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The map label for this gene is 13473850

Identifier: 13473850

GI number: 13473850

Start: 3639384

End: 3640010

Strand: Reverse

Name: 13473850

Synonym: mll4583

Alternate gene names: NA

Gene position: 3640010-3639384 (Counterclockwise)

Preceding gene: 13473851

Following gene: 13473848

Centisome position: 51.73

GC content: 65.23

Gene sequence:

>627_bases
ATGGGTCGAGCGCATACCGTGAGCCGTGGTGAGGATCATCCGCCGATCGCTCGTTCGGAGCTGCCTGATGATACGGCCGC
TCTCGCCCGTTACCTCATCGGCAAGCTGGTGGTGCGCGACTTGCCCGAAGGCATGGTCAGCGGCCGCATCGTCGAGACCG
AGGCCTATGTCGTCGGCGATGCCGCCGGGCATGGTTTCAGGGGGATGACCCCGCGCAACCGTTCGCTGTTCCTCGAGCGC
GGCCACGCCTATGTCTATCTCGCCTATGGCGTCTCCATGATGCTGAATGTCTCAAGCGAGGTACCGGGGATCGGCACCGG
CGTGCTGATCCGGGCGCTCGAGCCGCTCGACGGTATTGAAATCATGCGGCGCAATCGCGGCGTCGAGCGCCTGCGCGACC
TGGCGCGCGGGCCGGGAAGGCTGGCGGCGGCGCTGCGGATCGACCGGTCGCTCGACGGGCTCGACCTCTGCCGGAAAGGC
CCTCTATGGCTGGCGAAGGATAACCAAAAACCCGGCGAGATCGGGCAGAGCACAAGGATCGGCATCACCAAAGATGCCGC
CCGGCTGCTGCGGTTCTATGTCAGGGGCAGCCTGTTCGTCAGCGGTCCGAGATCGCTTCAGGAATAA

Upstream 100 bases:

>100_bases
CCTCCTATACGGTCAGCATCATGGAGTTCCTCGACGGCAAGGTGGCCCGCGAGACCCAGTATTTCAGCGAGGCGTTCGAG
CCGGGACCATCGCGCGCGCA

Downstream 100 bases:

>100_bases
GAGACCAGCCGGCTTTCGCAGCACGACCCCCTCAGACTGCGATTTGCAGCGTTCCGTAGCGCTTTACCTCGGCTTCGATC
TCCCTGACCAAAGTCTCGAG

Product: 3-methyl-adenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MGRAHTVSRGEDHPPIARSELPDDTAALARYLIGKLVVRDLPEGMVSGRIVETEAYVVGDAAGHGFRGMTPRNRSLFLER
GHAYVYLAYGVSMMLNVSSEVPGIGTGVLIRALEPLDGIEIMRRNRGVERLRDLARGPGRLAAALRIDRSLDGLDLCRKG
PLWLAKDNQKPGEIGQSTRIGITKDAARLLRFYVRGSLFVSGPRSLQE

Sequences:

>Translated_208_residues
MGRAHTVSRGEDHPPIARSELPDDTAALARYLIGKLVVRDLPEGMVSGRIVETEAYVVGDAAGHGFRGMTPRNRSLFLER
GHAYVYLAYGVSMMLNVSSEVPGIGTGVLIRALEPLDGIEIMRRNRGVERLRDLARGPGRLAAALRIDRSLDGLDLCRKG
PLWLAKDNQKPGEIGQSTRIGITKDAARLLRFYVRGSLFVSGPRSLQE
>Mature_207_residues
GRAHTVSRGEDHPPIARSELPDDTAALARYLIGKLVVRDLPEGMVSGRIVETEAYVVGDAAGHGFRGMTPRNRSLFLERG
HAYVYLAYGVSMMLNVSSEVPGIGTGVLIRALEPLDGIEIMRRNRGVERLRDLARGPGRLAAALRIDRSLDGLDLCRKGP
LWLAKDNQKPGEIGQSTRIGITKDAARLLRFYVRGSLFVSGPRSLQE

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=191, Percent_Identity=41.8848167539267, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI62632771, Length=191, Percent_Identity=41.8848167539267, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI62632765, Length=191, Percent_Identity=41.8848167539267, Blast_Score=124, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_RHILO (Q98DR6)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105418.1
- ProteinModelPortal:   Q98DR6
- GeneID:   1228079
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4583
- NMPDR:   fig|266835.1.peg.3522
- HOGENOM:   HBG664239
- OMA:   CANIVCG
- ProtClustDB:   CLSK864077
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 22772; Mature: 22640

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAHTVSRGEDHPPIARSELPDDTAALARYLIGKLVVRDLPEGMVSGRIVETEAYVVGD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCEEEEEC
AAGHGFRGMTPRNRSLFLERGHAYVYLAYGVSMMLNVSSEVPGIGTGVLIRALEPLDGIE
CCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHEEECCCCCCCCCHHHHHHHHCCCCHHH
IMRRNRGVERLRDLARGPGRLAAALRIDRSLDGLDLCRKGPLWLAKDNQKPGEIGQSTRI
HHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCC
GITKDAARLLRFYVRGSLFVSGPRSLQE
CCCHHHHHHHHHHHHCCEEECCCHHCCC
>Mature Secondary Structure 
GRAHTVSRGEDHPPIARSELPDDTAALARYLIGKLVVRDLPEGMVSGRIVETEAYVVGD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCEEEEEC
AAGHGFRGMTPRNRSLFLERGHAYVYLAYGVSMMLNVSSEVPGIGTGVLIRALEPLDGIE
CCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHEEECCCCCCCCCHHHHHHHHCCCCHHH
IMRRNRGVERLRDLARGPGRLAAALRIDRSLDGLDLCRKGPLWLAKDNQKPGEIGQSTRI
HHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCC
GITKDAARLLRFYVRGSLFVSGPRSLQE
CCCHHHHHHHHHHHHCCEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968