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The map label for this gene is tlyC [H]

Identifier: 13474617

GI number: 13474617

Start: 4445485

End: 4446561

Strand: Direct

Name: tlyC [H]

Synonym: mlr5537

Alternate gene names: 13474617

Gene position: 4445485-4446561 (Clockwise)

Preceding gene: 13474616

Following gene: 13474618

Centisome position: 63.18

GC content: 64.35

Gene sequence:

>1077_bases
ATGAACGACACACCAGAAACTGCCGCCCGCCCCGACGCCGGCAGTGCGCCCAAGGCTTCCGATACGTCGGAAGAGGGATC
AAGTCCGAGTACCGTTACCGGCAGTGCAGCCAGCGAGCTTTCGCCTGCCGGACCCTCCCTGTTCGACCGTGTTTTGGGCC
TGTTCAGGCAACGCAACGGCACCAGCCTGCGTGAGGAAATCGCCGGCGCGCTGGCCGAGACGGCGAGCGACGCCGAATCC
TTCTCGCCTGGCGAACGCGCCATGCTCAACAACATCCTGCGGCTGCGCGAAGTGCGCGTCGAGGATGTCATGGTGCCGCG
CGCCGATATCGAAGCGGTCGAGATCACCACAACGCTTGGCGATCTCCTGGGCACTTTCGAGCAATCCGGCCATTCCCGCA
TGCCGGTCTATTCCGAGACGCTCGATGACCCGCGCGGCATGGTCCATATCCGTGATGTGCTGGCCCACATCACCAAGCTC
GCGCGCGTCAAAAAGGGGCGCACGACCAGGAAGACGCCCGTAGCCACGCAGCTCGATCTTGCCCAGGTCGACCTCGCGCG
CACCATCGGCGAGCTCAATCTGATCCGCCAGGTTCTGTTCGTGCCGCCCTCGATGCTTGCTTCCGACTTGATGGGCCGCA
TGCAGACGACGCGTACGCAGATGGCGCTGGTCATCGACGAATATGGCGGCACCGACGGCCTTGTCTCGCTCGAGGACATT
GTCGAAATGGTCGTCGGCGACATCGAGGACGAGCATGACGACGACGAACCGATGATCACCCAGGCCGGTGACGGCGTCTT
CATCGTCGACGGCAAGGCCGAGATCGACGAGGTCGCCAAGATGATCGGCGAGGATTTCGCCGCCGGCGAACATGGCGAAT
ATGTCGACACGATCGGCGGCATGATCTTCAACACGCTTGGCCGCGTGCCGGCGCGGGGCGAGGTGGTACAGGCCATTCCA
GGCTTCGAATTCCATGTGCTCGATGCCGATCCGCGCCGCGTCAAGCGCGTGCGCATCGTGCAAAGCCAGAAGGGCGAGCG
CCGCCGGCGCGCCACGGCGCGCACCGAACAGGCCTGA

Upstream 100 bases:

>100_bases
CGAGGCCGAGGCGATGGAGGCGATCGAACGCGCAGCGCTCGCAAGGCTTGCCATTCCCGATCCCTACGCGTAACTACATC
TGACAATTGACCGGACGACG

Downstream 100 bases:

>100_bases
GTTTCCGCTGCCGATGACGGTGGACGACCCATTCAAGCATTCAAGTCTGGGTTCCGGCGTATTTTACAGAAATCCTCGTG
CCGCGCTGGTGTGGCTCGAA

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNDTPETAARPDAGSAPKASDTSEEGSSPSTVTGSAASELSPAGPSLFDRVLGLFRQRNGTSLREEIAGALAETASDAES
FSPGERAMLNNILRLREVRVEDVMVPRADIEAVEITTTLGDLLGTFEQSGHSRMPVYSETLDDPRGMVHIRDVLAHITKL
ARVKKGRTTRKTPVATQLDLAQVDLARTIGELNLIRQVLFVPPSMLASDLMGRMQTTRTQMALVIDEYGGTDGLVSLEDI
VEMVVGDIEDEHDDDEPMITQAGDGVFIVDGKAEIDEVAKMIGEDFAAGEHGEYVDTIGGMIFNTLGRVPARGEVVQAIP
GFEFHVLDADPRRVKRVRIVQSQKGERRRRATARTEQA

