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The map label for this gene is yccK [H]

Identifier: 13474214

GI number: 13474214

Start: 4001878

End: 4002876

Strand: Direct

Name: yccK [H]

Synonym: mlr5051

Alternate gene names: 13474214

Gene position: 4001878-4002876 (Clockwise)

Preceding gene: 13474208

Following gene: 13474223

Centisome position: 56.88

GC content: 63.26

Gene sequence:

>999_bases
GTGATGCAAACCCGCAAGCTAGGAACTGAATTGAACGTTTATCCCGTCGGCCTCGGCTGCATGGGTATGAGCTTCGCCTA
TGGCGGCCAGCCGGAGGCAGAGGCGATCTCCACGCTGCACCGCGCTGTCGAGATCGGCGTCAACTTCTTCGACACCGCGG
AAGTCTACGGCCCTTACGAGAACGAGATCCTGCTCGGCAAGGCGCTGAAATCGATGCGCGACAAGGTCACCATCGCCACC
AAATTCGGCTTCAAGATTCTAGAGGAAGGCACCGGCCTCGACCGCATGGCCGGCGTCGACAGCCGCCCCGAGCACGTCAA
GGCCGTTGCCGAGGCCTCGCTGAAGCGGTTGGGCACCGATGTCATCGATCTCTACTACCAGCACCGTGTCGACCCCAACG
TGCCGATCGAGGATACGGTCGGTGCCATGGCCGAACTGGTGCGCGAGGGCAAGGTCCGCGCGCTCGGCCTCTCGGAGGCA
AGTGCCGCGACCATCCGCCGTGCGCATGCCGTGCATCCGATCGCTGCCGTGCAGAGCGAATATTCGCTGTGGACCCGTGA
CCCGGAAGAGGAGGTGTTTGCCGTCTGCCGCGAACTCGGCATCGGCTTCGTTCCCTACAGCCCACTCGGCCGTGGCCTTT
TGACCGGCACCATCGCCAAGCCCGAAACGCTAGACGATGGCGACTGGCGCCGGACCTTGCCGCGCTTCCAGGCCGAGGCC
ATGGAAGCCAATGCCAAGGTTATCGCCACGCTGGAAACAATGGCTGCCGAGAAGGGCGTGACCTCGGCGCAGCTGGCGCT
GGCCTGGGTGCTGCATCAGGGTGATTTTATCGTGCCGATCCCCGGTGCACGAAAAATCCGCCATCTGGAGCAGAACACGG
CAGCGGCCGCGATTGAACTGAGTGCTGCCGAGGTGGCGGCGATCGGCGATGCGCTGTCACCGGATAAGGTGATGGGCAAA
CGCTATACGGAGGAGTTGCTGGCGCTGGTGAATGGCTAG

Upstream 100 bases:

>100_bases
GGTTCATTGATCTATTTCTTGGAACGGGCCGTACGAAGAAGAGCCGATTATCGAACAGACTGCAAGGCGCTATTTCTGCT
GCATCACAACAAGGAGACGC

Downstream 100 bases:

>100_bases
GGCCTTCACCCTCCCCCTCGTGGGGAGGGTCGGCTCGCTGTCGCAGCGAAGCGGAGGCAGCGAGACGGGGTGGGGGAGCG
CCTACGAGTACCCCCACCCC

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MMQTRKLGTELNVYPVGLGCMGMSFAYGGQPEAEAISTLHRAVEIGVNFFDTAEVYGPYENEILLGKALKSMRDKVTIAT
KFGFKILEEGTGLDRMAGVDSRPEHVKAVAEASLKRLGTDVIDLYYQHRVDPNVPIEDTVGAMAELVREGKVRALGLSEA
SAATIRRAHAVHPIAAVQSEYSLWTRDPEEEVFAVCRELGIGFVPYSPLGRGLLTGTIAKPETLDDGDWRRTLPRFQAEA
MEANAKVIATLETMAAEKGVTSAQLALAWVLHQGDFIVPIPGARKIRHLEQNTAAAAIELSAAEVAAIGDALSPDKVMGK
RYTEELLALVNG

Sequences:

