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The map label for this gene is ubiE [C]

Identifier: 13475202

GI number: 13475202

Start: 5044983

End: 5045759

Strand: Direct

Name: ubiE [C]

Synonym: mlr6226

Alternate gene names: 13475202

Gene position: 5044983-5045759 (Clockwise)

Preceding gene: 13475195

Following gene: 13475215

Centisome position: 71.7

GC content: 48.91

Gene sequence:

>777_bases
ATGAATGACGAGGTCAGTAAAAACATATCACTGTCCGATTTTGAACCATACTTCAAGGAAGATTACTTTAGAGAGGATTA
CTTTTATTTTGACAATGCGGTCAATTCTCCAGAAACGAGTGATCGACAAGCAGGGGTAATTTGGAACCTGCTTTCCCTTG
GGCAAGGCAGCTCAGTTCTTGAACTTGGATGCGGCTATGGGCGGATTACAAACCGGTTGGCAAAAAAAGGAGCGCATGTA
GTCGGGCTTGATATCTCACCGATCTTGCTAAAAGAAGCCGAAACGGATGCGGCTGAACGTGGAGTAAAGGTTGAGTATGT
CCTCGGCGACATGCGCTCACTTCCTTGGCGAGATCGATTCGACGCGGCTTTTCTGTGGTACACCACGTTTGGCTATTTCG
ATGACGCGGACAATGAGAGAGTTCTTCGTGAAGCCGCTTCTTCACTTCGAAAGGGTGGGCGTCTGCTAATCGATCACCCC
AATCGCATCGATTTCCTGCGCCACAAGTCGCCTGTCTGTTACGTTACGCAGCGTAACAACGATGTAAGGATCGATATGTT
TAGCAACGATGTGCTAAGCGATCGCTCGAACCTCGAAAGGCTTATCGTCCGTGATGGATGCGTTAGACGAACGCACCTTT
CTTTCAGACAGTATGGGGTCTCTGAGTATGTTCGCATGTTGCGAAGTGCCGGGTTCGAGACCGTTGAAGCTTATGGGCAG
GAAGGTGAAGCGTTTACATCAGATAGCTCGCGCCTCGTGGTTGTCGCATGCAAATAA

Upstream 100 bases:

>100_bases
TTAACAACGGTATGAAAATTTTCACAAATGTTTTCTTTCAATATTACCCGCCGTATGCAAAAATCGCTATAAATTGTAAG
CTCATCATGAGGGCAGACAC

Downstream 100 bases:

>100_bases
TACCAGCGGCCATGGGACAAGCTCCTGCTGATTATTTTCCGGACATGTCGCCCCGGGGGTCACTCGCTTCTGTCCGATAA
ATCGTCGGAATCTGCATCGA

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; D-Alanine-D-Alanine Ligase Related Protein; Methyltransferase Family Protein; L-Glutaminyl-2-N-Methyltransferase StsG; D-Alanine-D-Alanine Ligase; Menaquinone Biosynthesis Methlytransferase ; L-Glutaminyl-2-N-Methyltransferase; Cyclopropane-Fatty-Acyl-Phospholipid Synthase Superfamily; Methyltransferase Domain Family; SAM-Dependent Methyltransferase UbiE/COQ5 Family; UbiE/COQ5-Like Methyltransferase

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNDEVSKNISLSDFEPYFKEDYFREDYFYFDNAVNSPETSDRQAGVIWNLLSLGQGSSVLELGCGYGRITNRLAKKGAHV
VGLDISPILLKEAETDAAERGVKVEYVLGDMRSLPWRDRFDAAFLWYTTFGYFDDADNERVLREAASSLRKGGRLLIDHP
NRIDFLRHKSPVCYVTQRNNDVRIDMFSNDVLSDRSNLERLIVRDGCVRRTHLSFRQYGVSEYVRMLRSAGFETVEAYGQ
EGEAFTSDSSRLVVVACK

Sequences:

>Translated_258_residues
MNDEVSKNISLSDFEPYFKEDYFREDYFYFDNAVNSPETSDRQAGVIWNLLSLGQGSSVLELGCGYGRITNRLAKKGAHV
VGLDISPILLKEAETDAAERGVKVEYVLGDMRSLPWRDRFDAAFLWYTTFGYFDDADNERVLREAASSLRKGGRLLIDHP
NRIDFLRHKSPVCYVTQRNNDVRIDMFSNDVLSDRSNLERLIVRDGCVRRTHLSFRQYGVSEYVRMLRSAGFETVEAYGQ
EGEAFTSDSSRLVVVACK
>Mature_258_residues
MNDEVSKNISLSDFEPYFKEDYFREDYFYFDNAVNSPETSDRQAGVIWNLLSLGQGSSVLELGCGYGRITNRLAKKGAHV
VGLDISPILLKEAETDAAERGVKVEYVLGDMRSLPWRDRFDAAFLWYTTFGYFDDADNERVLREAASSLRKGGRLLIDHP
NRIDFLRHKSPVCYVTQRNNDVRIDMFSNDVLSDRSNLERLIVRDGCVRRTHLSFRQYGVSEYVRMLRSAGFETVEAYGQ
EGEAFTSDSSRLVVVACK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29493; Mature: 29493

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDEVSKNISLSDFEPYFKEDYFREDYFYFDNAVNSPETSDRQAGVIWNLLSLGQGSSVL
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEE
ELGCGYGRITNRLAKKGAHVVGLDISPILLKEAETDAAERGVKVEYVLGDMRSLPWRDRF
EECCCHHHHHHHHHHCCCEEEECCCCHHEEECCCCHHHHCCCEEEEEECHHHCCCCCCCC
DAAFLWYTTFGYFDDADNERVLREAASSLRKGGRLLIDHPNRIDFLRHKSPVCYVTQRNN
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHCCCCEEEEEECCC
DVRIDMFSNDVLSDRSNLERLIVRDGCVRRTHLSFRQYGVSEYVRMLRSAGFETVEAYGQ
EEEEEEECCCHHHCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCC
EGEAFTSDSSRLVVVACK
CCCEEECCCCCEEEEEEC
>Mature Secondary Structure
MNDEVSKNISLSDFEPYFKEDYFREDYFYFDNAVNSPETSDRQAGVIWNLLSLGQGSSVL
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEE
ELGCGYGRITNRLAKKGAHVVGLDISPILLKEAETDAAERGVKVEYVLGDMRSLPWRDRF
EECCCHHHHHHHHHHCCCEEEECCCCHHEEECCCCHHHHCCCEEEEEECHHHCCCCCCCC
DAAFLWYTTFGYFDDADNERVLREAASSLRKGGRLLIDHPNRIDFLRHKSPVCYVTQRNN
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHCCCCEEEEEECCC
DVRIDMFSNDVLSDRSNLERLIVRDGCVRRTHLSFRQYGVSEYVRMLRSAGFETVEAYGQ
EEEEEEECCCHHHCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCC
EGEAFTSDSSRLVVVACK
CCCEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA