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The map label for this gene is xdhA [H]

Identifier: 13474083

GI number: 13474083

Start: 3874042

End: 3876366

Strand: Reverse

Name: xdhA [H]

Synonym: mll4880

Alternate gene names: 13474083

Gene position: 3876366-3874042 (Counterclockwise)

Preceding gene: 13474084

Following gene: 13474082

Centisome position: 55.09

GC content: 65.08

Gene sequence:

>2325_bases
ATGGAGGCCTCCTCGCAAACGGCAAGCCTCGATTTCCGCCTGCCTCAGTCCGGCCATGCGATCGGCGCGTCACCCGTCAG
GCTGGACGGTGTGCCAAAGGTGACCGGGGCTGAGAAATTCGGTGGCGATTCCTTCCCGGCCGATGCGCTTGCCGTGCTGG
TTGTCCGTTCGCCGCACTATCACGCCGGCTTCGCCTTCGGCGATCTCGACGGGTGGACAAGGAAGCACCCCGGCATCGTC
GGTATCTTCACGGCGGCCGACATTCCGGGGAAAAATTGTTTTGGCGTCATCGGCCCGTTCGCCGACCAGCCGGCGCTCGC
CGAAGGGTTTGCGCGGCTGCGCGGCGAGGCGGTGGCGCTGGTCGCCGGCGAGCGTGAGGCGATCCTCGATCTGGACCTGT
CGGATTTTCCGATCCGCTGGACCGAACTGCCGCATGTCCTGCAGCCCAGCGAAGCACAGGGCGAGGGTGCTGCCCTGATC
CATCCGCACCGCCCCTCGAACCTGCTGACCTCCGGCTTCGTCGAGCGCGGCGACCCCGAGGCGGCGCTAGCCAATGCGGC
CGTTACCGTGACGGGCGCGATCGACACCTCCTATGTCGAGCACGCCTATATCGAGCCGGAGGCCGGCCATGCCTATATGG
ATGGCGACACGTTGGTCGTCGTCGCCTGCACCCAGGCGCCCTATATGGACCGCGACGATATGGCGAAGGTGCTTGGTCTG
CCCGTCGACAAGGTGCGCATCGTACCGACCGCCACCGGCGGCGGCTTCGGCTCCAAGCTCGACGTTTCGCTGCAGCCGCT
GATCGGCCTTGTGGCGCTGAAGACCGGCCGGCCGGCCGCCTTGGCCTACACCCGCAACGAATCGATGATGTCGACCACCA
AGCGCCATCCGGCCGAAATGAAGGCGACCATCGGCGCCGATGCCGACGGCCATGTCACCGGCATGATCTTTTCAGGCGAT
TTCAACACAGGAGCCTACGCCAGCTGGGGGCCGACCGTCGCCAACCGCGTGCCGGTGCATGCTTCCGGCCCTTATGCGAC
GCCGAACTACCGCGCCGAAGGCCGCGCCATCCACACGCATGGCCCGATCTCCGGCGCCTTCCGTGGCTTCGGCGTACCGC
AGGCGACGATCATGCAGGAGACACTTTATGACGAGCTGGCCGGCAAGCTCGGCATCGACCGCCTCGACTTTCGCCTGAGA
AACTGCCTTCGGAACGGATCCGAAACGGTTACCGGCCAGAGGCTGGAATCCGGCGTCGGCATTGCAGAATGTCTCGAGGC
CTTGCGGCCGCATTGGGCACGGGCGCTGGCTGACGCGGGTGCTTTCAACAGTAACCATGCAGATAAAAAGCGCGGCGTCG
GCGTGGCGTCCTGCTGGTATGGCTGCGGCAACACCTCGCTGCCCAATCCATCGACCATCCGGGTCGGCATCGCGGCTGAC
GGCACCGTCATCCTGCACCAGGGCGCGGTCGACATCGGCCAGGGTTCGAACACCGTCATCTCGCAGATTTGTGCCGACGC
GCTTGGCCTGCCGCTGGAAAGATTCCGGTTGAAGAGCGCCGATACGGCGATCAGTCCCGATGCCGGCAAGACCTCGGCCT
CGCGCCAGACCTTTGTGACCGGCAAAGCCGCCGAAAAAGCTGGCCGTGCCTTGCGCGAAAAGATCCTGCGCTTTGCCAAT
GTCTCCGAAAAGGCATCTCTGCAACTGGACGGCGCGGTGATCGTCATCCGCGAAGGCGAAGCCACGCGCCGCATCGATCT
CGCCTCGCTCGACATGGATGCCGACGGCTTCGTCTTCCGCGCCGAGGAGACCTACGACCCGCCGACGCTGCCGCTCGATG
CCAAGGGCCAGGGCAAGCCCTATGCCGTCTATGGCTATGGCGCGCAGATCGCCGAGCTCGAGGTCGATCTCAAGCTGGGC
ACAGTGAAGCTCCTGAAAATAACTGCCGCGCATGATGTCGGCAAGGCGATCAATCCGTTGCTGGTCGAGGGCCAGATCGA
GGGCGGCATCGCGCAAGGCATCGGCATGGCGCTGATGGAAGAGTACATTCCCGGCCGCACCGAGAATTTGCACGACTATC
TCATCCCAACCATCGGCGACGTGCCGCCGATCGAGACCATCCTGGTCGAGGTTCCCGATCCCGAAGGGCCGTTCGGCGCC
AAGGGCCTGGGTGAGCATGTGCTGATCCCGACCGCGCCGGCGATCCTCAACGCCATCCGCCATGCCACCGGCGTGCTGGT
CACCAAGGTTCCGGCGACGCCGACGCGCATCCGCGCTGGCATCCGTGAAAAAGATGGCATCCGCGAAAAGGAGGCACGCG
CATGA

Upstream 100 bases:

>100_bases
ACTGGACACGACGCCGAGACCAACCGAGACCGAGGTACAGGATGCGCTGGGCGGGATTCTGTGCCGCTGCACCGGCTACC
GGAAGATCATCGCGGCGGTG

Downstream 100 bases:

>100_bases
GCGAGCTTGCCGAGCGTTTCGAGACCCATGATCCCGGCGAGAAGCAGGTGGCGGAGAAGATCCGCTGCGATGCCTGTCCG
GTCATGTGCTACATAGCCGA

Product: aldehyde oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 774

Protein sequence:

>774_residues
MEASSQTASLDFRLPQSGHAIGASPVRLDGVPKVTGAEKFGGDSFPADALAVLVVRSPHYHAGFAFGDLDGWTRKHPGIV
GIFTAADIPGKNCFGVIGPFADQPALAEGFARLRGEAVALVAGEREAILDLDLSDFPIRWTELPHVLQPSEAQGEGAALI
HPHRPSNLLTSGFVERGDPEAALANAAVTVTGAIDTSYVEHAYIEPEAGHAYMDGDTLVVVACTQAPYMDRDDMAKVLGL
PVDKVRIVPTATGGGFGSKLDVSLQPLIGLVALKTGRPAALAYTRNESMMSTTKRHPAEMKATIGADADGHVTGMIFSGD
FNTGAYASWGPTVANRVPVHASGPYATPNYRAEGRAIHTHGPISGAFRGFGVPQATIMQETLYDELAGKLGIDRLDFRLR
NCLRNGSETVTGQRLESGVGIAECLEALRPHWARALADAGAFNSNHADKKRGVGVASCWYGCGNTSLPNPSTIRVGIAAD
GTVILHQGAVDIGQGSNTVISQICADALGLPLERFRLKSADTAISPDAGKTSASRQTFVTGKAAEKAGRALREKILRFAN
VSEKASLQLDGAVIVIREGEATRRIDLASLDMDADGFVFRAEETYDPPTLPLDAKGQGKPYAVYGYGAQIAELEVDLKLG
TVKLLKITAAHDVGKAINPLLVEGQIEGGIAQGIGMALMEEYIPGRTENLHDYLIPTIGDVPPIETILVEVPDPEGPFGA
KGLGEHVLIPTAPAILNAIRHATGVLVTKVPATPTRIRAGIREKDGIREKEARA

Sequences:

