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The map label for this gene is dppB [H]

Identifier: 13474596

GI number: 13474596

Start: 4422119

End: 4423180

Strand: Direct

Name: dppB [H]

Synonym: mlr5514

Alternate gene names: 13474596

Gene position: 4422119-4423180 (Clockwise)

Preceding gene: 13474595

Following gene: 13474597

Centisome position: 62.85

GC content: 62.15

Gene sequence:

>1062_bases
ATGAGCGCGATTGAAAACGAGAGCGGGCGCGGTAGCGCCCGCGCCGTCGCCATTGCGTCGGCGATTGGCCGTTTCCTGGT
CATCGCGGTGACGACCTATCTTGGTCTTCTCGCGGTGACCTTCTTTATCGGCCGTGTCATCCCGATCGATCCGGTGCTGG
CGGTGCTCGGCGACCGGGCGCCTCTCAATGTCGTGGAGCGCACGCGCCGCGAGATGGGCCTCGACCTGCCGCTGATCGAA
CAGTTCTACATCTACGTGAAAAATGCCCTGAACGGTGATTTCGGCACATCTGTGCTGACCACCAACCCGGTCATGACCGA
CATTCGCCGCGCGTTGCCGGCGACGACGGAACTGGCGACGCTGGGGACACTGATCGGCGCGCTGTTCGGCGTGCCGCTCG
GCGTGCTGGCCGCGGTCAGGCGCGGCAGCATCATCGACCAGATCGTGCGCGTCATTGGCCTGATCGGCTATTCCGTGCCG
ATCTTCTGGCTCGGCCTGCTTGGCCTCGTCCTGTTCTACGCCAAGCTGCAATGGGTGGCTTTTCCGGCCCGGCTCGATGT
CGTCTACGAATACACCTTCACGCCGGTCACCGGTTTCTACCTTCTCGATTCGGCGATGCAGGGTCAGTGGGATGTCTTCT
GGGATGCCTTCCGCCACATCATCCTGCCGGCCTCGCTGCTCGGCTATTTCTCGCTCGCCTATATCAGCCGCATGACACGC
TCGTTCATGCTCAACGAACTTGCGCAGGAATACATCGTTGCCGCCCGCGCCAAGGGCCTGTCGGAGACCCGCATCATCTG
GGGCCACGCGCTGCGCAATGCCGCGGTGCCGATGGTGACGGTGATCGCGCTCTCCTATGCCGGCCTTCTCGAAGGCTCGG
TGCTGACCGAAACCGTCTTCTCCTGGCCGGGCATCGGCCTCTACATCACCAACTCGTTGCAGAACGCCGACATGAATGCC
GTGCTCGGCGGCACCATCGTCATTGGTTCAGTGTTCATCGGCATCAACCTTCTGTCCGATCTTCTCTACCGCGTGCTCGA
TCCAAGGACGAAGACAGGATGA

Upstream 100 bases:

>100_bases
CGGGCTGCGCAAGAACCTCAAGGGCTTCGCGCTCGGTCCGAGCTTCGACAGCAACTTCGTCGGCCCGGTCTCGAAAGAAT
AAAGTCGACGGACGCGCCAC

Downstream 100 bases:

>100_bases
GCACAGACACCATCCAGAGCCGTCGCGATTGGCTGCTCAGCGAGCGCCCGGCTTCGCGCATGCAGGCAAGGCTTGGCCGC
GCCTATGTCGCGTGGCGGCG

Product: ABC transporter, permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSAIENESGRGSARAVAIASAIGRFLVIAVTTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPLNVVERTRREMGLDLPLIE
QFYIYVKNALNGDFGTSVLTTNPVMTDIRRALPATTELATLGTLIGALFGVPLGVLAAVRRGSIIDQIVRVIGLIGYSVP
IFWLGLLGLVLFYAKLQWVAFPARLDVVYEYTFTPVTGFYLLDSAMQGQWDVFWDAFRHIILPASLLGYFSLAYISRMTR
SFMLNELAQEYIVAARAKGLSETRIIWGHALRNAAVPMVTVIALSYAGLLEGSVLTETVFSWPGIGLYITNSLQNADMNA
VLGGTIVIGSVFIGINLLSDLLYRVLDPRTKTG

