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The map label for this gene is dapA [H]

Identifier: 13473396

GI number: 13473396

Start: 3183923

End: 3184858

Strand: Reverse

Name: dapA [H]

Synonym: mll3981

Alternate gene names: 13473396

Gene position: 3184858-3183923 (Counterclockwise)

Preceding gene: 13473398

Following gene: 13473395

Centisome position: 45.26

GC content: 65.17

Gene sequence:

>936_bases
ATGTGGACCGGAGTTTTCCCCGCCGTTACGACCAAATTCACCGCCGACGACCGGCTCGACCATGCCGAAATGGAGCGCTG
TTTCGGCCTGCAGATGGAGGCCGGCTGCGACGGCATCATCGTCTGCGGCTCGCTCGGCGAAGGGCCGATGCTGTCGCCTG
ACGAGAAGATCGAAGTGCTGAAGACCGCGCAGAAAGTCGCCGGCAAGAAGCCGGTGCTGCTGACCGTCAACGAAGCGGGC
ACCCGTGAGGCCGCCGCTATCGCCAGGCGCGCCGCCAGGGAGGGCGCCGATGGCCTGATGGTGGTGCCGAGCCCGATCTA
CCACACCAACGCGGAAGAGACGGTGGCTGCGCTGCGCGCGGTCGCCGAGGCCGGCGACCTGCCGGTGATGATCTACTCCA
ACCGGCTCGCCTATCGCGTCGACGTCACCGTCGACCAGATGGAGGAGCTGGCATCGGACAAGCGCTTCGTCGCCATCAAG
GAATCCTCCGACGACATCAGGCGCTCGACCGAGATCATCAACCGGCTTGGCGATCGCTACGATCTGTTCACCGGTGTCGA
CAATCTCGCCTTCGAAGCGCTGTCGGTCGGCGCCATCGGCTGGGTGGCCGGCCTGGTCACCGCCTTCCCGCGCGAAACCG
TTGCCATCTTCCAGCTGATGAAGCAGGGCCGCCGCGAGGAGGCGCTTGCCGTATACCGCTGGTTCCGGCCGCTGCTCGAT
CTCGACGTCTCGACCTATCTGGTACAGAACATCAAGCTTGCCGAAGTGCTGGCAATCGATACCAATGACCGCGTGCGCAT
GCCGCGCCAACCGTTGTCGGGCGAGCGCCGCAAGGCGGTCGAGAAGATCATACGGGATGCGCTGGCGGCGCGGCCGAAGC
TGCCGTCGCTCCAGACGTCTCCTCTATCGGCGGACAGACAGGTGGCAGCCGAATAA

Upstream 100 bases:

>100_bases
GCGATCTCCTGATATATCCCGAATATATCATAACGGATTCTGCATTGACAGCGGGCTTCTTAACAGATATACGGCTGATA
TATCAGATGGAGACGCGACC

Downstream 100 bases:

>100_bases
GGGACAGCACCGACGTGCCAGGAAATTCCGAATCCCCGGAACAGGAGCAGCGCTCGGCCGCTGGGGCACCTTCTCCCCGT
GAGCGGGGAGGAGGTGAGGA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MWTGVFPAVTTKFTADDRLDHAEMERCFGLQMEAGCDGIIVCGSLGEGPMLSPDEKIEVLKTAQKVAGKKPVLLTVNEAG
TREAAAIARRAAREGADGLMVVPSPIYHTNAEETVAALRAVAEAGDLPVMIYSNRLAYRVDVTVDQMEELASDKRFVAIK
ESSDDIRRSTEIINRLGDRYDLFTGVDNLAFEALSVGAIGWVAGLVTAFPRETVAIFQLMKQGRREEALAVYRWFRPLLD
LDVSTYLVQNIKLAEVLAIDTNDRVRMPRQPLSGERRKAVEKIIRDALAARPKLPSLQTSPLSADRQVAAE

Sequences:

>Translated_311_residues
MWTGVFPAVTTKFTADDRLDHAEMERCFGLQMEAGCDGIIVCGSLGEGPMLSPDEKIEVLKTAQKVAGKKPVLLTVNEAG
TREAAAIARRAAREGADGLMVVPSPIYHTNAEETVAALRAVAEAGDLPVMIYSNRLAYRVDVTVDQMEELASDKRFVAIK
ESSDDIRRSTEIINRLGDRYDLFTGVDNLAFEALSVGAIGWVAGLVTAFPRETVAIFQLMKQGRREEALAVYRWFRPLLD
LDVSTYLVQNIKLAEVLAIDTNDRVRMPRQPLSGERRKAVEKIIRDALAARPKLPSLQTSPLSADRQVAAE
>Mature_311_residues
MWTGVFPAVTTKFTADDRLDHAEMERCFGLQMEAGCDGIIVCGSLGEGPMLSPDEKIEVLKTAQKVAGKKPVLLTVNEAG
TREAAAIARRAAREGADGLMVVPSPIYHTNAEETVAALRAVAEAGDLPVMIYSNRLAYRVDVTVDQMEELASDKRFVAIK
ESSDDIRRSTEIINRLGDRYDLFTGVDNLAFEALSVGAIGWVAGLVTAFPRETVAIFQLMKQGRREEALAVYRWFRPLLD
LDVSTYLVQNIKLAEVLAIDTNDRVRMPRQPLSGERRKAVEKIIRDALAARPKLPSLQTSPLSADRQVAAE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=230, Percent_Identity=26.5217391304348, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1788823, Length=290, Percent_Identity=23.7931034482759, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786463, Length=286, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789620, Length=251, Percent_Identity=27.4900398406374, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082415, Length=228, Percent_Identity=24.5614035087719, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 34202; Mature: 34202

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTGVFPAVTTKFTADDRLDHAEMERCFGLQMEAGCDGIIVCGSLGEGPMLSPDEKIEVL
CCCCCCCHHHEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHH
KTAQKVAGKKPVLLTVNEAGTREAAAIARRAAREGADGLMVVPSPIYHTNAEETVAALRA
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHH
VAEAGDLPVMIYSNRLAYRVDVTVDQMEELASDKRFVAIKESSDDIRRSTEIINRLGDRY
HHHCCCCEEEEECCCEEEEEECCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCHH
DLFTGVDNLAFEALSVGAIGWVAGLVTAFPRETVAIFQLMKQGRREEALAVYRWFRPLLD
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LDVSTYLVQNIKLAEVLAIDTNDRVRMPRQPLSGERRKAVEKIIRDALAARPKLPSLQTS
CCHHHHHHHCCCEEHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PLSADRQVAAE
CCCCCHHHCCC
>Mature Secondary Structure
MWTGVFPAVTTKFTADDRLDHAEMERCFGLQMEAGCDGIIVCGSLGEGPMLSPDEKIEVL
CCCCCCCHHHEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHH
KTAQKVAGKKPVLLTVNEAGTREAAAIARRAAREGADGLMVVPSPIYHTNAEETVAALRA
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHH
VAEAGDLPVMIYSNRLAYRVDVTVDQMEELASDKRFVAIKESSDDIRRSTEIINRLGDRY
HHHCCCCEEEEECCCEEEEEECCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCHH
DLFTGVDNLAFEALSVGAIGWVAGLVTAFPRETVAIFQLMKQGRREEALAVYRWFRPLLD
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LDVSTYLVQNIKLAEVLAIDTNDRVRMPRQPLSGERRKAVEKIIRDALAARPKLPSLQTS
CCHHHHHHHCCCEEHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PLSADRQVAAE
CCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA