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The map label for this gene is nccN [H]

Identifier: 13475426

GI number: 13475426

Start: 5299905

End: 5300435

Strand: Direct

Name: nccN [H]

Synonym: mlr6490

Alternate gene names: 13475426

Gene position: 5299905-5300435 (Clockwise)

Preceding gene: 13475424

Following gene: 13475428

Centisome position: 75.32

GC content: 56.31

Gene sequence:

>531_bases
TTGGCGACCGTTATATCCGCCCTGCAGGTTTTCCTGACGGTCGGCCGTCTCCCGCCAAAAGGAACCGCGCAGGGAATCGA
ACCAAGGGTCACTTCTGTCGCCGGAACTTTCCTGATCATCGTTGCAATGTTTGTGACCCCAGCACTGGAAAGCGAGGCAG
CGCAAATGGTGGCGCTGTGCTTGATTTTCATCGGCATGGCGGGCTCCGTGTTTTGCCTGTACTGGCTCGGCCGCTCTTTC
TCCATCATGGCTACGGCCCGGCAGTTGGTTACCTCTGGCCCATATTCCATTGTTCGCCATCCGCTTTACATCTGCGAGGC
GACATTCGTTCTCGGAATGATCCTTTCGCACTTGTCGGTGTTGATGGTGGTGTTAGGCGCGGTCCAATTTCTCGTACAGT
ATCGACGTGCACGGAACGAGGAAGGCATCCTTCGACAGACATTCCCTGAATATGAAGGATACGCTCGGCGCGTCCCAATG
CTTCTGCCGCGGTTCTTTCGTGCAGGGGCAGCGGTTTCCAGACGGTCATAG

Upstream 100 bases:

>100_bases
CTGCATCATGACGGTTCTGGCGGTTCTCAGCGCGATTCCTCTGTTCGCCTATTTCCATCAGAACGCATCGGTAAGTTCGC
TGGCCGTCGTCAACCAGGTC

Downstream 100 bases:

>100_bases
ATCAACGACCTGATGCACTCGTCATGGTGGTCTTCTCGGTGGCAGCCGGAGCGATCAGCTTCTGGCCGCCATTCTCTGAG
CCAAGTCTTGTTGATTTGCG

Product: nickel-cobalt-cadmium resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MATVISALQVFLTVGRLPPKGTAQGIEPRVTSVAGTFLIIVAMFVTPALESEAAQMVALCLIFIGMAGSVFCLYWLGRSF
SIMATARQLVTSGPYSIVRHPLYICEATFVLGMILSHLSVLMVVLGAVQFLVQYRRARNEEGILRQTFPEYEGYARRVPM
LLPRFFRAGAAVSRRS

Sequences:

>Translated_176_residues
MATVISALQVFLTVGRLPPKGTAQGIEPRVTSVAGTFLIIVAMFVTPALESEAAQMVALCLIFIGMAGSVFCLYWLGRSF
SIMATARQLVTSGPYSIVRHPLYICEATFVLGMILSHLSVLMVVLGAVQFLVQYRRARNEEGILRQTFPEYEGYARRVPM
LLPRFFRAGAAVSRRS
>Mature_175_residues
ATVISALQVFLTVGRLPPKGTAQGIEPRVTSVAGTFLIIVAMFVTPALESEAAQMVALCLIFIGMAGSVFCLYWLGRSFS
IMATARQLVTSGPYSIVRHPLYICEATFVLGMILSHLSVLMVVLGAVQFLVQYRRARNEEGILRQTFPEYEGYARRVPML
LPRFFRAGAAVSRRS

Specific function: Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium. Appears to be involved in metal specificity but affects only nickel resistance. May be involved in nickel transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.eutrophus CzcN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 19364; Mature: 19233

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVISALQVFLTVGRLPPKGTAQGIEPRVTSVAGTFLIIVAMFVTPALESEAAQMVALC
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFIGMAGSVFCLYWLGRSFSIMATARQLVTSGPYSIVRHPLYICEATFVLGMILSHLSV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVVLGAVQFLVQYRRARNEEGILRQTFPEYEGYARRVPMLLPRFFRAGAAVSRRS
HHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
ATVISALQVFLTVGRLPPKGTAQGIEPRVTSVAGTFLIIVAMFVTPALESEAAQMVALC
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFIGMAGSVFCLYWLGRSFSIMATARQLVTSGPYSIVRHPLYICEATFVLGMILSHLSV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMVVLGAVQFLVQYRRARNEEGILRQTFPEYEGYARRVPMLLPRFFRAGAAVSRRS
HHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]