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The map label for this gene is yfcG [H]

Identifier: 13474138

GI number: 13474138

Start: 3927034

End: 3927738

Strand: Direct

Name: yfcG [H]

Synonym: mlr4954

Alternate gene names: 13474138

Gene position: 3927034-3927738 (Clockwise)

Preceding gene: 13474137

Following gene: 13474143

Centisome position: 55.81

GC content: 62.55

Gene sequence:

>705_bases
ATGGCCGACCTGTCCGCCTTTCCGATCACAACCCGCTGGCCGGCCAAATATCCCGACCAGATCCAGCTCTATTCGGCAAC
GACGCCCAACGGCGTGAAGATATCGATCGCGCTGGAAGAGGTCGGCCTGCCCTATGAGCCGCATCTGGTCAACATCAGCA
AGGACGAAAGCTGGACGCCGGAATTCCTGTCGCTCAATCCCAATGGCAAGATTCCGGCGATCATCGATCCCAACGGCCCG
GACGGCAAGCCGATCGGCCTTTTCGAATCCGGCGCCATCCTGCTCTATCTCGCCGACAAGACCGGCTTGCTCGTCCCGGC
GGACGCAGCGCGGCGCTACGAGACGATCCAGTGGGTCTTCTTCCAGATGGCTTCCGTCGGGCCGATGTTCGGCCAGGTCG
GGTTCTTCCACAAATTCGCCGGCCGCGAGATCGCCGACAAGCGCCCGCTGGAGCGCTACCGCGACGAATCGCGGCGGCTG
ATCGGCGTGCTCGACGGCCGATTGAAGGGTCGCAAATGGATCATGGGCAACGACTACACCATCGCCGACATCTCGCTGCT
CGGCTGGGTGCGCAATTTGATCGGCTTCTATGAAGCGCGCGAGCTCGTCGGTTTCGATGATTTCGCCAATGTAGCGGCAT
GGCTGGAGCGCGGCCTGGCGCGACCGGCGGTGCAAAAGGGCCTGACCATTCCGGCCAAGGGCTAA

Upstream 100 bases:

>100_bases
AACCGTCGCTGCCATATTGATCCGGCCCGGCCCTGCGCCTAATTCTTGGCCACCCGCCAACACCGCGCCCTTGCCGCAAA
TCCCCGCTCAGGAGTTCTCG

Downstream 100 bases:

>100_bases
ACCGCCTGTCGCCACAGGGCGACGAGCTTGGCCAAAGATATCTGAGCGGACGAAGCAGCCTGCTACTTCGCCTTGGCCTT
CGAGCCGCCCCTGCCGATCA

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MADLSAFPITTRWPAKYPDQIQLYSATTPNGVKISIALEEVGLPYEPHLVNISKDESWTPEFLSLNPNGKIPAIIDPNGP
DGKPIGLFESGAILLYLADKTGLLVPADAARRYETIQWVFFQMASVGPMFGQVGFFHKFAGREIADKRPLERYRDESRRL
IGVLDGRLKGRKWIMGNDYTIADISLLGWVRNLIGFYEARELVGFDDFANVAAWLERGLARPAVQKGLTIPAKG

Sequences:

>Translated_234_residues
MADLSAFPITTRWPAKYPDQIQLYSATTPNGVKISIALEEVGLPYEPHLVNISKDESWTPEFLSLNPNGKIPAIIDPNGP
DGKPIGLFESGAILLYLADKTGLLVPADAARRYETIQWVFFQMASVGPMFGQVGFFHKFAGREIADKRPLERYRDESRRL
IGVLDGRLKGRKWIMGNDYTIADISLLGWVRNLIGFYEARELVGFDDFANVAAWLERGLARPAVQKGLTIPAKG
>Mature_233_residues
ADLSAFPITTRWPAKYPDQIQLYSATTPNGVKISIALEEVGLPYEPHLVNISKDESWTPEFLSLNPNGKIPAIIDPNGPD
GKPIGLFESGAILLYLADKTGLLVPADAARRYETIQWVFFQMASVGPMFGQVGFFHKFAGREIADKRPLERYRDESRRLI
GVLDGRLKGRKWIMGNDYTIADISLLGWVRNLIGFYEARELVGFDDFANVAAWLERGLARPAVQKGLTIPAKG

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4503481, Length=170, Percent_Identity=31.1764705882353, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=43.0622009569378, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI87082195, Length=224, Percent_Identity=37.0535714285714, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI87081789, Length=207, Percent_Identity=27.536231884058, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=243, Percent_Identity=32.5102880658436, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28571670, Length=182, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17864592, Length=188, Percent_Identity=28.1914893617021, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17864598, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646249, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17933730, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26051; Mature: 25920

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLSAFPITTRWPAKYPDQIQLYSATTPNGVKISIALEEVGLPYEPHLVNISKDESWTP
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEHHHCCCCCCCEEEEECCCCCCCC
EFLSLNPNGKIPAIIDPNGPDGKPIGLFESGAILLYLADKTGLLVPADAARRYETIQWVF
CEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCEEEECHHHHHHHHHHHHH
FQMASVGPMFGQVGFFHKFAGREIADKRPLERYRDESRRLIGVLDGRLKGRKWIMGNDYT
HHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCEEEEEECCCCCCCEEEECCCCE
IADISLLGWVRNLIGFYEARELVGFDDFANVAAWLERGLARPAVQKGLTIPAKG
EHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
ADLSAFPITTRWPAKYPDQIQLYSATTPNGVKISIALEEVGLPYEPHLVNISKDESWTP
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEHHHCCCCCCCEEEEECCCCCCCC
EFLSLNPNGKIPAIIDPNGPDGKPIGLFESGAILLYLADKTGLLVPADAARRYETIQWVF
CEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCEEEECHHHHHHHHHHHHH
FQMASVGPMFGQVGFFHKFAGREIADKRPLERYRDESRRLIGVLDGRLKGRKWIMGNDYT
HHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCEEEEEECCCCCCCEEEECCCCE
IADISLLGWVRNLIGFYEARELVGFDDFANVAAWLERGLARPAVQKGLTIPAKG
EHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]