Click here to switch to the map view.

The map label for this gene is aroG [H]

Identifier: 13474165

GI number: 13474165

Start: 3955676

End: 3956767

Strand: Reverse

Name: aroG [H]

Synonym: mll4988

Alternate gene names: 13474165

Gene position: 3956767-3955676 (Counterclockwise)

Preceding gene: 13474166

Following gene: 13474163

Centisome position: 56.24

GC content: 66.48

Gene sequence:

>1092_bases
GTGTTGACCACCACAGACGACCTCCGGGTCAAGGAAATCCGAGAACTGAGCACGCCGGACCAGGTGATGCGGGAAATCCC
GCGCACGCTGACGGCGACGCGCACCGTGAGCGCCTCACGCAATGCGATCCACGCTATTCTGAACGGCACCGACGACCGGC
TGCTTGTCGTCGTCGGTCCCTGTTCGATCCACGATCCGGTCGCGGCCGTTGACTATGCCAGCCGTCTGGCGGCGCTGCGC
GAGACCCTGTCCGACCGGCTTGAGATCGTGATGCGGGTGTATTTCGAGAAGCCGCGCACCACGGTCGGCTGGAAGGGCCT
GATCAACGATCCCGACCTTGACGGCAGCTTCAACATCGACAAGGGGCTCAGGATGGCACGCAACGTGCTTTCCGCCGTCA
ACAATCTCGGCCTGCCGGCGGCCACCGAATTCCTCGACATGACCACGCCGCAATACATTGCCGACCTCGTCGCCTGGGGT
GCCATCGGCGCGCGCACCACCGAAAGCCAAATCCACCGTGAGCTGGCCTCGGGCCTGTCCTGCCCGGTCGGTTTCAAGAA
CGGCACCGACGGCAATCTCAGGATCGCCGGCGAGGCGGTGAAATCGGCCGCCCAGCCGCATCATTTCATGGCGGTGACCA
AGGGCGGACGCAGCGGCATCGCCACCACCACCGGCAATGAGGACTGCCATGTCATCCTGCGCGGCGGCGTTCAGCCCAAC
TACGACGCGGCGAGCGTCGAGGCGGCCTCGGTCGAACTCGCCCGCATCGGTGTCGCGCCGCGGCTGATGATCGATGTCAG
CCACGCCAACTCCGCCAAGAAGCCTGAGAACCAGCCGAAGGTGGCGGCCGATGTGGCCGGCCAGGTGGCGGCGGGCGACG
AGCGCATCATCGGCCTGATGATCGAGAGCAATCTCGTCGCCGGCCGGCAGGACGTGGTGCCCGGCAAGCCGCTCGTCTAT
GGCCAGAGCATCACCGATGGCTGCATCGACTGGGCGACCACCGAGACCGTGCTGCATGGCCTTGCCGGTGCCGTCGAGTG
GCGCCGGTCGGCACGCCGCGCCATGCTGGAAAGCCGGCAGGGTGCTGCCTGA

Upstream 100 bases:

>100_bases
GCGCTCGATCTGAAGATTGCAGCAACAAGATCCGAACAGCCGCCAGACCTGGCGGCTTTTTTGTTTCAGCCGGCAGGTCT
CCTAACAGGAGCAGAAAGCC

Downstream 100 bases:

>100_bases
CACGGCTGACGATATCGGAAGGGCGGCGCTAGATTACGCCGCCCTCAGCCCTTCCCAGGCGGTGAACACCGAGACGGCAA
AAAGCAGCAGCCCGGCCGCC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLTTTDDLRVKEIRELSTPDQVMREIPRTLTATRTVSASRNAIHAILNGTDDRLLVVVGPCSIHDPVAAVDYASRLAALR
ETLSDRLEIVMRVYFEKPRTTVGWKGLINDPDLDGSFNIDKGLRMARNVLSAVNNLGLPAATEFLDMTTPQYIADLVAWG
AIGARTTESQIHRELASGLSCPVGFKNGTDGNLRIAGEAVKSAAQPHHFMAVTKGGRSGIATTTGNEDCHVILRGGVQPN
YDAASVEAASVELARIGVAPRLMIDVSHANSAKKPENQPKVAADVAGQVAAGDERIIGLMIESNLVAGRQDVVPGKPLVY
GQSITDGCIDWATTETVLHGLAGAVEWRRSARRAMLESRQGAA