Sequences:

>Translated_353_residues
MSAIENESGRGSARAVAIASAIGRFLVIAVTTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPLNVVERTRREMGLDLPLIE
QFYIYVKNALNGDFGTSVLTTNPVMTDIRRALPATTELATLGTLIGALFGVPLGVLAAVRRGSIIDQIVRVIGLIGYSVP
IFWLGLLGLVLFYAKLQWVAFPARLDVVYEYTFTPVTGFYLLDSAMQGQWDVFWDAFRHIILPASLLGYFSLAYISRMTR
SFMLNELAQEYIVAARAKGLSETRIIWGHALRNAAVPMVTVIALSYAGLLEGSVLTETVFSWPGIGLYITNSLQNADMNA
VLGGTIVIGSVFIGINLLSDLLYRVLDPRTKTG
>Mature_352_residues
SAIENESGRGSARAVAIASAIGRFLVIAVTTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPLNVVERTRREMGLDLPLIEQ
FYIYVKNALNGDFGTSVLTTNPVMTDIRRALPATTELATLGTLIGALFGVPLGVLAAVRRGSIIDQIVRVIGLIGYSVPI
FWLGLLGLVLFYAKLQWVAFPARLDVVYEYTFTPVTGFYLLDSAMQGQWDVFWDAFRHIILPASLLGYFSLAYISRMTRS
FMLNELAQEYIVAARAKGLSETRIIWGHALRNAAVPMVTVIALSYAGLLEGSVLTETVFSWPGIGLYITNSLQNADMNAV
LGGTIVIGSVFIGINLLSDLLYRVLDPRTKTG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=334, Percent_Identity=41.9161676646707, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1787761, Length=319, Percent_Identity=44.8275862068966, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787053, Length=330, Percent_Identity=32.4242424242424, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789888, Length=331, Percent_Identity=33.5347432024169, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=31.7518248175182, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787497, Length=325, Percent_Identity=28.9230769230769, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1788504, Length=292, Percent_Identity=30.8219178082192, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38457; Mature: 38326

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIENESGRGSARAVAIASAIGRFLVIAVTTYLGLLAVTFFIGRVIPIDPVLAVLGDRA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PLNVVERTRREMGLDLPLIEQFYIYVKNALNGDFGTSVLTTNPVMTDIRRALPATTELAT
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHCCCHHHHHH
LGTLIGALFGVPLGVLAAVRRGSIIDQIVRVIGLIGYSVPIFWLGLLGLVLFYAKLQWVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FPARLDVVYEYTFTPVTGFYLLDSAMQGQWDVFWDAFRHIILPASLLGYFSLAYISRMTR
EHHHEEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFMLNELAQEYIVAARAKGLSETRIIWGHALRNAAVPMVTVIALSYAGLLEGSVLTETVF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SWPGIGLYITNSLQNADMNAVLGGTIVIGSVFIGINLLSDLLYRVLDPRTKTG
HCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAIENESGRGSARAVAIASAIGRFLVIAVTTYLGLLAVTFFIGRVIPIDPVLAVLGDRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PLNVVERTRREMGLDLPLIEQFYIYVKNALNGDFGTSVLTTNPVMTDIRRALPATTELAT
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHCCCHHHHHH
LGTLIGALFGVPLGVLAAVRRGSIIDQIVRVIGLIGYSVPIFWLGLLGLVLFYAKLQWVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FPARLDVVYEYTFTPVTGFYLLDSAMQGQWDVFWDAFRHIILPASLLGYFSLAYISRMTR
EHHHEEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFMLNELAQEYIVAARAKGLSETRIIWGHALRNAAVPMVTVIALSYAGLLEGSVLTETVF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SWPGIGLYITNSLQNADMNAVLGGTIVIGSVFIGINLLSDLLYRVLDPRTKTG
HCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]