>Translated_332_residues
MMQTRKLGTELNVYPVGLGCMGMSFAYGGQPEAEAISTLHRAVEIGVNFFDTAEVYGPYENEILLGKALKSMRDKVTIAT
KFGFKILEEGTGLDRMAGVDSRPEHVKAVAEASLKRLGTDVIDLYYQHRVDPNVPIEDTVGAMAELVREGKVRALGLSEA
SAATIRRAHAVHPIAAVQSEYSLWTRDPEEEVFAVCRELGIGFVPYSPLGRGLLTGTIAKPETLDDGDWRRTLPRFQAEA
MEANAKVIATLETMAAEKGVTSAQLALAWVLHQGDFIVPIPGARKIRHLEQNTAAAAIELSAAEVAAIGDALSPDKVMGK
RYTEELLALVNG
>Mature_332_residues
MMQTRKLGTELNVYPVGLGCMGMSFAYGGQPEAEAISTLHRAVEIGVNFFDTAEVYGPYENEILLGKALKSMRDKVTIAT
KFGFKILEEGTGLDRMAGVDSRPEHVKAVAEASLKRLGTDVIDLYYQHRVDPNVPIEDTVGAMAELVREGKVRALGLSEA
SAATIRRAHAVHPIAAVQSEYSLWTRDPEEEVFAVCRELGIGFVPYSPLGRGLLTGTIAKPETLDDGDWRRTLPRFQAEA
MEANAKVIATLETMAAEKGVTSAQLALAWVLHQGDFIVPIPGARKIRHLEQNTAAAAIELSAAEVAAIGDALSPDKVMGK
RYTEELLALVNG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=344, Percent_Identity=29.0697674418605, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI4504825, Length=341, Percent_Identity=29.0322580645161, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI27436964, Length=317, Percent_Identity=30.2839116719243, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436966, Length=317, Percent_Identity=30.2839116719243, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436962, Length=317, Percent_Identity=30.2839116719243, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI27436971, Length=289, Percent_Identity=32.1799307958478, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI223718702, Length=310, Percent_Identity=30, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI41327764, Length=285, Percent_Identity=30.5263157894737, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=228, Percent_Identity=29.3859649122807, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=341, Percent_Identity=31.6715542521994, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788070, Length=311, Percent_Identity=34.4051446945338, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=29.483282674772, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787674, Length=321, Percent_Identity=29.595015576324, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=28.0528052805281, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=29.9418604651163, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI48994888, Length=133, Percent_Identity=30.8270676691729, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564128, Length=305, Percent_Identity=23.6065573770492, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=311, Percent_Identity=30.8681672025724, Blast_Score=125, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=290, Percent_Identity=30.6896551724138, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325384, Length=353, Percent_Identity=27.7620396600567, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325169, Length=347, Percent_Identity=26.8011527377522, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=30.241935483871, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=281, Percent_Identity=28.4697508896797, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646155, Length=163, Percent_Identity=36.8098159509202, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640980, Length=323, Percent_Identity=25.6965944272446, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45549126, Length=323, Percent_Identity=25.6965944272446, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553081, Length=292, Percent_Identity=27.3972602739726, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24657054, Length=333, Percent_Identity=22.8228228228228, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35933; Mature: 35933

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTRKLGTELNVYPVGLGCMGMSFAYGGQPEAEAISTLHRAVEIGVNFFDTAEVYGPYE
CCCCHHCCCCCEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEECHHHCCCCC
NEILLGKALKSMRDKVTIATKFGFKILEEGTGLDRMAGVDSRPEHVKAVAEASLKRLGTD
CCCHHHHHHHHHHHHEEEEHHHCHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCHH
VIDLYYQHRVDPNVPIEDTVGAMAELVREGKVRALGLSEASAATIRRAHAVHPIAAVQSE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHH
YSLWTRDPEEEVFAVCRELGIGFVPYSPLGRGLLTGTIAKPETLDDGDWRRTLPRFQAEA
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHH
MEANAKVIATLETMAAEKGVTSAQLALAWVLHQGDFIVPIPGARKIRHLEQNTAAAAIEL
HHCCCCEEEHHHHHHHHCCCCHHHHHHHHHEECCCEEEECCCHHHHHHHHHHHHHHEEEE
SAAEVAAIGDALSPDKVMGKRYTEELLALVNG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMQTRKLGTELNVYPVGLGCMGMSFAYGGQPEAEAISTLHRAVEIGVNFFDTAEVYGPYE
CCCCHHCCCCCEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEECHHHCCCCC
NEILLGKALKSMRDKVTIATKFGFKILEEGTGLDRMAGVDSRPEHVKAVAEASLKRLGTD
CCCHHHHHHHHHHHHEEEEHHHCHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCHH
VIDLYYQHRVDPNVPIEDTVGAMAELVREGKVRALGLSEASAATIRRAHAVHPIAAVQSE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHH
YSLWTRDPEEEVFAVCRELGIGFVPYSPLGRGLLTGTIAKPETLDDGDWRRTLPRFQAEA
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHH
MEANAKVIATLETMAAEKGVTSAQLALAWVLHQGDFIVPIPGARKIRHLEQNTAAAAIEL
HHCCCCEEEHHHHHHHHCCCCHHHHHHHHHEECCCEEEECCCHHHHHHHHHHHHHHEEEE
SAAEVAAIGDALSPDKVMGKRYTEELLALVNG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]