Sequences:

>Translated_363_residues
MLTTTDDLRVKEIRELSTPDQVMREIPRTLTATRTVSASRNAIHAILNGTDDRLLVVVGPCSIHDPVAAVDYASRLAALR
ETLSDRLEIVMRVYFEKPRTTVGWKGLINDPDLDGSFNIDKGLRMARNVLSAVNNLGLPAATEFLDMTTPQYIADLVAWG
AIGARTTESQIHRELASGLSCPVGFKNGTDGNLRIAGEAVKSAAQPHHFMAVTKGGRSGIATTTGNEDCHVILRGGVQPN
YDAASVEAASVELARIGVAPRLMIDVSHANSAKKPENQPKVAADVAGQVAAGDERIIGLMIESNLVAGRQDVVPGKPLVY
GQSITDGCIDWATTETVLHGLAGAVEWRRSARRAMLESRQGAA
>Mature_363_residues
MLTTTDDLRVKEIRELSTPDQVMREIPRTLTATRTVSASRNAIHAILNGTDDRLLVVVGPCSIHDPVAAVDYASRLAALR
ETLSDRLEIVMRVYFEKPRTTVGWKGLINDPDLDGSFNIDKGLRMARNVLSAVNNLGLPAATEFLDMTTPQYIADLVAWG
AIGARTTESQIHRELASGLSCPVGFKNGTDGNLRIAGEAVKSAAQPHHFMAVTKGGRSGIATTTGNEDCHVILRGGVQPN
YDAASVEAASVELARIGVAPRLMIDVSHANSAKKPENQPKVAADVAGQVAAGDERIIGLMIESNLVAGRQDVVPGKPLVY
GQSITDGCIDWATTETVLHGLAGAVEWRRSARRAMLESRQGAA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=349, Percent_Identity=61.0315186246418, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1787996, Length=347, Percent_Identity=52.7377521613833, Blast_Score=373, Evalue=1e-105,
Organism=Escherichia coli, GI1788953, Length=350, Percent_Identity=50.5714285714286, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319726, Length=351, Percent_Identity=54.4159544159544, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320240, Length=354, Percent_Identity=50, Blast_Score=350, Evalue=3e-97,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38803; Mature: 38803

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTTDDLRVKEIRELSTPDQVMREIPRTLTATRTVSASRNAIHAILNGTDDRLLVVVGP
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCEEEEEECC
CSIHDPVAAVDYASRLAALRETLSDRLEIVMRVYFEKPRTTVGWKGLINDPDLDGSFNID
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
KGLRMARNVLSAVNNLGLPAATEFLDMTTPQYIADLVAWGAIGARTTESQIHRELASGLS
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
CPVGFKNGTDGNLRIAGEAVKSAAQPHHFMAVTKGGRSGIATTTGNEDCHVILRGGVQPN
CCCCCCCCCCCCEEEECHHHHHCCCCCEEEEEECCCCCCCEECCCCCCEEEEEECCCCCC
YDAASVEAASVELARIGVAPRLMIDVSHANSAKKPENQPKVAADVAGQVAAGDERIIGLM
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHCCCCCEEEEEE
IESNLVAGRQDVVPGKPLVYGQSITDGCIDWATTETVLHGLAGAVEWRRSARRAMLESRQ
EECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAA
CCC
>Mature Secondary Structure
MLTTTDDLRVKEIRELSTPDQVMREIPRTLTATRTVSASRNAIHAILNGTDDRLLVVVGP
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCEEEEEECC
CSIHDPVAAVDYASRLAALRETLSDRLEIVMRVYFEKPRTTVGWKGLINDPDLDGSFNID
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
KGLRMARNVLSAVNNLGLPAATEFLDMTTPQYIADLVAWGAIGARTTESQIHRELASGLS
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
CPVGFKNGTDGNLRIAGEAVKSAAQPHHFMAVTKGGRSGIATTTGNEDCHVILRGGVQPN
CCCCCCCCCCCCEEEECHHHHHCCCCCEEEEEECCCCCCCEECCCCCCEEEEEECCCCCC
YDAASVEAASVELARIGVAPRLMIDVSHANSAKKPENQPKVAADVAGQVAAGDERIIGLM
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHCCCCCEEEEEE
IESNLVAGRQDVVPGKPLVYGQSITDGCIDWATTETVLHGLAGAVEWRRSARRAMLESRQ
EECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]