLDAMMPKADGLEVLARLKGDPVLSDT
PVVMLTARKAERDIVSALEKGADDYLVKPFIPEELLARLARLIARKNGKR
>Mature_130_residues
MNGAKARVLICDDDPLLLELMEFRLRAKGYEVITAVDGAEALAKAEQHGPDIIVLDAMMPKADGLEVLARLKGDPVLSDT
PVVMLTARKAERDIVSALEKGADDYLVKPFIPEELLARLARLIARKNGKR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=40.3361344537815, Blast_Score=97, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=122, Percent_Identity=37.7049180327869, Blast_Score=88, Evalue=2e-19,
Organism=Escherichia coli, GI1788394, Length=124, Percent_Identity=38.7096774193548, Blast_Score=85, Evalue=2e-18,
Organism=Escherichia coli, GI1790552, Length=123, Percent_Identity=38.2113821138211, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=35.8333333333333, Blast_Score=77, Evalue=5e-16,
Organism=Escherichia coli, GI2367329, Length=121, Percent_Identity=42.9752066115703, Blast_Score=76, Evalue=9e-16,
Organism=Escherichia coli, GI87082012, Length=113, Percent_Identity=38.0530973451327, Blast_Score=72, Evalue=8e-15,
Organism=Escherichia coli, GI1786911, Length=112, Percent_Identity=39.2857142857143, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=36.1344537815126, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI1790863, Length=119, Percent_Identity=31.9327731092437, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=36.1344537815126, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=33.0275229357798, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1789402, Length=128, Percent_Identity=38.28125, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=122, Percent_Identity=31.9672131147541, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=35.2941176470588, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788905, Length=109, Percent_Identity=36.697247706422, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=28.448275862069, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14234; Mature: 14234

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGAKARVLICDDDPLLLELMEFRLRAKGYEVITAVDGAEALAKAEQHGPDIIVLDAMMP
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCC
KADGLEVLARLKGDPVLSDTPVVMLTARKAERDIVSALEKGADDYLVKPFIPEELLARLA
CCCCHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
RLIARKNGKR
HHHHHCCCCC
>Mature Secondary Structure
MNGAKARVLICDDDPLLLELMEFRLRAKGYEVITAVDGAEALAKAEQHGPDIIVLDAMMP
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCC
KADGLEVLARLKGDPVLSDTPVVMLTARKAERDIVSALEKGADDYLVKPFIPEELLARLA
CCCCHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
RLIARKNGKR
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]