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The map label for this gene is kdgR [H]

Identifier: 13473257

GI number: 13473257

Start: 3049635

End: 3050423

Strand: Reverse

Name: kdgR [H]

Synonym: mll3795

Alternate gene names: 13473257

Gene position: 3050423-3049635 (Counterclockwise)

Preceding gene: 13473264

Following gene: 13473255

Centisome position: 43.35

GC content: 65.02

Gene sequence:

>789_bases
ATGCAAGACGGTAATGCCTTGGCCGTTTCGGCCGACGAAAAGACGACGGCGTCCCGCGAGAAGGGCCTCAACCGGGTGCT
CGAGATCCTGGACTTTCTGCACACGACGCAGCGGGCGATCGGCATTGGCGACCTTGCCAAGGGGGTGAACGCACCCCGCT
CGACGACCTACACGCTGGTGCGGTCGCTGGTCGACGCCGGCCTGCTGGAAATGGCGGGCGACGGCAACCGCGTCTATTTC
GGCAAGAAGCTCTATCTCTATGGAATGGATTATGTGCGCTGCAACGACCTGCTGCGGCGCGGGCGCCAGGAGGTCGACCA
TCTGTCGCGCGAAACCGGCGAGACCTCGGAACTGTGCATGCTGCAGAGCGGCCGCTACACCATCGTCCATTCCAGCCCCG
GCACCAGGCCGTTCCGCATCAGCTCCGCCACCGGCCTGCAGATACCGCTGCCCTGGACCGCCTCCGGCCGGCTGCTTCTG
GCGGGGCTGGAGCGGGCCGAGGTCGAAGCCATGGTGTCGGAAGACGATCTCGTGCTGCCCGACGGACGCAAGCTGAGGCT
CGACGATTTCATCGACGACATCGCCAAGGCTAGGGTGACTGGCTACTGCGTCACCTCGGGCCTGGTCGATGCCTATACGA
AATGTCTTGCCGCCCCGGTCTTTTCAGCGCCGGGCAAGGTCGAGGCGACGATGTGCCTGGTTGTTCCGATCGACACGTCC
GAGGAGCGGACCGGCAGTCTCATCGGCCTGCTGCGTGATCGCGCCGGCAGGCTTTCGATCGGCGGATAG

Upstream 100 bases:

>100_bases
CATGCACAGGCAAGACACACGTCGGCGCTTCAAAGTGGTTGTCTCTTACAAGAGACGCATGTATCCTGTACAAGACAGAT
ACTAACACCAGGAATCGACA

Downstream 100 bases:

>100_bases
GGGAACGCGTTCAGGCGATGATGTCTGGAATGATCTTGTCTTCCAGCTTCATCAGCCGGTCCTTGAGCGCGAGCTTTTTC
TTTTTCATGCGCTGGATCTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MQDGNALAVSADEKTTASREKGLNRVLEILDFLHTTQRAIGIGDLAKGVNAPRSTTYTLVRSLVDAGLLEMAGDGNRVYF
GKKLYLYGMDYVRCNDLLRRGRQEVDHLSRETGETSELCMLQSGRYTIVHSSPGTRPFRISSATGLQIPLPWTASGRLLL
AGLERAEVEAMVSEDDLVLPDGRKLRLDDFIDDIAKARVTGYCVTSGLVDAYTKCLAAPVFSAPGKVEATMCLVVPIDTS
EERTGSLIGLLRDRAGRLSIGG

Sequences:

>Translated_262_residues
MQDGNALAVSADEKTTASREKGLNRVLEILDFLHTTQRAIGIGDLAKGVNAPRSTTYTLVRSLVDAGLLEMAGDGNRVYF
GKKLYLYGMDYVRCNDLLRRGRQEVDHLSRETGETSELCMLQSGRYTIVHSSPGTRPFRISSATGLQIPLPWTASGRLLL
AGLERAEVEAMVSEDDLVLPDGRKLRLDDFIDDIAKARVTGYCVTSGLVDAYTKCLAAPVFSAPGKVEATMCLVVPIDTS
EERTGSLIGLLRDRAGRLSIGG
>Mature_262_residues
MQDGNALAVSADEKTTASREKGLNRVLEILDFLHTTQRAIGIGDLAKGVNAPRSTTYTLVRSLVDAGLLEMAGDGNRVYF
GKKLYLYGMDYVRCNDLLRRGRQEVDHLSRETGETSELCMLQSGRYTIVHSSPGTRPFRISSATGLQIPLPWTASGRLLL
AGLERAEVEAMVSEDDLVLPDGRKLRLDDFIDDIAKARVTGYCVTSGLVDAYTKCLAAPVFSAPGKVEATMCLVVPIDTS
EERTGSLIGLLRDRAGRLSIGG

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=242, Percent_Identity=26.0330578512397, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786468, Length=215, Percent_Identity=25.1162790697674, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082359, Length=221, Percent_Identity=21.7194570135747, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28426; Mature: 28426

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDGNALAVSADEKTTASREKGLNRVLEILDFLHTTQRAIGIGDLAKGVNAPRSTTYTLV
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHH
RSLVDAGLLEMAGDGNRVYFGKKLYLYGMDYVRCNDLLRRGRQEVDHLSRETGETSELCM
HHHHHHHHHHHCCCCCEEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEE
LQSGRYTIVHSSPGTRPFRISSATGLQIPLPWTASGRLLLAGLERAEVEAMVSEDDLVLP
EECCCEEEEECCCCCCCEEEECCCCCEEECCCCCCCCEEEECCCHHHHHHEECCCCEECC
DGRKLRLDDFIDDIAKARVTGYCVTSGLVDAYTKCLAAPVFSAPGKVEATMCLVVPIDTS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCC
EERTGSLIGLLRDRAGRLSIGG
CCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQDGNALAVSADEKTTASREKGLNRVLEILDFLHTTQRAIGIGDLAKGVNAPRSTTYTLV
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHH
RSLVDAGLLEMAGDGNRVYFGKKLYLYGMDYVRCNDLLRRGRQEVDHLSRETGETSELCM
HHHHHHHHHHHCCCCCEEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEE
LQSGRYTIVHSSPGTRPFRISSATGLQIPLPWTASGRLLLAGLERAEVEAMVSEDDLVLP
EECCCEEEEECCCCCCCEEEECCCCCEEECCCCCCCCEEEECCCHHHHHHEECCCCEECC
DGRKLRLDDFIDDIAKARVTGYCVTSGLVDAYTKCLAAPVFSAPGKVEATMCLVVPIDTS
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCC
EERTGSLIGLLRDRAGRLSIGG
CCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]