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The map label for this gene is purE [H]

Identifier: 13473268

GI number: 13473268

Start: 3057698

End: 3058195

Strand: Direct

Name: purE [H]

Synonym: mlr3809

Alternate gene names: 13473268

Gene position: 3057698-3058195 (Clockwise)

Preceding gene: 13473267

Following gene: 13473269

Centisome position: 43.46

GC content: 69.08

Gene sequence:

>498_bases
TTGAACGATCAACGCGCCGACGTCGCCATCATCATGGGCAGCCAGTCCGACTGGGCGACGATGCGCCAGGCGGCCGAAAC
GCTGGAGGCGCTGGGCGTCCCGCACAAACGGCTGATCATCTCGGCGCATCGCACGCCCGACCGGCTCTATGAATTCGCCA
AGGGCGCAAAGGCCGCCGGCTACAAGGTGATCATCGCCGGCGCCGGCGGTGCCGCGCACCTGCCCGGCATGACGGCGGCG
ATGACGCCGCTGCCGGTGTTCGGCGTGCCGGTGGAATCGAAGGCGCTGTCGGGGCAGGATTCGCTGCTCTCCATCGTCCA
GATGCCAGCCGGCATTCCTGTCGGGACATTGGCCATCGGCAAGGCGGGTGCGGCCAATGCGGCCCTGTTGGCAGCCGCCG
TGCTGGCGCTCAACGACGACAAGCTTGCCCAGCGCCTCGACGCCTGGCGCGCCTCGCAGACCGCCAAGGTCGCCGACGAA
CCGACGGACACGCCGTGA

Upstream 100 bases:

>100_bases
GGCTGGATTGTGGCCGTCGGTTGCCGCCGATGCCCGCATATCCTTGCGGCCCCGCGCGAATTCCGCTAAGGCGCGCCTTT
GTCGCCGGGGAGCAACAAGC

Downstream 100 bases:

>100_bases
GCCTGCCCGCCGGATCGACCATCGGCATTATCGGCGGCGGCCAGCTCGGCCGCATGCTGGCAATGGCCGCCGCCCGCCTC
GGTTATCGCACCATCGTGCT

Product: phosphoribosylaminoimidazole carboxylase I

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNDQRADVAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHRTPDRLYEFAKGAKAAGYKVIIAGAGGAAHLPGMTAA
MTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIGKAGAANAALLAAAVLALNDDKLAQRLDAWRASQTAKVADE
PTDTP

Sequences:

>Translated_165_residues
MNDQRADVAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHRTPDRLYEFAKGAKAAGYKVIIAGAGGAAHLPGMTAA
MTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIGKAGAANAALLAAAVLALNDDKLAQRLDAWRASQTAKVADE
PTDTP
>Mature_165_residues
MNDQRADVAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHRTPDRLYEFAKGAKAAGYKVIIAGAGGAAHLPGMTAA
MTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIGKAGAANAALLAAAVLALNDDKLAQRLDAWRASQTAKVADE
PTDTP

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=156, Percent_Identity=68.5897435897436, Blast_Score=179, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6324702, Length=150, Percent_Identity=52.6666666666667, Blast_Score=144, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16978; Mature: 16978

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDQRADVAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHRTPDRLYEFAKGAKAAG
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCHHHHHHHHCCCCCCC
YKVIIAGAGGAAHLPGMTAAMTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIG
EEEEEEECCCCCCCCCCCHHCCCCCEECCCCCCHHCCCHHHHHHHHHCCCCCCCCCEECC
KAGAANAALLAAAVLALNDDKLAQRLDAWRASQTAKVADEPTDTP
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDQRADVAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHRTPDRLYEFAKGAKAAG
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCHHHHHHHHCCCCCCC
YKVIIAGAGGAAHLPGMTAAMTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIG
EEEEEEECCCCCCCCCCCHHCCCCCEECCCCCCHHCCCHHHHHHHHHCCCCCCCCCEECC
KAGAANAALLAAAVLALNDDKLAQRLDAWRASQTAKVADEPTDTP
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]