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The map label for this gene is yomI [H]

Identifier: 13473253

GI number: 13473253

Start: 3046571

End: 3047692

Strand: Reverse

Name: yomI [H]

Synonym: mll3791

Alternate gene names: 13473253

Gene position: 3047692-3046571 (Counterclockwise)

Preceding gene: 13473254

Following gene: 13473252

Centisome position: 43.32

GC content: 64.08

Gene sequence:

>1122_bases
GTGGCGCGAAAAATATCCCGGCGTCGAGAACCTCAAGGTCGCGGTGATGGGCTGCATCGTCAACGGCCCGGGCGAATCCA
AGCATGCCGATATCGGCATTTCGCTGCCCGGCACCGGCGAGACGCCGACGGCGCCTGTCTTCGTCGACGGCAAGAAGGCG
GCGACGCTGCGCGGAACGTCGATCGCGGCGGATTTCGAGAAAATGGTCACCGACTATATCGAGCAGAGGTTTGGGCGCGG
CGGCAAAGCCGCGGCAGAGTAGACGAAATGCAGCGTTTCCTCAGGGTGACGCTGGTTCTGCTTTGCGGGCTGGCCTGGTC
GACGCTTGCCCAGGCGGATCCGCCGCAATCGGCCAAGCAGCGGCTGATCGACAAGGTCTGCAACCTGATCCAGGCCCACG
CCGACCAGAACGGCCTGCCCCGGGATTTCTTCGCGAGGCTGATCTGGAAGGAAAGCCGTTTCGATCCCAATGCCGTCAGC
CCCGTCGGCGCCGAAGGTATCGCCCAGTTCATGCCGGGCACCGCCAAGATGCGGGGCCTCGAAAACTCCTTCGACATCTA
CCAGGCGATCCCGGCGTCTGCGAAATATCTCGCCGAAATGAAAACCGGCTACGGCAATCTCGGCCTGGCAGCGGCCGCCT
ACAATGCCGGCGAAAGCCGGGTGTCGCGCTGGCTGGGCTCGGGCGGCTTCCTGCCGATGGAGACCGAGAGCTATGTCTTC
GACGTCATGGGCGAGCCGGTCGACAAGTTCACCGACCCAGCCTATGCCGGAAAAATCGAGCCGCTCGACGCCAAGACGGA
TTTTGCCGTCGCCTGCCGCAAACTGCCTGTCATCATGTCGCAGACCGTGGCGATGGCCTCGATCAACGTCAAACCATGGG
GCGTCCAGGTGGCCGGCAATTTCCGCCGCAGTGCTGCAATCAGCCAGTGGCTCAGGGTGAGGAGCCGGTTTCCGGCGCTG
CTTGCCGGCCATGATCCGGTGGTGAGCCGGGTGCGCACGCCAATCGGCCGGCGCGGCATCTATGCGGTCAGGATCGGGAT
CGACGATCGTGCCGCCGCCAATGTCATCTGCCAGAAATTGCAGAGCGTCGGCGGGGCCTGTGTGGTGGTGCGCAACCGGT
AG

Upstream 100 bases:

>100_bases
CGATCGTCGCCGCTTGTCCCGGCTGCGGCCGCACGACCTCCACCGTGTTCCAGGAGCTTGCCCAGAACATCCAGGCTGAT
CTGCGCAAGAACATGCCGGT

Downstream 100 bases:

>100_bases
CTCGATCCGGAGCCGTATAGTCTTTTTGTTGAGAGTTGTTGAGAGTTGCTCTGAAGCAGCGTCGAAGGTAAAAGCCAGGA
TAGTCCTGCTCAATGGCGTC

Product: transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MARKISRRREPQGRGDGLHRQRPGRIQACRYRHFAARHRRDADGACLRRRQEGGDAARNVDRGGFRENGHRLYRAEVWAR
RQSRGRVDEMQRFLRVTLVLLCGLAWSTLAQADPPQSAKQRLIDKVCNLIQAHADQNGLPRDFFARLIWKESRFDPNAVS
PVGAEGIAQFMPGTAKMRGLENSFDIYQAIPASAKYLAEMKTGYGNLGLAAAAYNAGESRVSRWLGSGGFLPMETESYVF
DVMGEPVDKFTDPAYAGKIEPLDAKTDFAVACRKLPVIMSQTVAMASINVKPWGVQVAGNFRRSAAISQWLRVRSRFPAL
LAGHDPVVSRVRTPIGRRGIYAVRIGIDDRAAANVICQKLQSVGGACVVVRNR

Sequences:

>Translated_373_residues
MARKISRRREPQGRGDGLHRQRPGRIQACRYRHFAARHRRDADGACLRRRQEGGDAARNVDRGGFRENGHRLYRAEVWAR
RQSRGRVDEMQRFLRVTLVLLCGLAWSTLAQADPPQSAKQRLIDKVCNLIQAHADQNGLPRDFFARLIWKESRFDPNAVS
PVGAEGIAQFMPGTAKMRGLENSFDIYQAIPASAKYLAEMKTGYGNLGLAAAAYNAGESRVSRWLGSGGFLPMETESYVF
DVMGEPVDKFTDPAYAGKIEPLDAKTDFAVACRKLPVIMSQTVAMASINVKPWGVQVAGNFRRSAAISQWLRVRSRFPAL
LAGHDPVVSRVRTPIGRRGIYAVRIGIDDRAAANVICQKLQSVGGACVVVRNR
>Mature_372_residues
ARKISRRREPQGRGDGLHRQRPGRIQACRYRHFAARHRRDADGACLRRRQEGGDAARNVDRGGFRENGHRLYRAEVWARR
QSRGRVDEMQRFLRVTLVLLCGLAWSTLAQADPPQSAKQRLIDKVCNLIQAHADQNGLPRDFFARLIWKESRFDPNAVSP
VGAEGIAQFMPGTAKMRGLENSFDIYQAIPASAKYLAEMKTGYGNLGLAAAAYNAGESRVSRWLGSGGFLPMETESYVFD
VMGEPVDKFTDPAYAGKIEPLDAKTDFAVACRKLPVIMSQTVAMASINVKPWGVQVAGNFRRSAAISQWLRVRSRFPALL
AGHDPVVSRVRTPIGRRGIYAVRIGIDDRAAANVICQKLQSVGGACVVVRNR

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 10 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR008258
- InterPro:   IPR016047
- InterPro:   IPR010090
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF10145 PhageMin_Tail; PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 41460; Mature: 41329

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKISRRREPQGRGDGLHRQRPGRIQACRYRHFAARHRRDADGACLRRRQEGGDAARNV
CCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCC
DRGGFRENGHRLYRAEVWARRQSRGRVDEMQRFLRVTLVLLCGLAWSTLAQADPPQSAKQ
CCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RLIDKVCNLIQAHADQNGLPRDFFARLIWKESRFDPNAVSPVGAEGIAQFMPGTAKMRGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHCC
ENSFDIYQAIPASAKYLAEMKTGYGNLGLAAAAYNAGESRVSRWLGSGGFLPMETESYVF
CCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHH
DVMGEPVDKFTDPAYAGKIEPLDAKTDFAVACRKLPVIMSQTVAMASINVKPWGVQVAGN
HHHCCCHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCC
FRRSAAISQWLRVRSRFPALLAGHDPVVSRVRTPIGRRGIYAVRIGIDDRAAANVICQKL
HHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHH
QSVGGACVVVRNR
HHCCCEEEEEECC
>Mature Secondary Structure 
ARKISRRREPQGRGDGLHRQRPGRIQACRYRHFAARHRRDADGACLRRRQEGGDAARNV
CCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCC
DRGGFRENGHRLYRAEVWARRQSRGRVDEMQRFLRVTLVLLCGLAWSTLAQADPPQSAKQ
CCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RLIDKVCNLIQAHADQNGLPRDFFARLIWKESRFDPNAVSPVGAEGIAQFMPGTAKMRGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHCC
ENSFDIYQAIPASAKYLAEMKTGYGNLGLAAAAYNAGESRVSRWLGSGGFLPMETESYVF
CCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHH
DVMGEPVDKFTDPAYAGKIEPLDAKTDFAVACRKLPVIMSQTVAMASINVKPWGVQVAGN
HHHCCCHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCC
FRRSAAISQWLRVRSRFPALLAGHDPVVSRVRTPIGRRGIYAVRIGIDDRAAANVICQKL
HHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHH
QSVGGACVVVRNR
HHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]