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The map label for this gene is slt [C]

Identifier: 13475171

GI number: 13475171

Start: 5008819

End: 5009502

Strand: Direct

Name: slt [C]

Synonym: mlr6189

Alternate gene names: 13475171

Gene position: 5008819-5009502 (Clockwise)

Preceding gene: 13475170

Following gene: 13475172

Centisome position: 71.19

GC content: 61.84

Gene sequence:

>684_bases
ATGGACCGAGTGACCCTCCTGATGCTCGGCATGATCGCCGTCGCGCCATGCGCCTGTTCCGCCTCGACCGGCGCTGAGCC
AGCCGTCATCTCCCAAAGTCCGCAGCTGCAACGATGGCAGCACTTCGTATCGGAAGCAAGCGCACGCTTCCACATTCCCC
AGGCCTGGATTTGCGCCGTCATCGATGCCGAAAGCCGCGGCAAGACCGTCCTCGATGGCCGTCCCATCACCTCCCGCGCC
GGCGCCATGGGTCTTATGCAGGTGATGCCCGGCACCTATCAGGAGATGCGCGTCGAGCACGGTCTGGGAGCCGACCCGCA
CGATCCGCGCGACAACATCTTGGCCGGAACCGCCTATCTCAGCGCCATGTATAAGCGTTTCGGATTCCCCGGCCTGTTTG
CCGCCTACAACGCTGGACCCGAGCGCTATGAAGGCCATTTGAAGCTTCGAAGGCCGCTGCCGAAAGAGACCGTTGCCTAT
CTGAAACAGCTTGAGGCGACGGGGATTTCGGCGGCCGACATGAACGAATTCAAAGGCCAATCCACAACTTCAAAGGGGCG
GAACGCTCCCTCCGGACGCTCTTTGTTCTTCCTTCGCGACGGTGTTCGCGCCGGTGAAACGAATGGCGGCCTTTTCGTGC
CGCTCGGCAGGGATCGCGCGCGGAAAAAGAAGCACAATGGCTAG

Upstream 100 bases:

>100_bases
ACGAGGTTTTCCTGCTCGGCAACGAAAAAAATCACTCCTTCGACAGTCGCTATTTCGGGCCGGTGCCGGCCGAAAACATC
ATCGGGAGGCTGGTGCCGCT

Downstream 100 bases:

>100_bases
CGATGTTGAGGGCATCCGGGAGGGGCCAGGGACGCTTAAGGCGAGGGGCGCGTAATGCCGCCCGTAATCGGGGCGGGCGC
CTGAAAGGGCAGCAAAGCTG

Product: transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Lytic Transglycosylase; Transglycosylase; Murein Transglycosylase; Transglycosylase SLT Family Protein; Soluble Lytic Murein Transglycosylase; Lytic Murein Transglycosylase; Transglycosylase SLT Domain Protein; Soluble Lytic Transglycosylase

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDRVTLLMLGMIAVAPCACSASTGAEPAVISQSPQLQRWQHFVSEASARFHIPQAWICAVIDAESRGKTVLDGRPITSRA
GAMGLMQVMPGTYQEMRVEHGLGADPHDPRDNILAGTAYLSAMYKRFGFPGLFAAYNAGPERYEGHLKLRRPLPKETVAY
LKQLEATGISAADMNEFKGQSTTSKGRNAPSGRSLFFLRDGVRAGETNGGLFVPLGRDRARKKKHNG

Sequences:

>Translated_227_residues
MDRVTLLMLGMIAVAPCACSASTGAEPAVISQSPQLQRWQHFVSEASARFHIPQAWICAVIDAESRGKTVLDGRPITSRA
GAMGLMQVMPGTYQEMRVEHGLGADPHDPRDNILAGTAYLSAMYKRFGFPGLFAAYNAGPERYEGHLKLRRPLPKETVAY
LKQLEATGISAADMNEFKGQSTTSKGRNAPSGRSLFFLRDGVRAGETNGGLFVPLGRDRARKKKHNG
>Mature_227_residues
MDRVTLLMLGMIAVAPCACSASTGAEPAVISQSPQLQRWQHFVSEASARFHIPQAWICAVIDAESRGKTVLDGRPITSRA
GAMGLMQVMPGTYQEMRVEHGLGADPHDPRDNILAGTAYLSAMYKRFGFPGLFAAYNAGPERYEGHLKLRRPLPKETVAY
LKQLEATGISAADMNEFKGQSTTSKGRNAPSGRSLFFLRDGVRAGETNGGLFVPLGRDRARKKKHNG

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 24676; Mature: 24676

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVTLLMLGMIAVAPCACSASTGAEPAVISQSPQLQRWQHFVSEASARFHIPQAWICAV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCEECCCHHHEEEE
IDAESRGKTVLDGRPITSRAGAMGLMQVMPGTYQEMRVEHGLGADPHDPRDNILAGTAYL
EECCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHH
SAMYKRFGFPGLFAAYNAGPERYEGHLKLRRPLPKETVAYLKQLEATGISAADMNEFKGQ
HHHHHHHCCCHHHHHHCCCHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCC
STTSKGRNAPSGRSLFFLRDGVRAGETNGGLFVPLGRDRARKKKHNG
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHCCCC
>Mature Secondary Structure
MDRVTLLMLGMIAVAPCACSASTGAEPAVISQSPQLQRWQHFVSEASARFHIPQAWICAV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCEECCCHHHEEEE
IDAESRGKTVLDGRPITSRAGAMGLMQVMPGTYQEMRVEHGLGADPHDPRDNILAGTAYL
EECCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHH
SAMYKRFGFPGLFAAYNAGPERYEGHLKLRRPLPKETVAYLKQLEATGISAADMNEFKGQ
HHHHHHHCCCHHHHHHCCCHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCC
STTSKGRNAPSGRSLFFLRDGVRAGETNGGLFVPLGRDRARKKKHNG
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA