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The map label for this gene is lysK

Identifier: 13474689

GI number: 13474689

Start: 4525868

End: 4527514

Strand: Reverse

Name: lysK

Synonym: mll5634

Alternate gene names: 13474689

Gene position: 4527514-4525868 (Counterclockwise)

Preceding gene: 13474691

Following gene: 13474680

Centisome position: 64.35

GC content: 62.9

Gene sequence:

>1647_bases
ATGGCGGGATCAAACACAATCGATCTCAACCCCGAGCTGCTGGCGGCTGCGGCCGAAAGCAAGGCATGGCCGTTCGAGGA
AGCCAAAAAGATCATCGAGCGTTACAAAGGCGGCGAGTTTCCCGAAACGATCCTGTTCGAGACCGGCTACGGTCCATCGG
GCCTGCCGCATATCGGCACGTTCGGCGAGGTGGCGCGCACCTCGATGGTGCGCCACGCGTTCCGCGTGCTGACGCAGGAC
AAGGTCGCCACCAAGCTGCTGTGCTTCTCCGACGACATGGACGGGATGCGCAAGATCCCCGACAATGTGCCGGATCGCGC
GGCACTCGAGCCGCACCTGCATAAGCCGCTCTCATCGGTTCCCAATCCGTTCGGCGGCGACTATGCGAGCTTCGCCGATC
ACAACAATGCGATGCTCTGCCGCTTCCTCGACACGTTCGGCTTCGACTACGAATTCGCCAGCGCGACGCAGTATTACAAG
TCGGGCCGTTTCGACGCGATGCTGCTGCGGGCCGCCGAACGCTACGACAAGATCATGGCGGTGATGCTGCCGACGCTCGG
GCCGGAGCGGCAGGCGACCTACAGTCCGTTCCTGCCGATTTCCCCGAAGAGCGGCCGGGTGCTCTACGTGCCGATGAAGC
ATGTCGATGCCAAGGCCGGCACCATCACTTTCGACGATGAAGGCACCGAGACCACGCTTTCGATCACCGGCGGCCGGGTG
AAGCTGCAGTGGAAGCCGGATTTCGGCATGCGCTGGGCGGCGCTCGGCGTCGATTTCGAGATGTTCGGCAAGGACCACCA
GACCAACGCGGTGGTCTATGATCGCATCTGCAACATATTGGGCGGGCGCGCGCCGGAGCATTTCGTCTACGAACTGTTCC
TCGACGAAAACGGCCAGAAGATCTCGAAGTCAAAGGGCAACGGCCTGACCATCGACGAGTGGCTGACCTATGCGCCGACC
GAAAGTCTCGGGCTCTACATGTACCAGCGGCCGCGGCAGGCCAAGAAGCTCTATTTCGACGTCATTCCGAGGGCGGTGGA
CGAGTATTACACCTTCCTGGGCGCCTACCCCAGGCAGGACTGGAAGGAGCGGCTGGGCAATCCTGTCTGGCACATGCATG
ACGGCAACCCGCCAGCAATCGACATGCCGGTGCCGTTCTCGCTGCTGCTCAACCTGGTCAGCGCCTCCAATGCGCAGAAC
AAGGATGTGCTGTGGGGCTTCATCTCGCGCCATACGCAAGGCGTGACGCCAAAGACGCATCCTGAGCTCGACCAATTGGT
CGGCCACGCGATCCGCTATTTCGACGATTTCGTGCGGCCGACGAAGACCTTCCGTGCGGCAGACGAGGTCGAGCGCGAGG
CGCTCGAAGCCCTGGACGCGGCGCTTGGTGCATTGCCGGCGGATGCCGGCGGCGAAGCGATCCAGAACGCTTCGCTCAAC
GTGGCGCGCAAGATCGAACGCTATCAGGATCATTCCAAGCAGAGCCCGGAGGGTGGCCCGGGCGTTTCGGGCGCCTTCTT
CCAGATGATCTACCAGGTGCTTATCGGCCAGGAACGCGGCCCGCGCTTCGGCTCGTTCGCCGCGCTCTACGGCGTCGCCG
AGACCCGCGCGCTCATTCAGCAGGCGCTGGCTGGTCAGCTGGCTTGA

Upstream 100 bases:

>100_bases
GACGCTCCGGCCATGCGCGCCTAGAGGACCGGTTGAAAATCGACACTGCGGCCATGCCATCGAAACAATCTGGCCGGCGA
ACAATTTGGAAAACAGGACC

Downstream 100 bases:

>100_bases
GGGCGCCGTCGACCTCCTCCAGGATCGAACCCGGCGCCTGAGGCGCCGGGGCTGGCGCGGGCGGCACCGCTGATATGCCG
CCAAGGTTCGGCGCCGGTCC

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MAGSNTIDLNPELLAAAAESKAWPFEEAKKIIERYKGGEFPETILFETGYGPSGLPHIGTFGEVARTSMVRHAFRVLTQD
KVATKLLCFSDDMDGMRKIPDNVPDRAALEPHLHKPLSSVPNPFGGDYASFADHNNAMLCRFLDTFGFDYEFASATQYYK
SGRFDAMLLRAAERYDKIMAVMLPTLGPERQATYSPFLPISPKSGRVLYVPMKHVDAKAGTITFDDEGTETTLSITGGRV
KLQWKPDFGMRWAALGVDFEMFGKDHQTNAVVYDRICNILGGRAPEHFVYELFLDENGQKISKSKGNGLTIDEWLTYAPT
ESLGLYMYQRPRQAKKLYFDVIPRAVDEYYTFLGAYPRQDWKERLGNPVWHMHDGNPPAIDMPVPFSLLLNLVSASNAQN
KDVLWGFISRHTQGVTPKTHPELDQLVGHAIRYFDDFVRPTKTFRAADEVEREALEALDAALGALPADAGGEAIQNASLN
VARKIERYQDHSKQSPEGGPGVSGAFFQMIYQVLIGQERGPRFGSFAALYGVAETRALIQQALAGQLA

Sequences:

>Translated_548_residues
MAGSNTIDLNPELLAAAAESKAWPFEEAKKIIERYKGGEFPETILFETGYGPSGLPHIGTFGEVARTSMVRHAFRVLTQD
KVATKLLCFSDDMDGMRKIPDNVPDRAALEPHLHKPLSSVPNPFGGDYASFADHNNAMLCRFLDTFGFDYEFASATQYYK
SGRFDAMLLRAAERYDKIMAVMLPTLGPERQATYSPFLPISPKSGRVLYVPMKHVDAKAGTITFDDEGTETTLSITGGRV
KLQWKPDFGMRWAALGVDFEMFGKDHQTNAVVYDRICNILGGRAPEHFVYELFLDENGQKISKSKGNGLTIDEWLTYAPT
ESLGLYMYQRPRQAKKLYFDVIPRAVDEYYTFLGAYPRQDWKERLGNPVWHMHDGNPPAIDMPVPFSLLLNLVSASNAQN
KDVLWGFISRHTQGVTPKTHPELDQLVGHAIRYFDDFVRPTKTFRAADEVEREALEALDAALGALPADAGGEAIQNASLN
VARKIERYQDHSKQSPEGGPGVSGAFFQMIYQVLIGQERGPRFGSFAALYGVAETRALIQQALAGQLA
>Mature_547_residues
AGSNTIDLNPELLAAAAESKAWPFEEAKKIIERYKGGEFPETILFETGYGPSGLPHIGTFGEVARTSMVRHAFRVLTQDK
VATKLLCFSDDMDGMRKIPDNVPDRAALEPHLHKPLSSVPNPFGGDYASFADHNNAMLCRFLDTFGFDYEFASATQYYKS
GRFDAMLLRAAERYDKIMAVMLPTLGPERQATYSPFLPISPKSGRVLYVPMKHVDAKAGTITFDDEGTETTLSITGGRVK
LQWKPDFGMRWAALGVDFEMFGKDHQTNAVVYDRICNILGGRAPEHFVYELFLDENGQKISKSKGNGLTIDEWLTYAPTE
SLGLYMYQRPRQAKKLYFDVIPRAVDEYYTFLGAYPRQDWKERLGNPVWHMHDGNPPAIDMPVPFSLLLNLVSASNAQNK
DVLWGFISRHTQGVTPKTHPELDQLVGHAIRYFDDFVRPTKTFRAADEVEREALEALDAALGALPADAGGEAIQNASLNV
ARKIERYQDHSKQSPEGGPGVSGAFFQMIYQVLIGQERGPRFGSFAALYGVAETRALIQQALAGQLA

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYK_RHILO (Q98BC8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_106258.1
- ProteinModelPortal:   Q98BC8
- GeneID:   1228919
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5634
- NMPDR:   fig|266835.1.peg.4362
- HOGENOM:   HBG294650
- OMA:   SKGNGLT
- ProtClustDB:   PRK00750
- BRENDA:   6.1.1.6
- GO:   GO:0005737
- HAMAP:   MF_00177
- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- Gene3D:   G3DSA:1.10.10.350
- TIGRFAMs:   TIGR00467

Pfam domain/function: PF01921 tRNA-synt_1f; SSF48163 tRNA-synt_bind

EC number: =6.1.1.6

Molecular weight: Translated: 61015; Mature: 60884

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 303-303

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSNTIDLNPELLAAAAESKAWPFEEAKKIIERYKGGEFPETILFETGYGPSGLPHIGT
CCCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
FGEVARTSMVRHAFRVLTQDKVATKLLCFSDDMDGMRKIPDNVPDRAALEPHLHKPLSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCCCCCCCCCCHHHCHHHHC
PNPFGGDYASFADHNNAMLCRFLDTFGFDYEFASATQYYKSGRFDAMLLRAAERYDKIMA
CCCCCCCHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VMLPTLGPERQATYSPFLPISPKSGRVLYVPMKHVDAKAGTITFDDEGTETTLSITGGRV
HHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEECCCCCEEEEEEECCEE
KLQWKPDFGMRWAALGVDFEMFGKDHQTNAVVYDRICNILGGRAPEHFVYELFLDENGQK
EEEECCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHCCCCCHHEEEEEEECCCCCE
ISKSKGNGLTIDEWLTYAPTESLGLYMYQRPRQAKKLYFDVIPRAVDEYYTFLGAYPRQD
ECCCCCCCCCHHHHHCCCCCCHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
WKERLGNPVWHMHDGNPPAIDMPVPFSLLLNLVSASNAQNKDVLWGFISRHTQGVTPKTH
HHHHHCCCEEEEECCCCCEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCC
PELDQLVGHAIRYFDDFVRPTKTFRAADEVEREALEALDAALGALPADAGGEAIQNASLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHH
VARKIERYQDHSKQSPEGGPGVSGAFFQMIYQVLIGQERGPRFGSFAALYGVAETRALIQ
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
QALAGQLA
HHHHCCCC
>Mature Secondary Structure 
AGSNTIDLNPELLAAAAESKAWPFEEAKKIIERYKGGEFPETILFETGYGPSGLPHIGT
CCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
FGEVARTSMVRHAFRVLTQDKVATKLLCFSDDMDGMRKIPDNVPDRAALEPHLHKPLSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCCCCCCCCCCHHHCHHHHC
PNPFGGDYASFADHNNAMLCRFLDTFGFDYEFASATQYYKSGRFDAMLLRAAERYDKIMA
CCCCCCCHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VMLPTLGPERQATYSPFLPISPKSGRVLYVPMKHVDAKAGTITFDDEGTETTLSITGGRV
HHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEECCCCCEEEEEEECCEE
KLQWKPDFGMRWAALGVDFEMFGKDHQTNAVVYDRICNILGGRAPEHFVYELFLDENGQK
EEEECCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHCCCCCHHEEEEEEECCCCCE
ISKSKGNGLTIDEWLTYAPTESLGLYMYQRPRQAKKLYFDVIPRAVDEYYTFLGAYPRQD
ECCCCCCCCCHHHHHCCCCCCHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
WKERLGNPVWHMHDGNPPAIDMPVPFSLLLNLVSASNAQNKDVLWGFISRHTQGVTPKTH
HHHHHCCCEEEEECCCCCEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCC
PELDQLVGHAIRYFDDFVRPTKTFRAADEVEREALEALDAALGALPADAGGEAIQNASLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHH
VARKIERYQDHSKQSPEGGPGVSGAFFQMIYQVLIGQERGPRFGSFAALYGVAETRALIQ
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
QALAGQLA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968