Sequences:

>Translated_358_residues
MNDTPETAARPDAGSAPKASDTSEEGSSPSTVTGSAASELSPAGPSLFDRVLGLFRQRNGTSLREEIAGALAETASDAES
FSPGERAMLNNILRLREVRVEDVMVPRADIEAVEITTTLGDLLGTFEQSGHSRMPVYSETLDDPRGMVHIRDVLAHITKL
ARVKKGRTTRKTPVATQLDLAQVDLARTIGELNLIRQVLFVPPSMLASDLMGRMQTTRTQMALVIDEYGGTDGLVSLEDI
VEMVVGDIEDEHDDDEPMITQAGDGVFIVDGKAEIDEVAKMIGEDFAAGEHGEYVDTIGGMIFNTLGRVPARGEVVQAIP
GFEFHVLDADPRRVKRVRIVQSQKGERRRRATARTEQA
>Mature_358_residues
MNDTPETAARPDAGSAPKASDTSEEGSSPSTVTGSAASELSPAGPSLFDRVLGLFRQRNGTSLREEIAGALAETASDAES
FSPGERAMLNNILRLREVRVEDVMVPRADIEAVEITTTLGDLLGTFEQSGHSRMPVYSETLDDPRGMVHIRDVLAHITKL
ARVKKGRTTRKTPVATQLDLAQVDLARTIGELNLIRQVLFVPPSMLASDLMGRMQTTRTQMALVIDEYGGTDGLVSLEDI
VEMVVGDIEDEHDDDEPMITQAGDGVFIVDGKAEIDEVAKMIGEDFAAGEHGEYVDTIGGMIFNTLGRVPARGEVVQAIP
GFEFHVLDADPRRVKRVRIVQSQKGERRRRATARTEQA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=255, Percent_Identity=26.2745098039216, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786879, Length=255, Percent_Identity=30.9803921568627, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082033, Length=282, Percent_Identity=26.5957446808511, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693175, Length=282, Percent_Identity=26.241134751773, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790664, Length=270, Percent_Identity=23.3333333333333, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788119, Length=264, Percent_Identity=23.4848484848485, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 38852; Mature: 38852

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTPETAARPDAGSAPKASDTSEEGSSPSTVTGSAASELSPAGPSLFDRVLGLFRQRNG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
TSLREEIAGALAETASDAESFSPGERAMLNNILRLREVRVEDVMVPRADIEAVEITTTLG
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHH
DLLGTFEQSGHSRMPVYSETLDDPRGMVHIRDVLAHITKLARVKKGRTTRKTPVATQLDL
HHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AQVDLARTIGELNLIRQVLFVPPSMLASDLMGRMQTTRTQMALVIDEYGGTDGLVSLEDI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEHHHH
VEMVVGDIEDEHDDDEPMITQAGDGVFIVDGKAEIDEVAKMIGEDFAAGEHGEYVDTIGG
HHHHHHCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
MIFNTLGRVPARGEVVQAIPGFEFHVLDADPRRVKRVRIVQSQKGERRRRATARTEQA
HHHHHHCCCCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDTPETAARPDAGSAPKASDTSEEGSSPSTVTGSAASELSPAGPSLFDRVLGLFRQRNG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
TSLREEIAGALAETASDAESFSPGERAMLNNILRLREVRVEDVMVPRADIEAVEITTTLG
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHH
DLLGTFEQSGHSRMPVYSETLDDPRGMVHIRDVLAHITKLARVKKGRTTRKTPVATQLDL
HHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AQVDLARTIGELNLIRQVLFVPPSMLASDLMGRMQTTRTQMALVIDEYGGTDGLVSLEDI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEHHHH
VEMVVGDIEDEHDDDEPMITQAGDGVFIVDGKAEIDEVAKMIGEDFAAGEHGEYVDTIGG
HHHHHHCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
MIFNTLGRVPARGEVVQAIPGFEFHVLDADPRRVKRVRIVQSQKGERRRRATARTEQA
HHHHHHCCCCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA