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The map label for this gene is 13473868

Identifier: 13473868

GI number: 13473868

Start: 3654504

End: 3656993

Strand: Reverse

Name: 13473868

Synonym: mll4606

Alternate gene names: NA

Gene position: 3656993-3654504 (Counterclockwise)

Preceding gene: 13473869

Following gene: 13473866

Centisome position: 51.97

GC content: 64.42

Gene sequence:

>2490_bases
ATGGCCGGCCTCGAACAGTATCATACCAAGCGCGATTTCAAGAAGACATCGGAGCCGGCGGGCAAGGTCGCACGCACCGG
GAAAAACGAAGCCGGGGGCATCTTCGTCATCCACAAGCACGCGGCGACCAGGCTGCACTACGACCTTCGGCTCGAGCATG
ACGGCGTGCTGTGGAGCTGGGCGGTGACGCGGGGGCCCAGCCTCGATCCGCACGAGAAGCGGCTGGCCGTCCATGTCGAG
GACCACCCGATCGACTATGCGCCGTTCGAAGGCACGATCCCGAAGGGCGAGTATGGCGGCGGCTCGGTCATCGTCTGGGA
CGAGGGGACATGGATGCCTGAGACCGACCCGGCCAAGGCGATGAAGAAGGGCCACATCAGTTTCGAGCTCAACGGCCACA
AATTGCATGGGCTGTGGCATCTGGTGCGGCTGAAGCCGCGGGCGGGCGAAAAGCGCGACAACTGGCTCTTGATCAAGTCC
GACGATGCCGCGGCGCGCCCGGGCGAGGACATTTTGAAGGAGAGGCCGGAATCGGTGAAGTCGGGCCTGACGATCGAAGA
GGTCGGCGAGGGCAAGGCGGCCAAGGGCCGAAAGCCCGAGGTCTGGCATTCGAACAAGCCGGCCGCCGGCAAGGCGAAGG
CCGCGGCGCGCAAACTCGACTTCATCGAACCGCAGCTGGCGACGCTGGAGCGGGATGCACCGCCGGGCAAGGACTGGCTG
CATGAAGTCAAATTCGACGGCTATCGCATGCAGGCGCATATCGCCGGCACGGATGTGCGGCTCTTGACCCGCACCGGCCT
CGACTGGACGGAAAAATTCGGCGGCGAGATCATTGCCGAGCTCGCCGGGCTGAAGTGCAGCGACGCCATCATCGACGGCG
AGATTGTCGTGCTGGCCGACAGCGGCGTCTCGTCCTTCGCGCTGCTGCAGCAGGATTTGTCGGCGAAGCGGGCAAACCGC
TTCCTCTATTACGTGTTCGACCTGATGCGTCTCGACGGCAAGGATTTGCGCGCCGAGCCGCTGGTCGAGCGCAAGCAGGC
CTTGCAGGAGCTGCTCGGCAAGCAGGCCGAGAACCCGGCGGTGCGTTTCTCCGACCATTTTTTCGAGCCCGGCAAGATCA
TGCTGGAGCATGCCTGCAGGATGGGGCTGGAAGGCGTCGTGTCCAAACGCGCCGATGCGCCCTATCGCAGCGGGCGCGGC
CCGACCTGGGTGAAGTCGAAATGCACGGCACGGCAAGAATTCGTCATCGGCGGCTATCTGCCGTCCGACAAGACCGGGCG
CGGGCTGCGGTCGCTGCTGGTCGGCTACTACGAGGGCGGCAAACTGCAGTACGCCGGTCGTGTCGGCACCGGTTTCTCCG
TCAAGGGCGCGACGGAGCTGAAGACCAGGCTCGACGCGCTGCAGGCGAAGGCTTCGCCCTTCGACAAGGCCGTGCCGAAA
GGCAAGGGCCTGGTCTGGGTCAAGCCGGAATTGGTCGGCGAAGTGGAGTTTCGCAGCTGGACGTCGGACCGTATAGTGCG
TCATGCCTCGTTCCAGGGGCTGCGCGAGGACAAGCCGGCGGAGGACGTTGTGCAGGAAAAGCCCAAGGCAGCGACAGGCA
AGGCCAAGCCGGCCTCGAGCGGCGCCGGGACGATGACGACCAGCGTAAAACTCTCGCATCCCGACAAGCTGCTCTGGCCC
GACGAAAAGATCTCCAAGCAGGGCCTGCTCGACCATTACGCCGAGGTCTGGCCCCGCATGGAGCAGTTCGTCGTCAACCG
GCCGCTCAGCCTGGTGCGGGCGCCGGACGGCATCGGCGGCCCGCGCTTCTTCCAGAAACATGCCTCGGCCGGCATGAGCG
ACAGAATAGCCCGGATGAAGGACCCAACGGATGGCGAGGAGATCCTGTTCGTGCGGGATTTCGACGGTGTGGCGGCACTC
GTCCAGTATGGCGTGGTCGAGATCCACATCTGGGGCTGCACGATCGACAAGCTTGAACAGCCGGACCAGATCATCTTCGA
TCTCGATCCCGATGAAGGCGTCGACGTCAAAGCGGTGCGCGAGGCGGCGCTCGATATAAGGGGGAAGCTCGACGAGCTGT
CGCTGCCGAACTTCGTCAAGACATCGGGCGGCAAGGGCTATCATGTGCTGGTGCCGCTGAAACCGTCGGCGGATTGGGAG
GCGGTGAAGACCTTCGCGCATGATTTCGCCAAGGCGCTCGAGCAGGGTGCCCCCGACCGCTACACGGCGACGCTGTCGAA
GAAGGCGCGGACCGGGAAAATCTTCGTCGACTATCTGCGCAATGGCCGCGGCTCGACGACGGTCGCGCCCTATTCCTCGC
GCGCCAAGAAAGGGGCCACCGTGTCGATGCCGGTGACCTGGGCCGAGATCGAGGCCGGCCTGGCGCCGAATGCTTTCCCT
ATAGGCGACAAGACGACGCTTGCGAAGTTGGCGGAAGCCGACCCGTGGATGGATTTCTTCAAGCAGGGCAAGGTGTTGAA
GCGGGGGTAG

