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The map label for this gene is mdtA [H]

Identifier: 13474601

GI number: 13474601

Start: 4428804

End: 4429874

Strand: Reverse

Name: mdtA [H]

Synonym: mll5519

Alternate gene names: 13474601

Gene position: 4429874-4428804 (Counterclockwise)

Preceding gene: 13474602

Following gene: 13474600

Centisome position: 62.96

GC content: 66.95

Gene sequence:

>1071_bases
ATGAACCGGTCCATCGTGTTTGGCCTGTTCGCGCTTGGCGTGCTCGCCGCATGCTCGAAATCGGATGAAAAGCCGCCGGA
GATCATCCGGCCTGTTCTGTCGGTCGTGGTCGAGCCGCGCACGACGCAAACCTTCGGCTTTGCCGGCTCGGTCGAGCCGC
AGATCAGCGCCGACCTTGCGTTCCGCCTGCTTGGCCGGGTCGTCTCGCGCGACGTCAAGGTCGGCGATATCGTCAGCAAG
GGCACGACGATCGCCGCGCTCGACCCGACCGCGCTGGAGCTGGCGGTGCAAGCGGCCAGGGCCGAGCTCTCCAATGCAGA
GGCCCAGTTCGCCAATGCTGCCGCCAGCGAGGAGCGCCAGCGCCAGTTGCTCGCCTCGGCCAACGCCACGCAGGCCGTCT
TCGATGCCGCGCAGCAGGCACGCAAAGCCGCGGAAGCCAATGTCGAGCGCGCCAAGGCTTCGCTGGCCAAATCGCAGGAG
CAGCTTGGCTATGCCAGGCTGTTCTCGGATTTCGACGGCGTCGTCACGGCTGTCGGCGCCGAGGTCGGTCAGACCGTCTC
GGCCGGCCAGACGGTCGTCACGGTGGCGCGCTCGGACCTGCGCGAAGCCGTGGTCGATATTCCCGATCAGTTGACCGGCG
ATCTGACCACAGGCACGCCTTTCCAGGTCATCCTGCAATCACTGCCGACGATCGAGACCCAGGCCAAGCTGCGCGAGATC
GCGCCGCAGGCCGAGGGCTCGACCCGCACCCGGCGCGTCAAGCTGACGCTCACGGATCCGCCACAGGCCTTCCGGCTCGG
CTCGACGGTGACGGCGATCCGCGTGACCAAGGTGGCACCGACGATCGAACTGCCCATGTCGGCGCTGCTGGAAAAGAACG
GTGCCGACAAGGTGTGGATCGTCGATCCGCAGACATCGAGCGTGAGCACGCGCGACATCAAGGTCGCGTCGAAGAATGGC
GGCACCTTCACGGTGGCCGAAGGGCTTGACGCCGGCATGCGCGTCGTCACCGCGGGCGTCAACAGCCTGAGCGAAGGCCA
GAAGGTCAGAGTGCCGGAGGGGGGCGTCTGA

Upstream 100 bases:

>100_bases
TCGTCATCGCCAGCGGGCTGAACGAAGGCCAAAGCGTCGTGACCGCAGGCGGGCAGTTGCTCAGTCCCGGCCAGACGGTC
GAGATATCGGGGGCGGCCCA

Downstream 100 bases:

>100_bases
TGAAGGGCTTCAATCTCTCCGACTGGGCGCTCAGCCACCGCTCCATGGTCTGGTATTTCATGCTGGTCTTCGTCGTGGCC
GGCATCTTCTCCTACCTCAA

Product: RND efflux membrane fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNRSIVFGLFALGVLAACSKSDEKPPEIIRPVLSVVVEPRTTQTFGFAGSVEPQISADLAFRLLGRVVSRDVKVGDIVSK
GTTIAALDPTALELAVQAARAELSNAEAQFANAAASEERQRQLLASANATQAVFDAAQQARKAAEANVERAKASLAKSQE
QLGYARLFSDFDGVVTAVGAEVGQTVSAGQTVVTVARSDLREAVVDIPDQLTGDLTTGTPFQVILQSLPTIETQAKLREI
APQAEGSTRTRRVKLTLTDPPQAFRLGSTVTAIRVTKVAPTIELPMSALLEKNGADKVWIVDPQTSSVSTRDIKVASKNG
GTFTVAEGLDAGMRVVTAGVNSLSEGQKVRVPEGGV

