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The map label for this gene is rocF [H]

Identifier: 13474185

GI number: 13474185

Start: 3973326

End: 3974162

Strand: Direct

Name: rocF [H]

Synonym: mlr5015

Alternate gene names: 13474185

Gene position: 3973326-3974162 (Clockwise)

Preceding gene: 13474184

Following gene: 13474186

Centisome position: 56.47

GC content: 65.23

Gene sequence:

>837_bases
GTGAAGATCACCATCATCCTCGCCTCCTATGACAGCGGCCACTATCATGGCGGCATGGGCCAGGGCCCGGATGCGCTGAT
CGCAGGCGGTCTGGTCGACGCCCTGACCATTGCCGGCCACGAGGTCGCGGTCGCGGATATCGGCAGGGTTGGTGACGACC
AGGAGCGCGAGATCGCCACCGGTTTTGCCGTCTGCAACGCCGTCTCGGGCGAGGTTCGCATTGCCATCGACAGGGGACGG
TTCCCCATCGTGCTCGCCGGAAACTGCCTGACATCAGCCGGCGCGGTCGCCGGCGAGGGTGCCGACGCGATCATCTGGGC
CGACCAGCATGGCGACCTCAACACGCCCGAAACCTCGGTTTATGGCTTTCTCGACGGCATGGCGCTGGCGACCGTGCTTG
GCCTGTGCTGGCGTCCGATGGCAGGGGCCATTCCAGGCTTCAAGCCGATCGACCCGTCACGCTGCGTGCTCGTCAATGCC
CGCGATCTCGATCCGGCCGAGGAAGAACTCCTCAAGACCTTGCCGGTCATCCGCACCGAATGTCCAGGCATTGGACCGGC
AACCGCAAAGCTGAAGGCCGTAGGCGCCAAAAGCGTGCACATGCATCTCGATCTCGACGTGCACGACCCCAAGGAACTGC
AGGCCAATCGATACGTCACGTCAGGCGGGCCAAGCCCCGGACAATTGCGCGACGCGGCCTGCGCCATGGCGCTTGCGGTG
CCAGTCGTCGGCATCACCGTTTCCGCTTACGATCCGGCCTTCGACGCGCGGGGTGACGTCCCGCCGTTGGTCGGCGAGCT
GCTCAACGATCTCATCGCCACGATAGAGGGCCGCTGA

Upstream 100 bases:

>100_bases
AGAAGCTCGAAGGCGCCATCTCCGGTCGCGCGCTCTATGACGGCCGCATCGATCCGGCCGAGGCGCTGGCGATCCTGCAG
GGTCGGCCGGAGGCGAAATC

Downstream 100 bases:

>100_bases
TGCTGAAAGCCCGTGTCATCCCGTGCCTCGACGTCAAGGACGGCCGCGTCGTCAAGGGCGTCAACTTCGTCGACCTCATC
GACGCCGGCGACCCGGTCGA

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKITIILASYDSGHYHGGMGQGPDALIAGGLVDALTIAGHEVAVADIGRVGDDQEREIATGFAVCNAVSGEVRIAIDRGR
FPIVLAGNCLTSAGAVAGEGADAIIWADQHGDLNTPETSVYGFLDGMALATVLGLCWRPMAGAIPGFKPIDPSRCVLVNA
RDLDPAEEELLKTLPVIRTECPGIGPATAKLKAVGAKSVHMHLDLDVHDPKELQANRYVTSGGPSPGQLRDAACAMALAV
PVVGITVSAYDPAFDARGDVPPLVGELLNDLIATIEGR

Sequences:

>Translated_278_residues
MKITIILASYDSGHYHGGMGQGPDALIAGGLVDALTIAGHEVAVADIGRVGDDQEREIATGFAVCNAVSGEVRIAIDRGR
FPIVLAGNCLTSAGAVAGEGADAIIWADQHGDLNTPETSVYGFLDGMALATVLGLCWRPMAGAIPGFKPIDPSRCVLVNA
RDLDPAEEELLKTLPVIRTECPGIGPATAKLKAVGAKSVHMHLDLDVHDPKELQANRYVTSGGPSPGQLRDAACAMALAV
PVVGITVSAYDPAFDARGDVPPLVGELLNDLIATIEGR
>Mature_278_residues
MKITIILASYDSGHYHGGMGQGPDALIAGGLVDALTIAGHEVAVADIGRVGDDQEREIATGFAVCNAVSGEVRIAIDRGR
FPIVLAGNCLTSAGAVAGEGADAIIWADQHGDLNTPETSVYGFLDGMALATVLGLCWRPMAGAIPGFKPIDPSRCVLVNA
RDLDPAEEELLKTLPVIRTECPGIGPATAKLKAVGAKSVHMHLDLDVHDPKELQANRYVTSGGPSPGQLRDAACAMALAV
PVVGITVSAYDPAFDARGDVPPLVGELLNDLIATIEGR

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=237, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 28760; Mature: 28760

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIILASYDSGHYHGGMGQGPDALIAGGLVDALTIAGHEVAVADIGRVGDDQEREIAT
CEEEEEEEECCCCCCCCCCCCCCHHHHHCHHHHHHHHCCCEEEEEHHCCCCCCHHHHHHH
GFAVCNAVSGEVRIAIDRGRFPIVLAGNCLTSAGAVAGEGADAIIWADQHGDLNTPETSV
HHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHH
YGFLDGMALATVLGLCWRPMAGAIPGFKPIDPSRCVLVNARDLDPAEEELLKTLPVIRTE
HHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHC
CPGIGPATAKLKAVGAKSVHMHLDLDVHDPKELQANRYVTSGGPSPGQLRDAACAMALAV
CCCCCCCHHEEEECCCCEEEEEEEECCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHHHH
PVVGITVSAYDPAFDARGDVPPLVGELLNDLIATIEGR
HHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKITIILASYDSGHYHGGMGQGPDALIAGGLVDALTIAGHEVAVADIGRVGDDQEREIAT
CEEEEEEEECCCCCCCCCCCCCCHHHHHCHHHHHHHHCCCEEEEEHHCCCCCCHHHHHHH
GFAVCNAVSGEVRIAIDRGRFPIVLAGNCLTSAGAVAGEGADAIIWADQHGDLNTPETSV
HHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHH
YGFLDGMALATVLGLCWRPMAGAIPGFKPIDPSRCVLVNARDLDPAEEELLKTLPVIRTE
HHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHC
CPGIGPATAKLKAVGAKSVHMHLDLDVHDPKELQANRYVTSGGPSPGQLRDAACAMALAV
CCCCCCCHHEEEECCCCEEEEEEEECCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHHHH
PVVGITVSAYDPAFDARGDVPPLVGELLNDLIATIEGR
HHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]