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The map label for this gene is serC [H]

Identifier: 13473320

GI number: 13473320

Start: 3112952

End: 3114127

Strand: Reverse

Name: serC [H]

Synonym: mll3876

Alternate gene names: 13473320

Gene position: 3114127-3112952 (Counterclockwise)

Preceding gene: 13473321

Following gene: 13473319

Centisome position: 44.26

GC content: 64.63

Gene sequence:

>1176_bases
ATGACGACGCATACGAAGCCCGGACTCCGTCCGGCAAATCCCAATTTCTCCTCAGGTCCTTGCGCAAAACGCCCCGGCTG
GTCGGTCGAGGCGCTGAAGAATGCCGCGCTCGGCCGTTCCCATCGCGCCAAGATCGGCAAGACCAAGCTCGAACAGGCGA
TCGAGCTGACGCGCGAAATCCTCCAGGTTCCTGCGGACCACCGCATCGGCATCGTGCCGGCGTCGGACACGGGCGCCGTC
GAGATGGCGCTGTGGTCGCTGCTCGGTGAGCGTGGTGTCGACATGGTCGCCTGGGAAAGTTTTGGCTCCGGCTGGGTCAC
CGACGTGGTCAAGCAGCTGAAGCTGCCCGACGTGCGCAAGCTCGAGGCCGGCTACGGCGAATTGCCGGATCTGGCCAAGA
TCGATTTCGACCGCGACGTGGTCTTCACCTGGAACGGCACGACCTCGGGCGTGCGCGTGCCGAACGGTGATTTCATTCCT
GCCGACCGCAAGGGCCTGACCATCTGCGACGCCACTTCGGCCGCGTTCGCGCAAAGGCTCGATTTCGAAAAGCTCGATGT
CGTCACTTTCTCCTGGCAGAAAGTGCTGGGCGGCGAGGGCGCGCATGGCATGCTGATCCTGTCGCCCCGCGCCGTTGCCC
GGCTGGAGAGCTACAAGCCTGCATGGCCGCTGCCGAAAATCTTCCGCCTGACCTCCGGCGGCAAGCTGATCGAGGGCATC
TTCAAGGGCGAGACCATCAACACGCCGTCGATGCTGTGCGTCGAGGATTATCTCGACGCGTTGCACTGGGCGAAGTCGAT
CGGCGGCCTCGATGTGCTGGTCGCCAGGGCGGATGCCAATGCTGCCGTGCTCGACGGGTTTGTCGACAAGTCCTCATGGC
TCGGCCATCTCGCCGTCCAGCCGGCGACGCGGTCGAACACATCAGTCTGCTTGTCCTTCACCGATCCCGATGTGGCGGCG
CTCGATGCCGACGGGCAGGCGACTTTCGCCAAGGGGCTGGTCTCGGCGCTCGACAAGGAAGGTGTCGCCTATGACATCGG
CTCCTATCGCGACGCGCCTCCCGGCCTGCGTATCTGGTGTGGCGCGACGGTCGAGACCTCCGATCTCGAAACGCTGCTGC
CCTGGCTCGATTGGGCCTTCGCCGCGCAAAAGGCGTCGCTGAAAGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
ACAAAAACTTTCCTCTTGACGCCCGAGGCCTGAACGCATATCGCCGTCCGTGGGCCACCCCTCCCCAACGAGGGGCCACT
ATCTGGAAGGATAGACCACG

Downstream 100 bases:

>100_bases
GACTTTCCGTGGCGGCCCGCGGGCCGCCCATTCCCGGATCAATCCCATTTCAAGGAGGCCGCCATGGCGCCCCGCGTACT
CGTCTCTGACAAACTCTCTC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTTHTKPGLRPANPNFSSGPCAKRPGWSVEALKNAALGRSHRAKIGKTKLEQAIELTREILQVPADHRIGIVPASDTGAV
EMALWSLLGERGVDMVAWESFGSGWVTDVVKQLKLPDVRKLEAGYGELPDLAKIDFDRDVVFTWNGTTSGVRVPNGDFIP
ADRKGLTICDATSAAFAQRLDFEKLDVVTFSWQKVLGGEGAHGMLILSPRAVARLESYKPAWPLPKIFRLTSGGKLIEGI
FKGETINTPSMLCVEDYLDALHWAKSIGGLDVLVARADANAAVLDGFVDKSSWLGHLAVQPATRSNTSVCLSFTDPDVAA
LDADGQATFAKGLVSALDKEGVAYDIGSYRDAPPGLRIWCGATVETSDLETLLPWLDWAFAAQKASLKAAA

Sequences:

>Translated_391_residues
MTTHTKPGLRPANPNFSSGPCAKRPGWSVEALKNAALGRSHRAKIGKTKLEQAIELTREILQVPADHRIGIVPASDTGAV
EMALWSLLGERGVDMVAWESFGSGWVTDVVKQLKLPDVRKLEAGYGELPDLAKIDFDRDVVFTWNGTTSGVRVPNGDFIP
ADRKGLTICDATSAAFAQRLDFEKLDVVTFSWQKVLGGEGAHGMLILSPRAVARLESYKPAWPLPKIFRLTSGGKLIEGI
FKGETINTPSMLCVEDYLDALHWAKSIGGLDVLVARADANAAVLDGFVDKSSWLGHLAVQPATRSNTSVCLSFTDPDVAA
LDADGQATFAKGLVSALDKEGVAYDIGSYRDAPPGLRIWCGATVETSDLETLLPWLDWAFAAQKASLKAAA
>Mature_390_residues
TTHTKPGLRPANPNFSSGPCAKRPGWSVEALKNAALGRSHRAKIGKTKLEQAIELTREILQVPADHRIGIVPASDTGAVE
MALWSLLGERGVDMVAWESFGSGWVTDVVKQLKLPDVRKLEAGYGELPDLAKIDFDRDVVFTWNGTTSGVRVPNGDFIPA
DRKGLTICDATSAAFAQRLDFEKLDVVTFSWQKVLGGEGAHGMLILSPRAVARLESYKPAWPLPKIFRLTSGGKLIEGIF
KGETINTPSMLCVEDYLDALHWAKSIGGLDVLVARADANAAVLDGFVDKSSWLGHLAVQPATRSNTSVCLSFTDPDVAAL
DADGQATFAKGLVSALDKEGVAYDIGSYRDAPPGLRIWCGATVETSDLETLLPWLDWAFAAQKASLKAAA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR006271
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 42027; Mature: 41896

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHTKPGLRPANPNFSSGPCAKRPGWSVEALKNAALGRSHRAKIGKTKLEQAIELTREI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LQVPADHRIGIVPASDTGAVEMALWSLLGERGVDMVAWESFGSGWVTDVVKQLKLPDVRK
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCHHH
LEAGYGELPDLAKIDFDRDVVFTWNGTTSGVRVPNGDFIPADRKGLTICDATSAAFAQRL
HHCCCCCCCCCCEECCCCCEEEEECCCCCCEECCCCCCCCCCCCCCEEECCHHHHHHHHC
DFEKLDVVTFSWQKVLGGEGAHGMLILSPRAVARLESYKPAWPLPKIFRLTSGGKLIEGI
CCCHHEEEEEEHHHHHCCCCCCEEEEECCHHHHHHHCCCCCCCCHHHEEECCCCHHHHHH
FKGETINTPSMLCVEDYLDALHWAKSIGGLDVLVARADANAAVLDGFVDKSSWLGHLAVQ
HCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEC
PATRSNTSVCLSFTDPDVAALDADGQATFAKGLVSALDKEGVAYDIGSYRDAPPGLRIWC
CCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEE
GATVETSDLETLLPWLDWAFAAQKASLKAAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTHTKPGLRPANPNFSSGPCAKRPGWSVEALKNAALGRSHRAKIGKTKLEQAIELTREI
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LQVPADHRIGIVPASDTGAVEMALWSLLGERGVDMVAWESFGSGWVTDVVKQLKLPDVRK
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCHHH
LEAGYGELPDLAKIDFDRDVVFTWNGTTSGVRVPNGDFIPADRKGLTICDATSAAFAQRL
HHCCCCCCCCCCEECCCCCEEEEECCCCCCEECCCCCCCCCCCCCCEEECCHHHHHHHHC
DFEKLDVVTFSWQKVLGGEGAHGMLILSPRAVARLESYKPAWPLPKIFRLTSGGKLIEGI
CCCHHEEEEEEHHHHHCCCCCCEEEEECCHHHHHHHCCCCCCCCHHHEEECCCCHHHHHH
FKGETINTPSMLCVEDYLDALHWAKSIGGLDVLVARADANAAVLDGFVDKSSWLGHLAVQ
HCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEC
PATRSNTSVCLSFTDPDVAALDADGQATFAKGLVSALDKEGVAYDIGSYRDAPPGLRIWC
CCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEE
GATVETSDLETLLPWLDWAFAAQKASLKAAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]