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The map label for this gene is agaR [H]

Identifier: 13475543

GI number: 13475543

Start: 5439057

End: 5439773

Strand: Direct

Name: agaR [H]

Synonym: mlr6641

Alternate gene names: 13475543

Gene position: 5439057-5439773 (Clockwise)

Preceding gene: 13475538

Following gene: 13475547

Centisome position: 77.3

GC content: 55.93

Gene sequence:

>717_bases
ATGCTGGCGGGCCATACATTGATCGAAAGCAAAAACGACCACCAAAGCCGCCGCAATTGCGAATTCCGGCGGGCGATTGC
AGCGGCGGGGCGCTGTCGCCGCGTCTATGGCGGAGCACTCCCACTTCTTGCAAGCAGTGTTCCAATGTCAGTCCGAATGG
ACACCCGGCATCGACAAAAACAGGCGCTTGCGCAAACCGCCGCGACAATGATCGAGCCTGGAGAATTCATATTTCTGGAC
AGCGGTAGCACCAATCTGGCGCTGATCGATTTCTTGCCGAAAGGCTACGATCTGACCTTGGCCACCAATTCCATAGATAT
TGCCGGCGCAGCGCTGCGAGGACAGGACCTGAAACTCATTATGCTCGGCGGGACAGTCGATCTTGCTGTCGGCGGTTGCG
TCGATGCCACGGCTATAGGTAGTCTTGCGCAGATGAACATCGACAGATCCTTTATCGGCGTCTGTTCGGTTTCTCCAACA
TTCGGCCTTAGTGCATTCGACATTGCTGACGCTACCTTCAAGCGGGCTCTGGTGGCGGCCAGCGGATATACTATCGCCCT
GGCTACGACGGATAAGCTAGAGGTGAGAGCGCCGCACCGCGTATCCGAGATAAATGAGATCGACTGTCTAGTCCTCGAGC
ACGATGCGCCAATAAGCCATCTCGACGATCTAGTGCGAGCCGGAGCCAGCATTGTAAAAGCCCTTCAGCCTTTCTGA

Upstream 100 bases:

>100_bases
GCGTCTTCTGTCCTCATCCGGCGGCGATTGGGCTAGCCGGCAGACGTCCGGTGCCGGAACGTCCTCTCAACCATACCTGT
CACTTGTGGTCCCTTAAAAT

Downstream 100 bases:

>100_bases
CGCCAACTGCACGGCCTATATTCCATCTGACACCGTCTCGATCCGCTCTTCGGTGAAGCCTGTTGCGCAGCAACGTCAGT
TCAAGCTCGTGCCCAGCACT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLAGHTLIESKNDHQSRRNCEFRRAIAAAGRCRRVYGGALPLLASSVPMSVRMDTRHRQKQALAQTAATMIEPGEFIFLD
SGSTNLALIDFLPKGYDLTLATNSIDIAGAALRGQDLKLIMLGGTVDLAVGGCVDATAIGSLAQMNIDRSFIGVCSVSPT
FGLSAFDIADATFKRALVAASGYTIALATTDKLEVRAPHRVSEINEIDCLVLEHDAPISHLDDLVRAGASIVKALQPF

Sequences:

>Translated_238_residues
MLAGHTLIESKNDHQSRRNCEFRRAIAAAGRCRRVYGGALPLLASSVPMSVRMDTRHRQKQALAQTAATMIEPGEFIFLD
SGSTNLALIDFLPKGYDLTLATNSIDIAGAALRGQDLKLIMLGGTVDLAVGGCVDATAIGSLAQMNIDRSFIGVCSVSPT
FGLSAFDIADATFKRALVAASGYTIALATTDKLEVRAPHRVSEINEIDCLVLEHDAPISHLDDLVRAGASIVKALQPF
>Mature_238_residues
MLAGHTLIESKNDHQSRRNCEFRRAIAAAGRCRRVYGGALPLLASSVPMSVRMDTRHRQKQALAQTAATMIEPGEFIFLD
SGSTNLALIDFLPKGYDLTLATNSIDIAGAALRGQDLKLIMLGGTVDLAVGGCVDATAIGSLAQMNIDRSFIGVCSVSPT
FGLSAFDIADATFKRALVAASGYTIALATTDKLEVRAPHRVSEINEIDCLVLEHDAPISHLDDLVRAGASIVKALQPF

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=205, Percent_Identity=25.8536585365854, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789829, Length=183, Percent_Identity=24.0437158469945, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI226510968, Length=207, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789059, Length=185, Percent_Identity=25.9459459459459, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 25337; Mature: 25337

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGHTLIESKNDHQSRRNCEFRRAIAAAGRCRRVYGGALPLLASSVPMSVRMDTRHRQK
CCCCCCEECCCCCCHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECHHHHHH
QALAQTAATMIEPGEFIFLDSGSTNLALIDFLPKGYDLTLATNSIDIAGAALRGQDLKLI
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCEEEEEEECCEEEEEEEECCCCEEEE
MLGGTVDLAVGGCVDATAIGSLAQMNIDRSFIGVCSVSPTFGLSAFDIADATFKRALVAA
EECCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEE
SGYTIALATTDKLEVRAPHRVSEINEIDCLVLEHDAPISHLDDLVRAGASIVKALQPF
CCCEEEEEECCCEEEECCCHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLAGHTLIESKNDHQSRRNCEFRRAIAAAGRCRRVYGGALPLLASSVPMSVRMDTRHRQK
CCCCCCEECCCCCCHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECHHHHHH
QALAQTAATMIEPGEFIFLDSGSTNLALIDFLPKGYDLTLATNSIDIAGAALRGQDLKLI
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCEEEEEEECCEEEEEEEECCCCEEEE
MLGGTVDLAVGGCVDATAIGSLAQMNIDRSFIGVCSVSPTFGLSAFDIADATFKRALVAA
EECCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEE
SGYTIALATTDKLEVRAPHRVSEINEIDCLVLEHDAPISHLDDLVRAGASIVKALQPF
CCCEEEEEECCCEEEECCCHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]