Upstream 100 bases:

>100_bases
CCGGCTCACCTAAATCATCATCCGCAGCCAGGCCGGCGGCCAAACGCGCCAAGCCGAAAGCGGCCGCGCCGAAGCGCAAA
TCGGCCTGAGGAGACCAAGG

Downstream 100 bases:

>100_bases
TTCTCCGCGCTCAGCTCAAAAACACCTTCTCGAAGGCCTGCTTGCCCGGTGGCGAGAAAATCACCGCGCGGCTGTCCTTT
TCGCGGCGCGCCCATTTTTC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MAGLEQYHTKRDFKKTSEPAGKVARTGKNEAGGIFVIHKHAATRLHYDLRLEHDGVLWSWAVTRGPSLDPHEKRLAVHVE
DHPIDYAPFEGTIPKGEYGGGSVIVWDEGTWMPETDPAKAMKKGHISFELNGHKLHGLWHLVRLKPRAGEKRDNWLLIKS
DDAAARPGEDILKERPESVKSGLTIEEVGEGKAAKGRKPEVWHSNKPAAGKAKAAARKLDFIEPQLATLERDAPPGKDWL
HEVKFDGYRMQAHIAGTDVRLLTRTGLDWTEKFGGEIIAELAGLKCSDAIIDGEIVVLADSGVSSFALLQQDLSAKRANR
FLYYVFDLMRLDGKDLRAEPLVERKQALQELLGKQAENPAVRFSDHFFEPGKIMLEHACRMGLEGVVSKRADAPYRSGRG
PTWVKSKCTARQEFVIGGYLPSDKTGRGLRSLLVGYYEGGKLQYAGRVGTGFSVKGATELKTRLDALQAKASPFDKAVPK
GKGLVWVKPELVGEVEFRSWTSDRIVRHASFQGLREDKPAEDVVQEKPKAATGKAKPASSGAGTMTTSVKLSHPDKLLWP
DEKISKQGLLDHYAEVWPRMEQFVVNRPLSLVRAPDGIGGPRFFQKHASAGMSDRIARMKDPTDGEEILFVRDFDGVAAL
VQYGVVEIHIWGCTIDKLEQPDQIIFDLDPDEGVDVKAVREAALDIRGKLDELSLPNFVKTSGGKGYHVLVPLKPSADWE
AVKTFAHDFAKALEQGAPDRYTATLSKKARTGKIFVDYLRNGRGSTTVAPYSSRAKKGATVSMPVTWAEIEAGLAPNAFP
IGDKTTLAKLAEADPWMDFFKQGKVLKRG

Sequences:

>Translated_829_residues
MAGLEQYHTKRDFKKTSEPAGKVARTGKNEAGGIFVIHKHAATRLHYDLRLEHDGVLWSWAVTRGPSLDPHEKRLAVHVE
DHPIDYAPFEGTIPKGEYGGGSVIVWDEGTWMPETDPAKAMKKGHISFELNGHKLHGLWHLVRLKPRAGEKRDNWLLIKS
DDAAARPGEDILKERPESVKSGLTIEEVGEGKAAKGRKPEVWHSNKPAAGKAKAAARKLDFIEPQLATLERDAPPGKDWL
HEVKFDGYRMQAHIAGTDVRLLTRTGLDWTEKFGGEIIAELAGLKCSDAIIDGEIVVLADSGVSSFALLQQDLSAKRANR
FLYYVFDLMRLDGKDLRAEPLVERKQALQELLGKQAENPAVRFSDHFFEPGKIMLEHACRMGLEGVVSKRADAPYRSGRG
PTWVKSKCTARQEFVIGGYLPSDKTGRGLRSLLVGYYEGGKLQYAGRVGTGFSVKGATELKTRLDALQAKASPFDKAVPK
GKGLVWVKPELVGEVEFRSWTSDRIVRHASFQGLREDKPAEDVVQEKPKAATGKAKPASSGAGTMTTSVKLSHPDKLLWP
DEKISKQGLLDHYAEVWPRMEQFVVNRPLSLVRAPDGIGGPRFFQKHASAGMSDRIARMKDPTDGEEILFVRDFDGVAAL
VQYGVVEIHIWGCTIDKLEQPDQIIFDLDPDEGVDVKAVREAALDIRGKLDELSLPNFVKTSGGKGYHVLVPLKPSADWE
AVKTFAHDFAKALEQGAPDRYTATLSKKARTGKIFVDYLRNGRGSTTVAPYSSRAKKGATVSMPVTWAEIEAGLAPNAFP
IGDKTTLAKLAEADPWMDFFKQGKVLKRG
>Mature_828_residues
AGLEQYHTKRDFKKTSEPAGKVARTGKNEAGGIFVIHKHAATRLHYDLRLEHDGVLWSWAVTRGPSLDPHEKRLAVHVED
HPIDYAPFEGTIPKGEYGGGSVIVWDEGTWMPETDPAKAMKKGHISFELNGHKLHGLWHLVRLKPRAGEKRDNWLLIKSD
DAAARPGEDILKERPESVKSGLTIEEVGEGKAAKGRKPEVWHSNKPAAGKAKAAARKLDFIEPQLATLERDAPPGKDWLH
EVKFDGYRMQAHIAGTDVRLLTRTGLDWTEKFGGEIIAELAGLKCSDAIIDGEIVVLADSGVSSFALLQQDLSAKRANRF
LYYVFDLMRLDGKDLRAEPLVERKQALQELLGKQAENPAVRFSDHFFEPGKIMLEHACRMGLEGVVSKRADAPYRSGRGP
TWVKSKCTARQEFVIGGYLPSDKTGRGLRSLLVGYYEGGKLQYAGRVGTGFSVKGATELKTRLDALQAKASPFDKAVPKG
KGLVWVKPELVGEVEFRSWTSDRIVRHASFQGLREDKPAEDVVQEKPKAATGKAKPASSGAGTMTTSVKLSHPDKLLWPD
EKISKQGLLDHYAEVWPRMEQFVVNRPLSLVRAPDGIGGPRFFQKHASAGMSDRIARMKDPTDGEEILFVRDFDGVAALV
QYGVVEIHIWGCTIDKLEQPDQIIFDLDPDEGVDVKAVREAALDIRGKLDELSLPNFVKTSGGKGYHVLVPLKPSADWEA
VKTFAHDFAKALEQGAPDRYTATLSKKARTGKIFVDYLRNGRGSTTVAPYSSRAKKGATVSMPVTWAEIEAGLAPNAFPI
GDKTTLAKLAEADPWMDFFKQGKVLKRG

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324578, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 91470; Mature: 91339

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00141 ASP_PROTEASE ; PS50160 DNA_LIGASE_A3 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLEQYHTKRDFKKTSEPAGKVARTGKNEAGGIFVIHKHAATRLHYDLRLEHDGVLWSW
CCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEEE
AVTRGPSLDPHEKRLAVHVEDHPIDYAPFEGTIPKGEYGGGSVIVWDEGTWMPETDPAKA
EECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHH
MKKGHISFELNGHKLHGLWHLVRLKPRAGEKRDNWLLIKSDDAAARPGEDILKERPESVK
HHCCCEEEEECCCEEECEEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCHHHH
SGLTIEEVGEGKAAKGRKPEVWHSNKPAAGKAKAAARKLDFIEPQLATLERDAPPGKDWL
HCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCHHHH
HEVKFDGYRMQAHIAGTDVRLLTRTGLDWTEKFGGEIIAELAGLKCSDAIIDGEIVVLAD
HHHCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCEEEEEEC
SGVSSFALLQQDLSAKRANRFLYYVFDLMRLDGKDLRAEPLVERKQALQELLGKQAENPA
CCCHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VRFSDHFFEPGKIMLEHACRMGLEGVVSKRADAPYRSGRGPTWVKSKCTARQEFVIGGYL
EEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEECCC
PSDKTGRGLRSLLVGYYEGGKLQYAGRVGTGFSVKGATELKTRLDALQAKASPFDKAVPK
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHCCC
GKGLVWVKPELVGEVEFRSWTSDRIVRHASFQGLREDKPAEDVVQEKPKAATGKAKPASS
CCCEEEECHHHHCCEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
GAGTMTTSVKLSHPDKLLWPDEKISKQGLLDHYAEVWPRMEQFVVNRPLSLVRAPDGIGG
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCC
PRFFQKHASAGMSDRIARMKDPTDGEEILFVRDFDGVAALVQYGVVEIHIWGCTIDKLEQ
HHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCEEEEEEEECCHHHCCC
PDQIIFDLDPDEGVDVKAVREAALDIRGKLDELSLPNFVKTSGGKGYHVLVPLKPSADWE
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEEEEEECCCCCCHH
AVKTFAHDFAKALEQGAPDRYTATLSKKARTGKIFVDYLRNGRGSTTVAPYSSRAKKGAT
HHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCEEEEHHHCCCCCCEECCCHHHCCCCCE
VSMPVTWAEIEAGLAPNAFPIGDKTTLAKLAEADPWMDFFKQGKVLKRG
EEECEEHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCEECCC
>Mature Secondary Structure 
AGLEQYHTKRDFKKTSEPAGKVARTGKNEAGGIFVIHKHAATRLHYDLRLEHDGVLWSW
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEEE
AVTRGPSLDPHEKRLAVHVEDHPIDYAPFEGTIPKGEYGGGSVIVWDEGTWMPETDPAKA
EECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHH
MKKGHISFELNGHKLHGLWHLVRLKPRAGEKRDNWLLIKSDDAAARPGEDILKERPESVK
HHCCCEEEEECCCEEECEEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCHHHH
SGLTIEEVGEGKAAKGRKPEVWHSNKPAAGKAKAAARKLDFIEPQLATLERDAPPGKDWL
HCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCHHHH
HEVKFDGYRMQAHIAGTDVRLLTRTGLDWTEKFGGEIIAELAGLKCSDAIIDGEIVVLAD
HHHCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCEEEEEEC
SGVSSFALLQQDLSAKRANRFLYYVFDLMRLDGKDLRAEPLVERKQALQELLGKQAENPA
CCCHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VRFSDHFFEPGKIMLEHACRMGLEGVVSKRADAPYRSGRGPTWVKSKCTARQEFVIGGYL
EEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEECCC
PSDKTGRGLRSLLVGYYEGGKLQYAGRVGTGFSVKGATELKTRLDALQAKASPFDKAVPK
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHCCC
GKGLVWVKPELVGEVEFRSWTSDRIVRHASFQGLREDKPAEDVVQEKPKAATGKAKPASS
CCCEEEECHHHHCCEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
GAGTMTTSVKLSHPDKLLWPDEKISKQGLLDHYAEVWPRMEQFVVNRPLSLVRAPDGIGG
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCC
PRFFQKHASAGMSDRIARMKDPTDGEEILFVRDFDGVAALVQYGVVEIHIWGCTIDKLEQ
HHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCEEEEEEEECCHHHCCC
PDQIIFDLDPDEGVDVKAVREAALDIRGKLDELSLPNFVKTSGGKGYHVLVPLKPSADWE
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEEEEEECCCCCCHH
AVKTFAHDFAKALEQGAPDRYTATLSKKARTGKIFVDYLRNGRGSTTVAPYSSRAKKGAT
HHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCEEEEHHHCCCCCCEECCCHHHCCCCCE
VSMPVTWAEIEAGLAPNAFPIGDKTTLAKLAEADPWMDFFKQGKVLKRG
EEECEEHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]