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The map label for this gene is trxB [H]

Identifier: 13473898

GI number: 13473898

Start: 3684247

End: 3685362

Strand: Direct

Name: trxB [H]

Synonym: mlr4645

Alternate gene names: 13473898

Gene position: 3684247-3685362 (Clockwise)

Preceding gene: 13473897

Following gene: 13473899

Centisome position: 52.36

GC content: 66.85

Gene sequence:

>1116_bases
ATGAATCCAGGCGAGAAGGACCTCGCCCGCTGCATCGGCCTGCTGCGGCCGATCGACGCCGATACGCTGTATGATGTCGC
CATTGTCGGCGCCGGGCCTGCGGGGCTGGCGGCGGCGGTCTATGCGGCGTCAGAAGGGCTGTCGACCATCGTGCTCGATT
GCCGGGCCTTCGGCGGCCAGGCCGGCGCCTCCTCGCGCATCGAGAACTATCTCGGCTTCCCCACCGGCATCACCGGCATG
GCGCTGATGGCGCGCGCCTACAACCAGGCGCAGAAATTCGGCGTCGAGATGGTGATCCCCGACGAGGCCAAGCTTTTGAG
CGCGGCGGCCGACAATACAGGCGCCCGTTACCTGCTCGATGTCGGCGATGGCGAGACGGTGCGCACGCGCAGCGTGGTGA
TCGCCAGCGGCGCGCGCTACCGTCGTCTCGAGGTCGCCAATTTGTCGCAGTTCGAGGGCACCTCGGTGCATTATTGGGCC
TCGCCCATCGAAGGCCGGCTTTGCGCCGGGCAGGAGGTGGCGCTGGTCGGCGCCGGCAATTCGGCCGGGCAGGCGGCGGT
CTATCTGGCCAGCCATGCGCGCAAGGTGGCGCTGCTGGCGCGCGGCGGCAGCCTCGATGCCTCGATGTCGCGCTATCTGG
TCGAGCGCATCCAGGCGCAGCCGAACATCGAGGTGCTGACCGAGACCGAAATCGAGGCGCTGGAGGGCGAGGAGGGCAAT
CTAGCCACTGTCCGCTGGCGCAACCGCGTCAGCGGCGAAGTGACGACGCGCCCGATCAGCCACCTCTTCCTGTTCATCGG
CGCCGACCCGAACACCGACTGGCTGGCGCAATGCAATGTGGCGCTGGACGCCAAGGGTTTCATCCGCACCGGATCGGAAC
TCGGACCGGAGCATGGCCTGATGGAGACCAGCCGCAGCGGCGTGTTTGCCATCGGCGACGTCCGTTGCGGTTCGGTCAAG
CGCGTCGCGGCGGCCGTCGGTGAGGGTGCCCAGGTGGTCGCGGCCTTGCATGCCTATCTTGCGCGAGACAGCAGCGCTGC
CGTTACGCCTCAAAGCATGATCCCGAAAAGCGGGGACCGGTTTTCGGAAAAAGACCATGCTTCAACGAAGAGATAG

Upstream 100 bases:

>100_bases
CGATTCCGGCAGCGACCCCTGCGCCAAAACTCTGGTCGAACGCTTCGAGGTCGACCCGCACCATCTGCCGGTCGTGCTGT
GTCCGAACGGCAGGCTGCTG

Downstream 100 bases:

>100_bases
TTCAGGAGAGTGTGATGGCGGACGAATGCAGACATGCGGCTGGGATCAAGGATGTGACGCCGAGCGCGCTGGGCTGCGAG
GAATGCCTGAAGAGCGGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MNPGEKDLARCIGLLRPIDADTLYDVAIVGAGPAGLAAAVYAASEGLSTIVLDCRAFGGQAGASSRIENYLGFPTGITGM
ALMARAYNQAQKFGVEMVIPDEAKLLSAAADNTGARYLLDVGDGETVRTRSVVIASGARYRRLEVANLSQFEGTSVHYWA
SPIEGRLCAGQEVALVGAGNSAGQAAVYLASHARKVALLARGGSLDASMSRYLVERIQAQPNIEVLTETEIEALEGEEGN
LATVRWRNRVSGEVTTRPISHLFLFIGADPNTDWLAQCNVALDAKGFIRTGSELGPEHGLMETSRSGVFAIGDVRCGSVK
RVAAAVGEGAQVVAALHAYLARDSSAAVTPQSMIPKSGDRFSEKDHASTKR

Sequences:

>Translated_371_residues
MNPGEKDLARCIGLLRPIDADTLYDVAIVGAGPAGLAAAVYAASEGLSTIVLDCRAFGGQAGASSRIENYLGFPTGITGM
ALMARAYNQAQKFGVEMVIPDEAKLLSAAADNTGARYLLDVGDGETVRTRSVVIASGARYRRLEVANLSQFEGTSVHYWA
SPIEGRLCAGQEVALVGAGNSAGQAAVYLASHARKVALLARGGSLDASMSRYLVERIQAQPNIEVLTETEIEALEGEEGN
LATVRWRNRVSGEVTTRPISHLFLFIGADPNTDWLAQCNVALDAKGFIRTGSELGPEHGLMETSRSGVFAIGDVRCGSVK
RVAAAVGEGAQVVAALHAYLARDSSAAVTPQSMIPKSGDRFSEKDHASTKR
>Mature_371_residues
MNPGEKDLARCIGLLRPIDADTLYDVAIVGAGPAGLAAAVYAASEGLSTIVLDCRAFGGQAGASSRIENYLGFPTGITGM
ALMARAYNQAQKFGVEMVIPDEAKLLSAAADNTGARYLLDVGDGETVRTRSVVIASGARYRRLEVANLSQFEGTSVHYWA
SPIEGRLCAGQEVALVGAGNSAGQAAVYLASHARKVALLARGGSLDASMSRYLVERIQAQPNIEVLTETEIEALEGEEGN
LATVRWRNRVSGEVTTRPISHLFLFIGADPNTDWLAQCNVALDAKGFIRTGSELGPEHGLMETSRSGVFAIGDVRCGSVK
RVAAAVGEGAQVVAALHAYLARDSSAAVTPQSMIPKSGDRFSEKDHASTKR

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=331, Percent_Identity=30.5135951661631, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=30.2839116719243, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320560, Length=331, Percent_Identity=31.4199395770393, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6321898, Length=336, Percent_Identity=30.6547619047619, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 39055; Mature: 39055

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPGEKDLARCIGLLRPIDADTLYDVAIVGAGPAGLAAAVYAASEGLSTIVLDCRAFGGQ
CCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHCCCC
AGASSRIENYLGFPTGITGMALMARAYNQAQKFGVEMVIPDEAKLLSAAADNTGARYLLD
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCEEEEE
VGDGETVRTRSVVIASGARYRRLEVANLSQFEGTSVHYWASPIEGRLCAGQEVALVGAGN
CCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCEECCCEEEEEECCC
SAGQAAVYLASHARKVALLARGGSLDASMSRYLVERIQAQPNIEVLTETEIEALEGEEGN
CCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCC
LATVRWRNRVSGEVTTRPISHLFLFIGADPNTDWLAQCNVALDAKGFIRTGSELGPEHGL
EEEEEECCCCCCCEECCEEEEEEEEEECCCCCCCEEEECEEECCCCCCCCCCCCCCCCCC
METSRSGVFAIGDVRCGSVKRVAAAVGEGAQVVAALHAYLARDSSAAVTPQSMIPKSGDR
HHCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
FSEKDHASTKR
CCCCCCCCCCC
>Mature Secondary Structure
MNPGEKDLARCIGLLRPIDADTLYDVAIVGAGPAGLAAAVYAASEGLSTIVLDCRAFGGQ
CCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHCCCC
AGASSRIENYLGFPTGITGMALMARAYNQAQKFGVEMVIPDEAKLLSAAADNTGARYLLD
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCEEEEE
VGDGETVRTRSVVIASGARYRRLEVANLSQFEGTSVHYWASPIEGRLCAGQEVALVGAGN
CCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCEECCCEEEEEECCC
SAGQAAVYLASHARKVALLARGGSLDASMSRYLVERIQAQPNIEVLTETEIEALEGEEGN
CCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCC
LATVRWRNRVSGEVTTRPISHLFLFIGADPNTDWLAQCNVALDAKGFIRTGSELGPEHGL
EEEEEECCCCCCCEECCEEEEEEEEEECCCCCCCEEEECEEECCCCCCCCCCCCCCCCCC
METSRSGVFAIGDVRCGSVKRVAAAVGEGAQVVAALHAYLARDSSAAVTPQSMIPKSGDR
HHCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
FSEKDHASTKR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795994 [H]