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The map label for this gene is lip2 [H]

Identifier: 13474208

GI number: 13474208

Start: 3995859

End: 3996797

Strand: Direct

Name: lip2 [H]

Synonym: mlr5045

Alternate gene names: 13474208

Gene position: 3995859-3996797 (Clockwise)

Preceding gene: 13474207

Following gene: 13474214

Centisome position: 56.79

GC content: 66.13

Gene sequence:

>939_bases
ATGACCGACTACACAAAACTCATCGATGCCGAGACCTGGGCCTTCATCGAGCGGACCAATTCCTATTATCCGCCCGACAC
GATCGACTACACGATCACCCAGCAGCGCGAGATCTACGACCGCATGTGCCGGGAGTTCTTTGCCGGCTATCCCCAGGGCG
TGACGGTCGAAACCTCGGCCATTGCCACGCCCACGCACGATATCCCGATCCGTATCTACCGAAGCGCCCCGCAACCGGCG
GCGACGGTGCTCTGCATCCATGGCGGCGGCTTCATGCTTGGCGGGCTGGACAGCCATGACGACGTCTGCGCCGAGCTTTG
CGCCCGCACCGGCTACGAAGTTGTCTCGGTCGACTATCGGCTGGCGCCGGAGCATTTGCATCCTGCCGCCTTCGACGACG
CGATGACCGCCTTCGCATGGGTTGCATCCACCCGCGATCGCCCCATCCTGCTCTGCGGCGACAGCGCCGGCGGCAATCTC
TGCGCCGCCGTCAGCCACGCCACGCGCGGCCACGTGAAACGGCCGGTCGGTCAGGTGCTGATCTATCCCGGTCTCGGCGG
CGACCGCTCGAAGGACTCCTATGTCACGCATGCCGAAGCACCGATGCTGACCATGCGCGATCTTGAATTCTACAAGCACA
TTCGCACCGGCGGGCAGGATCGCAGCGGCGATGCCACACTGGCGCCGCTGGCCGACACCGACTTCGCCAACCTGCCGCCG
ACCGTGCTGGTCACCGCGCAGTGCGACCCGCTGTCTTCAGACGGCGAGACCTATCGCGACCGCATCATCGCGGCGGGCGG
GAGAGCCACCTGGTTCGAGGAACCGGGCCTGGTGCATGGCTATCTCAGGGCCCGGCACACGGTCGGCCGCGCCCGCGAAA
GTTTCACACGGATCGTCGGCGCGGCGGCCGCGCTTGGGCAGGGCGCCTGGCTCTGGTAA

Upstream 100 bases:

>100_bases
GAGGGTCGGACCGAAGGTCCGGGGTGGGGTGAAGCGCCGCCACCCCCACCCGCCGCTCCGCGGCGACCTCCCCCCATCAA
GGGGAAGGTAAAGGAGTTCC

Downstream 100 bases:

>100_bases
GCGGTTTCCGTCTCACGACGGGCCACCGCACCGTCGTTTCACGCCACCGAGCGTCCCGCCGCTCGGCCGGCGCTGCGGCC
GGAGAAGATGCAGCCGCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTDYTKLIDAETWAFIERTNSYYPPDTIDYTITQQREIYDRMCREFFAGYPQGVTVETSAIATPTHDIPIRIYRSAPQPA
ATVLCIHGGGFMLGGLDSHDDVCAELCARTGYEVVSVDYRLAPEHLHPAAFDDAMTAFAWVASTRDRPILLCGDSAGGNL
CAAVSHATRGHVKRPVGQVLIYPGLGGDRSKDSYVTHAEAPMLTMRDLEFYKHIRTGGQDRSGDATLAPLADTDFANLPP
TVLVTAQCDPLSSDGETYRDRIIAAGGRATWFEEPGLVHGYLRARHTVGRARESFTRIVGAAAALGQGAWLW

Sequences:

>Translated_312_residues
MTDYTKLIDAETWAFIERTNSYYPPDTIDYTITQQREIYDRMCREFFAGYPQGVTVETSAIATPTHDIPIRIYRSAPQPA
ATVLCIHGGGFMLGGLDSHDDVCAELCARTGYEVVSVDYRLAPEHLHPAAFDDAMTAFAWVASTRDRPILLCGDSAGGNL
CAAVSHATRGHVKRPVGQVLIYPGLGGDRSKDSYVTHAEAPMLTMRDLEFYKHIRTGGQDRSGDATLAPLADTDFANLPP
TVLVTAQCDPLSSDGETYRDRIIAAGGRATWFEEPGLVHGYLRARHTVGRARESFTRIVGAAAALGQGAWLW
>Mature_311_residues
TDYTKLIDAETWAFIERTNSYYPPDTIDYTITQQREIYDRMCREFFAGYPQGVTVETSAIATPTHDIPIRIYRSAPQPAA
TVLCIHGGGFMLGGLDSHDDVCAELCARTGYEVVSVDYRLAPEHLHPAAFDDAMTAFAWVASTRDRPILLCGDSAGGNLC
AAVSHATRGHVKRPVGQVLIYPGLGGDRSKDSYVTHAEAPMLTMRDLEFYKHIRTGGQDRSGDATLAPLADTDFANLPPT
VLVTAQCDPLSSDGETYRDRIIAAGGRATWFEEPGLVHGYLRARHTVGRARESFTRIVGAAAALGQGAWLW

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI206597554, Length=172, Percent_Identity=34.8837209302326, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157041239, Length=149, Percent_Identity=29.5302013422819, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI61966717, Length=310, Percent_Identity=22.5806451612903, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21328446, Length=118, Percent_Identity=35.5932203389831, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786682, Length=303, Percent_Identity=27.7227722772277, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567059, Length=294, Percent_Identity=24.1496598639456, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540028, Length=132, Percent_Identity=34.0909090909091, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71996133, Length=129, Percent_Identity=34.1085271317829, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72001146, Length=112, Percent_Identity=34.8214285714286, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 34115; Mature: 33983

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYTKLIDAETWAFIERTNSYYPPDTIDYTITQQREIYDRMCREFFAGYPQGVTVETSA
CCCHHHHHCCHHHHEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEECCE
IATPTHDIPIRIYRSAPQPAATVLCIHGGGFMLGGLDSHDDVCAELCARTGYEVVSVDYR
ECCCCCCCCEEEEECCCCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHCCCEEEEEEEE
LAPEHLHPAAFDDAMTAFAWVASTRDRPILLCGDSAGGNLCAAVSHATRGHVKRPVGQVL
ECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEHHHHHHCHHCCCCCCEE
IYPGLGGDRSKDSYVTHAEAPMLTMRDLEFYKHIRTGGQDRSGDATLAPLADTDFANLPP
EECCCCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
TVLVTAQCDPLSSDGETYRDRIIAAGGRATWFEEPGLVHGYLRARHTVGRARESFTRIVG
EEEEEEECCCCCCCCHHHHHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAALGQGAWLW
HHHHHCCCCCCC
>Mature Secondary Structure 
TDYTKLIDAETWAFIERTNSYYPPDTIDYTITQQREIYDRMCREFFAGYPQGVTVETSA
CCHHHHHCCHHHHEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEECCE
IATPTHDIPIRIYRSAPQPAATVLCIHGGGFMLGGLDSHDDVCAELCARTGYEVVSVDYR
ECCCCCCCCEEEEECCCCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHCCCEEEEEEEE
LAPEHLHPAAFDDAMTAFAWVASTRDRPILLCGDSAGGNLCAAVSHATRGHVKRPVGQVL
ECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEHHHHHHCHHCCCCCCEE
IYPGLGGDRSKDSYVTHAEAPMLTMRDLEFYKHIRTGGQDRSGDATLAPLADTDFANLPP
EECCCCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
TVLVTAQCDPLSSDGETYRDRIIAAGGRATWFEEPGLVHGYLRARHTVGRARESFTRIVG
EEEEEEECCCCCCCCHHHHHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAALGQGAWLW
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]