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The map label for this gene is uxaC

Identifier: 13473453

GI number: 13473453

Start: 3241842

End: 3243251

Strand: Reverse

Name: uxaC

Synonym: mll4056

Alternate gene names: 13473453

Gene position: 3243251-3241842 (Counterclockwise)

Preceding gene: 13473455

Following gene: 13473452

Centisome position: 46.09

GC content: 65.32

Gene sequence:

>1410_bases
ATGGTCGCGCTGACCGATCCGGACCTGCTGTTTCCACCCGAAGCGCATTCGCGCTCGCTTGCCCGCGACCTCTACGCCGG
CATCAAGGACCTGCCCATCGTCAGCCCGCACGGCCACACCGATCCGCGCTGGTATGCGCTGAACGAGCCGTTTCCGGATC
CGGCGCAACTGCTCATCGTGCCCGACCACTACATCTTCCGCATGCTGTTCAGCCAGGGCGTGCGGCTGGAGGATCTCGGC
GTGGCCAGCCTGGATGGCGCGCCGGTGGAAACAGACGGCCGAACGATCTGGCGGCGCTTCGCCGAGCATTATTACCTGTT
TCGCGGCACGCCGACCCGGTTGTGGTTCGACCATGTGCTGGCGCATCTGTTCGGCATCGAAGAGCCGCTGGATGCCACGA
CGGCCGACCGCCACTACGATACGATCGCGACGGTGCTGCAGTGGGAGAATTTCCGTCCGCGCGCCCTGTTCGAGCGCTTC
AACATCGAGGTCATCGCCACGACCGAAGGCGCGCTTGACGATCTCGAATGGCACAAAATGATCCGCGACAGCGGCTGGGA
GGGCCGCGTCGTCACCGCCTATCGGCCGGACGCGGTCGTCGATCCCGATTTCGAAGGGTTTTCGGCCAATCTCGACCGGC
TTGGCGAGATCACCGGCTGCGACACCGGCAGCTGGGCCGGTTACCTCGACGCGCATCGCCAGCGGCGCGCCTTCTTCAAG
AGTTTTGGCGCGACTTCGTCGGATCATGGCCATCCGACGGCGGAGACCGCCAATCTCTCCGACGCGGCGGCGCAGGAGCT
GTTCAACCGCATCCGCCGCGGCTCGCAGGATGAGCGCGAGCGCAAGCTGTTCCGCGCCCAGATGCTGACCGAGATGGCCA
AGATGAGCCGGGATGACGGGCTGGTGCTGCAGATACATCCCGGTTCCTGGCGCAATCATTCGCCTTCTGTCTTCCAGAGG
TTCGGCCGCGACAAGGGTTTCGATATCCCGACGCGGACCGATTATGTGACGGCGCTGAAGCCGCTGCTCGACTGCGTCGG
GCTGGAGCGTGACCTGACGGTGATCCTCTTCACGCTCGACGAGAGCAGCTACGCGCGCGAGCTGGCGCCGCTGGCCGGTG
TTTACCCGGCGTTGAAGCTCGGCCCCGCCTGGTGGTTCCACGACAGTCCGGAAGGCATGCGCCGGTTTCGCGAGATGACG
ACGGAGACGGCCGGCTTCTACAACACTGTCGGCTTCAACGACGACACGCGTGCCTTTCCCTCGATCCCGGCTCGCCATGA
CGTGGCGCGGCGAGTCGACTGTGCGTTCCTGGCGCGCCTCGTCGCCGAGCATCGGCTGCGCGAGGACGAGGCGCATGAGC
TGGCACGGGAATTGGCCCATACGCTGGCGAAAAAGGCGTACCGGCTTTGA

Upstream 100 bases:

>100_bases
CCTGTTTGCGCCTGCCGCAAGGATGCCGCTTTGCCAACGCACATTGACATCGCTCTGGCCCGAACGTACCGCTACCCAGA
CTGGAGGAGCCGCTTTCCCC

Downstream 100 bases:

>100_bases
TGGCGGCGGCTCAAGATCCCAACGGCGGCGGCTGTTGGATCAGCATGACAGGCTGACATGAACAGCACCGGCATCGATCT
CTCCGCCTTCAGCCTGGCCG

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MVALTDPDLLFPPEAHSRSLARDLYAGIKDLPIVSPHGHTDPRWYALNEPFPDPAQLLIVPDHYIFRMLFSQGVRLEDLG
VASLDGAPVETDGRTIWRRFAEHYYLFRGTPTRLWFDHVLAHLFGIEEPLDATTADRHYDTIATVLQWENFRPRALFERF
NIEVIATTEGALDDLEWHKMIRDSGWEGRVVTAYRPDAVVDPDFEGFSANLDRLGEITGCDTGSWAGYLDAHRQRRAFFK
SFGATSSDHGHPTAETANLSDAAAQELFNRIRRGSQDERERKLFRAQMLTEMAKMSRDDGLVLQIHPGSWRNHSPSVFQR
FGRDKGFDIPTRTDYVTALKPLLDCVGLERDLTVILFTLDESSYARELAPLAGVYPALKLGPAWWFHDSPEGMRRFREMT
TETAGFYNTVGFNDDTRAFPSIPARHDVARRVDCAFLARLVAEHRLREDEAHELARELAHTLAKKAYRL

Sequences:

>Translated_469_residues
MVALTDPDLLFPPEAHSRSLARDLYAGIKDLPIVSPHGHTDPRWYALNEPFPDPAQLLIVPDHYIFRMLFSQGVRLEDLG
VASLDGAPVETDGRTIWRRFAEHYYLFRGTPTRLWFDHVLAHLFGIEEPLDATTADRHYDTIATVLQWENFRPRALFERF
NIEVIATTEGALDDLEWHKMIRDSGWEGRVVTAYRPDAVVDPDFEGFSANLDRLGEITGCDTGSWAGYLDAHRQRRAFFK
SFGATSSDHGHPTAETANLSDAAAQELFNRIRRGSQDERERKLFRAQMLTEMAKMSRDDGLVLQIHPGSWRNHSPSVFQR
FGRDKGFDIPTRTDYVTALKPLLDCVGLERDLTVILFTLDESSYARELAPLAGVYPALKLGPAWWFHDSPEGMRRFREMT
TETAGFYNTVGFNDDTRAFPSIPARHDVARRVDCAFLARLVAEHRLREDEAHELARELAHTLAKKAYRL
>Mature_469_residues
MVALTDPDLLFPPEAHSRSLARDLYAGIKDLPIVSPHGHTDPRWYALNEPFPDPAQLLIVPDHYIFRMLFSQGVRLEDLG
VASLDGAPVETDGRTIWRRFAEHYYLFRGTPTRLWFDHVLAHLFGIEEPLDATTADRHYDTIATVLQWENFRPRALFERF
NIEVIATTEGALDDLEWHKMIRDSGWEGRVVTAYRPDAVVDPDFEGFSANLDRLGEITGCDTGSWAGYLDAHRQRRAFFK
SFGATSSDHGHPTAETANLSDAAAQELFNRIRRGSQDERERKLFRAQMLTEMAKMSRDDGLVLQIHPGSWRNHSPSVFQR
FGRDKGFDIPTRTDYVTALKPLLDCVGLERDLTVILFTLDESSYARELAPLAGVYPALKLGPAWWFHDSPEGMRRFREMT
TETAGFYNTVGFNDDTRAFPSIPARHDVARRVDCAFLARLVAEHRLREDEAHELARELAHTLAKKAYRL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=433, Percent_Identity=27.0207852193995, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_RHILO (Q98EW1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105020.1
- ProteinModelPortal:   Q98EW1
- SMR:   Q98EW1
- GeneID:   1227681
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4056
- NMPDR:   fig|266835.1.peg.3124
- HOGENOM:   HBG293306
- OMA:   AWAKTVP
- ProtClustDB:   PRK02925
- BRENDA:   5.3.1.12
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53526; Mature: 53526

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALTDPDLLFPPEAHSRSLARDLYAGIKDLPIVSPHGHTDPRWYALNEPFPDPAQLLIV
CCEECCCCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEE
PDHYIFRMLFSQGVRLEDLGVASLDGAPVETDGRTIWRRFAEHYYLFRGTPTRLWFDHVL
CHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHHH
AHLFGIEEPLDATTADRHYDTIATVLQWENFRPRALFERFNIEVIATTEGALDDLEWHKM
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEECCCCHHHHHHHHH
IRDSGWEGRVVTAYRPDAVVDPDFEGFSANLDRLGEITGCDTGSWAGYLDAHRQRRAFFK
HHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
SFGATSSDHGHPTAETANLSDAAAQELFNRIRRGSQDERERKLFRAQMLTEMAKMSRDDG
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LVLQIHPGSWRNHSPSVFQRFGRDKGFDIPTRTDYVTALKPLLDCVGLERDLTVILFTLD
EEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEC
ESSYARELAPLAGVYPALKLGPAWWFHDSPEGMRRFREMTTETAGFYNTVGFNDDTRAFP
CCHHHHHHHHHHHHCHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SIPARHDVARRVDCAFLARLVAEHRLREDEAHELARELAHTLAKKAYRL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVALTDPDLLFPPEAHSRSLARDLYAGIKDLPIVSPHGHTDPRWYALNEPFPDPAQLLIV
CCEECCCCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEE
PDHYIFRMLFSQGVRLEDLGVASLDGAPVETDGRTIWRRFAEHYYLFRGTPTRLWFDHVL
CHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHHH
AHLFGIEEPLDATTADRHYDTIATVLQWENFRPRALFERFNIEVIATTEGALDDLEWHKM
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEECCCCHHHHHHHHH
IRDSGWEGRVVTAYRPDAVVDPDFEGFSANLDRLGEITGCDTGSWAGYLDAHRQRRAFFK
HHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
SFGATSSDHGHPTAETANLSDAAAQELFNRIRRGSQDERERKLFRAQMLTEMAKMSRDDG
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LVLQIHPGSWRNHSPSVFQRFGRDKGFDIPTRTDYVTALKPLLDCVGLERDLTVILFTLD
EEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEC
ESSYARELAPLAGVYPALKLGPAWWFHDSPEGMRRFREMTTETAGFYNTVGFNDDTRAFP
CCHHHHHHHHHHHHCHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SIPARHDVARRVDCAFLARLVAEHRLREDEAHELARELAHTLAKKAYRL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968