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The map label for this gene is gabD [H]

Identifier: 13475142

GI number: 13475142

Start: 4977512

End: 4977823

Strand: Reverse

Name: gabD [H]

Synonym: mll6153

Alternate gene names: 13475142

Gene position: 4977823-4977512 (Counterclockwise)

Preceding gene: 13475155

Following gene: 13475141

Centisome position: 70.75

GC content: 63.46

Gene sequence:

>312_bases
GTGTTGGCAGAGCTACCCGACATGGGCGCTGAGACGAGCACGGCGATCGACGAGGCTTATACGGCCCAGGCTGGATGGGC
GGCGTTGACCGCCCGGGATCGCAGGGACATGCTCTGGCGCTGGCATCAATTGATCATCGACCACGCCGCCGACCTCGCTG
CCATCCTCACAGCTGAGATGGGCAAGCCGCTTGCCGAAGCCAAGTCGGAGGTCTCGCATGCGGCGGCATATCTGCAATGG
TATGCCAAAGAGGCCAACCGCATCTATGGCGAGACGATCTCCCCGCCCTCGACCGACCGGGAATGCTGGTGA

Upstream 100 bases:

>100_bases
CTGAAATCTGCATAGCTGTTCGTCTCTATGGACGCATGCCGGCACTCGGCACGCCGCCTGGCGAGCGAACTTTCGAGGGC
TTGATCCATCCACTGGCGAA

Downstream 100 bases:

>100_bases
TCAAGCAGCCAGCCGGCGTTGTTGGCACGATCACGCTATGGAATTTCCCGGCTTCAATGGTGGCGCGCAAGATCTCACCG
GCGCTGGCGGCGGCTGCACC

Product: succinic semialdehyde dehydrogenase

Products: NA

Alternate protein names: SSDH [H]

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MLAELPDMGAETSTAIDEAYTAQAGWAALTARDRRDMLWRWHQLIIDHAADLAAILTAEMGKPLAEAKSEVSHAAAYLQW
YAKEANRIYGETISPPSTDRECW

Sequences:

>Translated_103_residues
MLAELPDMGAETSTAIDEAYTAQAGWAALTARDRRDMLWRWHQLIIDHAADLAAILTAEMGKPLAEAKSEVSHAAAYLQW
YAKEANRIYGETISPPSTDRECW
>Mature_103_residues
MLAELPDMGAETSTAIDEAYTAQAGWAALTARDRRDMLWRWHQLIIDHAADLAAILTAEMGKPLAEAKSEVSHAAAYLQW
YAKEANRIYGETISPPSTDRECW

Specific function: Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777721, Length=75, Percent_Identity=44, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI4507229, Length=75, Percent_Identity=44, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789015, Length=100, Percent_Identity=49, Blast_Score=100, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17534119, Length=91, Percent_Identity=36.2637362637363, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319478, Length=96, Percent_Identity=40.625, Blast_Score=78, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362580, Length=104, Percent_Identity=43.2692307692308, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI62472918, Length=104, Percent_Identity=43.2692307692308, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI62472926, Length=104, Percent_Identity=43.2692307692308, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI62472936, Length=104, Percent_Identity=43.2692307692308, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356737, Length=104, Percent_Identity=43.2692307692308, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010102 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.79 [H]

Molecular weight: Translated: 11478; Mature: 11478

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAELPDMGAETSTAIDEAYTAQAGWAALTARDRRDMLWRWHQLIIDHAADLAAILTAEM
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKPLAEAKSEVSHAAAYLQWYAKEANRIYGETISPPSTDRECW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLAELPDMGAETSTAIDEAYTAQAGWAALTARDRRDMLWRWHQLIIDHAADLAAILTAEM
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKPLAEAKSEVSHAAAYLQWYAKEANRIYGETISPPSTDRECW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]