>Translated_774_residues
MEASSQTASLDFRLPQSGHAIGASPVRLDGVPKVTGAEKFGGDSFPADALAVLVVRSPHYHAGFAFGDLDGWTRKHPGIV
GIFTAADIPGKNCFGVIGPFADQPALAEGFARLRGEAVALVAGEREAILDLDLSDFPIRWTELPHVLQPSEAQGEGAALI
HPHRPSNLLTSGFVERGDPEAALANAAVTVTGAIDTSYVEHAYIEPEAGHAYMDGDTLVVVACTQAPYMDRDDMAKVLGL
PVDKVRIVPTATGGGFGSKLDVSLQPLIGLVALKTGRPAALAYTRNESMMSTTKRHPAEMKATIGADADGHVTGMIFSGD
FNTGAYASWGPTVANRVPVHASGPYATPNYRAEGRAIHTHGPISGAFRGFGVPQATIMQETLYDELAGKLGIDRLDFRLR
NCLRNGSETVTGQRLESGVGIAECLEALRPHWARALADAGAFNSNHADKKRGVGVASCWYGCGNTSLPNPSTIRVGIAAD
GTVILHQGAVDIGQGSNTVISQICADALGLPLERFRLKSADTAISPDAGKTSASRQTFVTGKAAEKAGRALREKILRFAN
VSEKASLQLDGAVIVIREGEATRRIDLASLDMDADGFVFRAEETYDPPTLPLDAKGQGKPYAVYGYGAQIAELEVDLKLG
TVKLLKITAAHDVGKAINPLLVEGQIEGGIAQGIGMALMEEYIPGRTENLHDYLIPTIGDVPPIETILVEVPDPEGPFGA
KGLGEHVLIPTAPAILNAIRHATGVLVTKVPATPTRIRAGIREKDGIREKEARA
>Mature_774_residues
MEASSQTASLDFRLPQSGHAIGASPVRLDGVPKVTGAEKFGGDSFPADALAVLVVRSPHYHAGFAFGDLDGWTRKHPGIV
GIFTAADIPGKNCFGVIGPFADQPALAEGFARLRGEAVALVAGEREAILDLDLSDFPIRWTELPHVLQPSEAQGEGAALI
HPHRPSNLLTSGFVERGDPEAALANAAVTVTGAIDTSYVEHAYIEPEAGHAYMDGDTLVVVACTQAPYMDRDDMAKVLGL
PVDKVRIVPTATGGGFGSKLDVSLQPLIGLVALKTGRPAALAYTRNESMMSTTKRHPAEMKATIGADADGHVTGMIFSGD
FNTGAYASWGPTVANRVPVHASGPYATPNYRAEGRAIHTHGPISGAFRGFGVPQATIMQETLYDELAGKLGIDRLDFRLR
NCLRNGSETVTGQRLESGVGIAECLEALRPHWARALADAGAFNSNHADKKRGVGVASCWYGCGNTSLPNPSTIRVGIAAD
GTVILHQGAVDIGQGSNTVISQICADALGLPLERFRLKSADTAISPDAGKTSASRQTFVTGKAAEKAGRALREKILRFAN
VSEKASLQLDGAVIVIREGEATRRIDLASLDMDADGFVFRAEETYDPPTLPLDAKGQGKPYAVYGYGAQIAELEVDLKLG
TVKLLKITAAHDVGKAINPLLVEGQIEGGIAQGIGMALMEEYIPGRTENLHDYLIPTIGDVPPIETILVEVPDPEGPFGA
KGLGEHVLIPTAPAILNAIRHATGVLVTKVPATPTRIRAGIREKDGIREKEARA

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=746, Percent_Identity=27.0777479892761, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI71773480, Length=771, Percent_Identity=26.8482490272374, Blast_Score=195, Evalue=2e-49,
Organism=Escherichia coli, GI1789230, Length=770, Percent_Identity=33.3766233766234, Blast_Score=353, Evalue=2e-98,
Organism=Escherichia coli, GI1789246, Length=802, Percent_Identity=28.0548628428928, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786478, Length=596, Percent_Identity=29.5302013422819, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17540638, Length=780, Percent_Identity=26.025641025641, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI32566215, Length=694, Percent_Identity=24.3515850144092, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539860, Length=693, Percent_Identity=23.3766233766234, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI17737937, Length=695, Percent_Identity=28.7769784172662, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24647193, Length=695, Percent_Identity=25.0359712230216, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647195, Length=773, Percent_Identity=24.1914618369987, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24647197, Length=567, Percent_Identity=26.2786596119929, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24647201, Length=691, Percent_Identity=23.8784370477569, Blast_Score=121, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 81656; Mature: 81656

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEASSQTASLDFRLPQSGHAIGASPVRLDGVPKVTGAEKFGGDSFPADALAVLVVRSPHY
CCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCCCCCEEEEEEECCCC
HAGFAFGDLDGWTRKHPGIVGIFTAADIPGKNCFGVIGPFADQPALAEGFARLRGEAVAL
CCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHCCCEEEE
VAGEREAILDLDLSDFPIRWTELPHVLQPSEAQGEGAALIHPHRPSNLLTSGFVERGDPE
EECCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCH
AALANAAVTVTGAIDTSYVEHAYIEPEAGHAYMDGDTLVVVACTQAPYMDRDDMAKVLGL
HHHCCCEEEEEECCCCCHHHHEEECCCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHCC
PVDKVRIVPTATGGGFGSKLDVSLQPLIGLVALKTGRPAALAYTRNESMMSTTKRHPAEM
CCCCEEEEEECCCCCCCCEEEEEHHHHEEEEEECCCCCEEEEEECCCHHHHHHHCCCCHH
KATIGADADGHVTGMIFSGDFNTGAYASWGPTVANRVPVHASGPYATPNYRAEGRAIHTH
HEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCEEEEC
GPISGAFRGFGVPQATIMQETLYDELAGKLGIDRLDFRLRNCLRNGSETVTGQRLESGVG
CCCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCC
IAECLEALRPHWARALADAGAFNSNHADKKRGVGVASCWYGCGNTSLPNPSTIRVGIAAD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECC
GTVILHQGAVDIGQGSNTVISQICADALGLPLERFRLKSADTAISPDAGKTSASRQTFVT
CEEEEECCCEECCCCCHHHHHHHHHHHHCCCHHHHEECCCCCCCCCCCCCCCCCCEEEEE
GKAAEKAGRALREKILRFANVSEKASLQLDGAVIVIREGEATRRIDLASLDMDADGFVFR
CHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCEEEEEEECCCCCCEEEE
AEETYDPPTLPLDAKGQGKPYAVYGYGAQIAELEVDLKLGTVKLLKITAAHDVGKAINPL
ECCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEECEEEEEEEEEHHHHHHHCCCE
LVEGQIEGGIAQGIGMALMEEYIPGRTENLHDYLIPTIGDVPPIETILVEVPDPEGPFGA
EEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
KGLGEHVLIPTAPAILNAIRHATGVLVTKVPATPTRIRAGIREKDGIREKEARA
CCCCCEEEECCHHHHHHHHHHHHCEEEEECCCCHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure
MEASSQTASLDFRLPQSGHAIGASPVRLDGVPKVTGAEKFGGDSFPADALAVLVVRSPHY
CCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCCCCCEEEEEEECCCC
HAGFAFGDLDGWTRKHPGIVGIFTAADIPGKNCFGVIGPFADQPALAEGFARLRGEAVAL
CCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHCCCEEEE
VAGEREAILDLDLSDFPIRWTELPHVLQPSEAQGEGAALIHPHRPSNLLTSGFVERGDPE
EECCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCH
AALANAAVTVTGAIDTSYVEHAYIEPEAGHAYMDGDTLVVVACTQAPYMDRDDMAKVLGL
HHHCCCEEEEEECCCCCHHHHEEECCCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHCC
PVDKVRIVPTATGGGFGSKLDVSLQPLIGLVALKTGRPAALAYTRNESMMSTTKRHPAEM
CCCCEEEEEECCCCCCCCEEEEEHHHHEEEEEECCCCCEEEEEECCCHHHHHHHCCCCHH
KATIGADADGHVTGMIFSGDFNTGAYASWGPTVANRVPVHASGPYATPNYRAEGRAIHTH
HEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCEEEEC
GPISGAFRGFGVPQATIMQETLYDELAGKLGIDRLDFRLRNCLRNGSETVTGQRLESGVG
CCCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCC
IAECLEALRPHWARALADAGAFNSNHADKKRGVGVASCWYGCGNTSLPNPSTIRVGIAAD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECC
GTVILHQGAVDIGQGSNTVISQICADALGLPLERFRLKSADTAISPDAGKTSASRQTFVT
CEEEEECCCEECCCCCHHHHHHHHHHHHCCCHHHHEECCCCCCCCCCCCCCCCCCEEEEE
GKAAEKAGRALREKILRFANVSEKASLQLDGAVIVIREGEATRRIDLASLDMDADGFVFR
CHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCEEEEEEECCCCCCEEEE
AEETYDPPTLPLDAKGQGKPYAVYGYGAQIAELEVDLKLGTVKLLKITAAHDVGKAINPL
ECCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEECEEEEEEEEEHHHHHHHCCCE
LVEGQIEGGIAQGIGMALMEEYIPGRTENLHDYLIPTIGDVPPIETILVEVPDPEGPFGA
EEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
KGLGEHVLIPTAPAILNAIRHATGVLVTKVPATPTRIRAGIREKDGIREKEARA
CCCCCEEEECCHHHHHHHHHHHHCEEEEECCCCHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]