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The map label for this gene is glk

Identifier: 13473894

GI number: 13473894

Start: 3677994

End: 3679019

Strand: Direct

Name: glk

Synonym: mlr4640

Alternate gene names: 13473894

Gene position: 3677994-3679019 (Clockwise)

Preceding gene: 13473893

Following gene: 13473895

Centisome position: 52.27

GC content: 66.47

Gene sequence:

>1026_bases
ATGCCAAGCGTAAGCGATACCGACACGTCGTTGCGGTTTCCGATCCTGATCGGCGACATTGGCGGCACCAATGCGCGCTT
TTCGATCGTGCTCGACGCCAATTCCGAGCCGACCGAGCCGCAGATCGTCCAGACCGCCAATTTCAACACGATCGACGAGG
CGATCCAGGCGGCGGTGCTCGACCGCTCGTCGGTCCGTCCCAATTCGGCGGTGCTGGCGGTGGCCGGTCCGGTCGACGGC
GACGAGATCGAACTCACCAATTGCCCGTGGGTCGTCAAGCCCAGGCAGATGTTTGCCAATCTCGGCTTGAGCGACATTGT
CGTGCTCAACGATTTCGAGGCGCAGGCGCTGGCCGTCGTGGCGCTTGGCGAAGAGCATATGGAAAAGATCGGCGGCGGCA
CGCCGGAGCCCAATGCAGGCCGCGTCGTGCTCGGCCCCGGAACCGGGCTCGGCGTCGCCGGGCTGGTCTATGCCTTGCGC
CACTGGATACCGGTGCCCGGCGAAGGCGGCCATATGGACATCGGTCCGCGCACGCCGCGCGATTTCGAGGTGTTTCCGCA
TATCGAGAAGCTCGAGGGCCGCATTTCCGGCGAACAGATCCTGTGCGGGCGCGGCCTCGTCAACGTCTACCGGGCTGTCG
CCAAGGCGGACGGCAAGCCGGCGCCTTTCACCACGCCGGCCGAGATCACCGGCGCGGCGCTGGCCAAGACCGATCCGGTG
GCTGAGGAAGCGCTGGAGACTTTCGTCACCTGCCTCGGGCGCACCGCCGGCGATCTTGCCCTGGTGTTCATGAGCCGTGG
CGGCGTCTTCTTGACCGGCGGGATCGCCCAAAAAATCGTGCCGGCGCTGAAGGAGGGCAATTTCCGCGCCGCCTTCGAGG
ACAAGGCGCCGCACAGCGCGCTGATGCGCACCATGCCCGTCTATGTCATCACCCATCCGCTGGCGGCCCTTCTCGGCCTT
GCCGCCTATGCCAGGAACCCGTCGCTGTTCGGCGTCCAGACGGCCGGCCGGCGCTGGCAGGCCTGA

Upstream 100 bases:

>100_bases
GCGCGGAGGGGTTCGAAAACCGTTTCCCTTTTCAAACTCATGCGCTAGTCAACGGAGGAACAGCGAGACGCCGTCAGGGG
CGCCGGGGACGGACGAGAGC

Downstream 100 bases:

>100_bases
ACTCCCAGCGCGAAGCGTGGGGCGCCCGCGACGAAGTTAATCAGCCGCGGGCATAGGCAAGCCGGCCGCATGGCGCTAAG
AGGAGTGCCGAATTGCAGCC

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPSVSDTDTSLRFPILIGDIGGTNARFSIVLDANSEPTEPQIVQTANFNTIDEAIQAAVLDRSSVRPNSAVLAVAGPVDG
DEIELTNCPWVVKPRQMFANLGLSDIVVLNDFEAQALAVVALGEEHMEKIGGGTPEPNAGRVVLGPGTGLGVAGLVYALR
HWIPVPGEGGHMDIGPRTPRDFEVFPHIEKLEGRISGEQILCGRGLVNVYRAVAKADGKPAPFTTPAEITGAALAKTDPV
AEEALETFVTCLGRTAGDLALVFMSRGGVFLTGGIAQKIVPALKEGNFRAAFEDKAPHSALMRTMPVYVITHPLAALLGL
AAYARNPSLFGVQTAGRRWQA

Sequences:

>Translated_341_residues
MPSVSDTDTSLRFPILIGDIGGTNARFSIVLDANSEPTEPQIVQTANFNTIDEAIQAAVLDRSSVRPNSAVLAVAGPVDG
DEIELTNCPWVVKPRQMFANLGLSDIVVLNDFEAQALAVVALGEEHMEKIGGGTPEPNAGRVVLGPGTGLGVAGLVYALR
HWIPVPGEGGHMDIGPRTPRDFEVFPHIEKLEGRISGEQILCGRGLVNVYRAVAKADGKPAPFTTPAEITGAALAKTDPV
AEEALETFVTCLGRTAGDLALVFMSRGGVFLTGGIAQKIVPALKEGNFRAAFEDKAPHSALMRTMPVYVITHPLAALLGL
AAYARNPSLFGVQTAGRRWQA
>Mature_340_residues
PSVSDTDTSLRFPILIGDIGGTNARFSIVLDANSEPTEPQIVQTANFNTIDEAIQAAVLDRSSVRPNSAVLAVAGPVDGD
EIELTNCPWVVKPRQMFANLGLSDIVVLNDFEAQALAVVALGEEHMEKIGGGTPEPNAGRVVLGPGTGLGVAGLVYALRH
WIPVPGEGGHMDIGPRTPRDFEVFPHIEKLEGRISGEQILCGRGLVNVYRAVAKADGKPAPFTTPAEITGAALAKTDPVA
EEALETFVTCLGRTAGDLALVFMSRGGVFLTGGIAQKIVPALKEGNFRAAFEDKAPHSALMRTMPVYVITHPLAALLGLA
AYARNPSLFGVQTAGRRWQA

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=311, Percent_Identity=36.9774919614148, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_RHILO (Q98DM2)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105462.1
- ProteinModelPortal:   Q98DM2
- SMR:   Q98DM2
- GeneID:   1228123
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4640
- NMPDR:   fig|266835.1.peg.3566
- HOGENOM:   HBG644410
- OMA:   VDIGGTH
- ProtClustDB:   PRK00292
- BRENDA:   2.7.1.2
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 35991; Mature: 35859

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVSDTDTSLRFPILIGDIGGTNARFSIVLDANSEPTEPQIVQTANFNTIDEAIQAAVL
CCCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHH
DRSSVRPNSAVLAVAGPVDGDEIELTNCPWVVKPRQMFANLGLSDIVVLNDFEAQALAVV
HCCCCCCCCEEEEEECCCCCCEEEECCCCEEECHHHHHHHCCCCEEEEEECCCCCEEEEE
ALGEEHMEKIGGGTPEPNAGRVVLGPGTGLGVAGLVYALRHWIPVPGEGGHMDIGPRTPR
EECHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCC
DFEVFPHIEKLEGRISGEQILCGRGLVNVYRAVAKADGKPAPFTTPAEITGAALAKTDPV
CCCCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHCCCHH
AEEALETFVTCLGRTAGDLALVFMSRGGVFLTGGIAQKIVPALKEGNFRAAFEDKAPHSA
HHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHCCCEEEEECCCCCHHH
LMRTMPVYVITHPLAALLGLAAYARNPSLFGVQTAGRRWQA
HHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PSVSDTDTSLRFPILIGDIGGTNARFSIVLDANSEPTEPQIVQTANFNTIDEAIQAAVL
CCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHH
DRSSVRPNSAVLAVAGPVDGDEIELTNCPWVVKPRQMFANLGLSDIVVLNDFEAQALAVV
HCCCCCCCCEEEEEECCCCCCEEEECCCCEEECHHHHHHHCCCCEEEEEECCCCCEEEEE
ALGEEHMEKIGGGTPEPNAGRVVLGPGTGLGVAGLVYALRHWIPVPGEGGHMDIGPRTPR
EECHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCC
DFEVFPHIEKLEGRISGEQILCGRGLVNVYRAVAKADGKPAPFTTPAEITGAALAKTDPV
CCCCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHCCCHH
AEEALETFVTCLGRTAGDLALVFMSRGGVFLTGGIAQKIVPALKEGNFRAAFEDKAPHSA
HHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHCCCEEEEECCCCCHHH
LMRTMPVYVITHPLAALLGLAAYARNPSLFGVQTAGRRWQA
HHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968