Sequences:

>Translated_356_residues
MNRSIVFGLFALGVLAACSKSDEKPPEIIRPVLSVVVEPRTTQTFGFAGSVEPQISADLAFRLLGRVVSRDVKVGDIVSK
GTTIAALDPTALELAVQAARAELSNAEAQFANAAASEERQRQLLASANATQAVFDAAQQARKAAEANVERAKASLAKSQE
QLGYARLFSDFDGVVTAVGAEVGQTVSAGQTVVTVARSDLREAVVDIPDQLTGDLTTGTPFQVILQSLPTIETQAKLREI
APQAEGSTRTRRVKLTLTDPPQAFRLGSTVTAIRVTKVAPTIELPMSALLEKNGADKVWIVDPQTSSVSTRDIKVASKNG
GTFTVAEGLDAGMRVVTAGVNSLSEGQKVRVPEGGV
>Mature_356_residues
MNRSIVFGLFALGVLAACSKSDEKPPEIIRPVLSVVVEPRTTQTFGFAGSVEPQISADLAFRLLGRVVSRDVKVGDIVSK
GTTIAALDPTALELAVQAARAELSNAEAQFANAAASEERQRQLLASANATQAVFDAAQQARKAAEANVERAKASLAKSQE
QLGYARLFSDFDGVVTAVGAEVGQTVSAGQTVVTVARSDLREAVVDIPDQLTGDLTTGTPFQVILQSLPTIETQAKLREI
APQAEGSTRTRRVKLTLTDPPQAFRLGSTVTAIRVTKVAPTIELPMSALLEKNGADKVWIVDPQTSSVSTRDIKVASKNG
GTFTVAEGLDAGMRVVTAGVNSLSEGQKVRVPEGGV

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=371, Percent_Identity=25.3369272237197, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082036, Length=304, Percent_Identity=25.6578947368421, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081796, Length=324, Percent_Identity=22.8395061728395, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37421; Mature: 37421

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSIVFGLFALGVLAACSKSDEKPPEIIRPVLSVVVEPRTTQTFGFAGSVEPQISADLA
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHH
FRLLGRVVSRDVKVGDIVSKGTTIAALDPTALELAVQAARAELSNAEAQFANAAASEERQ
HHHHHHHHHCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLLASANATQAVFDAAQQARKAAEANVERAKASLAKSQEQLGYARLFSDFDGVVTAVGA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVGQTVSAGQTVVTVARSDLREAVVDIPDQLTGDLTTGTPFQVILQSLPTIETQAKLREI
HHCCHHHCCCCEEHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
APQAEGSTRTRRVKLTLTDPPQAFRLGSTVTAIRVTKVAPTIELPMSALLEKNGADKVWI
CCCCCCCCCEEEEEEEECCCCHHHHCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCEEEE
VDPQTSSVSTRDIKVASKNGGTFTVAEGLDAGMRVVTAGVNSLSEGQKVRVPEGGV
ECCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MNRSIVFGLFALGVLAACSKSDEKPPEIIRPVLSVVVEPRTTQTFGFAGSVEPQISADLA
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHH
FRLLGRVVSRDVKVGDIVSKGTTIAALDPTALELAVQAARAELSNAEAQFANAAASEERQ
HHHHHHHHHCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLLASANATQAVFDAAQQARKAAEANVERAKASLAKSQEQLGYARLFSDFDGVVTAVGA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVGQTVSAGQTVVTVARSDLREAVVDIPDQLTGDLTTGTPFQVILQSLPTIETQAKLREI
HHCCHHHCCCCEEHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
APQAEGSTRTRRVKLTLTDPPQAFRLGSTVTAIRVTKVAPTIELPMSALLEKNGADKVWI
CCCCCCCCCEEEEEEEECCCCHHHHCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCEEEE
VDPQTSSVSTRDIKVASKNGGTFTVAEGLDAGMRVVTAGVNSLSEGQKVRVPEGGV
ECCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA