| Definition | Mesorhizobium loti MAFF303099 chromosome, complete genome. |
|---|---|
| Accession | NC_002678 |
| Length | 7,036,071 |
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The map label for this gene is gno [H]
Identifier: 13473248
GI number: 13473248
Start: 3041075
End: 3041830
Strand: Direct
Name: gno [H]
Synonym: mlr3785
Alternate gene names: 13473248
Gene position: 3041075-3041830 (Clockwise)
Preceding gene: 13473247
Following gene: 13473249
Centisome position: 43.22
GC content: 65.48
Gene sequence:
>756_bases ATGTCGGCCAATCTGTTCGATCTCAGCGGGCGCCAGGCGCTCGTAACCGGCTCGTCGCAAGGCATTGGGCTCGCTCTGGC CAAGGGGCTGGCGCAAGCCGGCGCAAGCGTGATCCTCAACGGCCGTGACACGGCGAAGCTCGCCGCCACGGCGGCGCAGA TCCCTGGAGCGCAAACGCTTGCCTTCGACGCGACCGAGCATGACGCCGTCCGTTCCGCGATCGACAATTTCGAGCTGTCA GGCGGACCGATCGACATATTGGTAAACAATGCCGGCATGCAGTTCCGCACGCCGCTCGAGGATTTTCCGGCCGATGCATT CGAGCGGCTGCTGCAGACCAATGTCGCCAGCGTCTTCCACGTCGGCCAGGCGGTCGCGCGCCACATGATCAGGCGGGGCC GCGGCAAGATCATCAACATCGCCTCCGTGCAGACAGCACTCGCCCGCCCCGGCATCGCCCCCTACACGGCGACAAAAGGC GCGGTCGGCAACCTGACCAAAGGCATGGCGACGGACTGGGCCAAACACGGCCTGCAATGCAACGCCATCGCCCCCGGTTA TTTCGACACGCCGCTCAATGCGGCCCTTGTCGCCGATCCGGCTTTCAGCGGCTGGCTCGAAAAGCGCACCCCGGCCGGCC GCTGGGGCAAGGTGGAGGAACTGGTCGGCGCCTGCGTGTTCCTGGCCTCCGACGCCTCGTCCTTCGTCAACGGCCATATC CTTTATGTCGACGGCGGCATCACCGCATCGATCTGA
Upstream 100 bases:
>100_bases GGCGCTGCTGAAGGAGGCTGCGACCTTCGTCGCGACGCGCAACAGTTGAGCGCGGGCCGCGACGTCGGCGCGGGTTGAGA CAAATGGGAGATCAGCTTCG
Downstream 100 bases:
>100_bases TCGCCGCGCCGCCGCGCGAACGAGCAATCCTGCCGGTCGCGCGAACGAAATCTTAATGTAAATGAAGCGTAATCCCGGTC GTTAAAATAATGCGTATGTG
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MSANLFDLSGRQALVTGSSQGIGLALAKGLAQAGASVILNGRDTAKLAATAAQIPGAQTLAFDATEHDAVRSAIDNFELS GGPIDILVNNAGMQFRTPLEDFPADAFERLLQTNVASVFHVGQAVARHMIRRGRGKIINIASVQTALARPGIAPYTATKG AVGNLTKGMATDWAKHGLQCNAIAPGYFDTPLNAALVADPAFSGWLEKRTPAGRWGKVEELVGACVFLASDASSFVNGHI LYVDGGITASI
Sequences:
>Translated_251_residues MSANLFDLSGRQALVTGSSQGIGLALAKGLAQAGASVILNGRDTAKLAATAAQIPGAQTLAFDATEHDAVRSAIDNFELS GGPIDILVNNAGMQFRTPLEDFPADAFERLLQTNVASVFHVGQAVARHMIRRGRGKIINIASVQTALARPGIAPYTATKG AVGNLTKGMATDWAKHGLQCNAIAPGYFDTPLNAALVADPAFSGWLEKRTPAGRWGKVEELVGACVFLASDASSFVNGHI LYVDGGITASI >Mature_250_residues SANLFDLSGRQALVTGSSQGIGLALAKGLAQAGASVILNGRDTAKLAATAAQIPGAQTLAFDATEHDAVRSAIDNFELSG GPIDILVNNAGMQFRTPLEDFPADAFERLLQTNVASVFHVGQAVARHMIRRGRGKIINIASVQTALARPGIAPYTATKGA VGNLTKGMATDWAKHGLQCNAIAPGYFDTPLNAALVADPAFSGWLEKRTPAGRWGKVEELVGACVFLASDASSFVNGHIL YVDGGITASI
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=35.2459016393443, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=32.9411764705882, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=30.6122448979592, Blast_Score=111, Evalue=8e-25, Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=34.8017621145374, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=33.6032388663968, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.5352697095436, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=30.2788844621514, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI20149619, Length=212, Percent_Identity=29.7169811320755, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=29.4354838709677, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=31.2820512820513, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=25.9109311740891, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=28.9855072463768, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=30.2681992337165, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723191, Length=211, Percent_Identity=29.3838862559242, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI209862901, Length=254, Percent_Identity=29.1338582677165, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI19923983, Length=254, Percent_Identity=29.1338582677165, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI226371731, Length=203, Percent_Identity=26.6009852216749, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4557649, Length=194, Percent_Identity=28.8659793814433, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503817, Length=193, Percent_Identity=27.979274611399, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=26.7206477732794, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=29.6875, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI83715985, Length=261, Percent_Identity=29.1187739463602, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI223718074, Length=197, Percent_Identity=30.4568527918782, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=28.110599078341, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI7657478, Length=204, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=49.2063492063492, Blast_Score=253, Evalue=7e-69, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=40.650406504065, Blast_Score=164, Evalue=5e-42, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=33.9920948616601, Blast_Score=147, Evalue=7e-37, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=35.9183673469388, Blast_Score=141, Evalue=4e-35, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=32.4, Blast_Score=117, Evalue=8e-28, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=33.7301587301587, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=34.0080971659919, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=35.2459016393443, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=32.0987654320988, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.4820717131474, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=30.952380952381, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787820, Length=175, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-13, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=34.5528455284553, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=32.9218106995885, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=33.0612244897959, Blast_Score=117, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=31.6602316602317, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=31.6205533596838, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=31.6981132075472, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=32.089552238806, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30.8, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=32.4110671936759, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=30.7392996108949, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=30.0380228136882, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.4182509505703, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=30.9701492537313, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=33.0677290836653, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=30.8270676691729, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=29.3436293436293, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=30.2681992337165, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=30.4511278195489, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=30.7116104868914, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30.3846153846154, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.5880149812734, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=30.6513409961686, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=28.1368821292776, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538182, Length=268, Percent_Identity=33.2089552238806, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=30.4182509505703, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.2134831460674, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=31.1284046692607, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=26.7015706806283, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=26.0204081632653, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI115534660, Length=190, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71997402, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI32563809, Length=197, Percent_Identity=24.3654822335025, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17507613, Length=197, Percent_Identity=24.3654822335025, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=26.9430051813472, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=22.5296442687747, Blast_Score=71, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=35.5102040816327, Blast_Score=131, Evalue=4e-31, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.136546184739, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=36.2139917695473, Blast_Score=120, Evalue=8e-28, Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=35.1239669421488, Blast_Score=119, Evalue=3e-27, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=33.0677290836653, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=33.4645669291339, Blast_Score=117, Evalue=8e-27, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=30.9644670050761, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=30.9644670050761, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.7708333333333, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=31.2252964426877, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.7708333333333, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24640442, Length=199, Percent_Identity=30.6532663316583, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI281364892, Length=266, Percent_Identity=24.812030075188, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=30.9236947791165, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=30.5699481865285, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI21358495, Length=230, Percent_Identity=26.5217391304348, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24641232, Length=197, Percent_Identity=30.9644670050761, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24584752, Length=192, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24581726, Length=195, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21355631, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 26057; Mature: 25926
Theoretical pI: Translated: 7.63; Mature: 7.63
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSANLFDLSGRQALVTGSSQGIGLALAKGLAQAGASVILNGRDTAKLAATAAQIPGAQTL CCCCEEECCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEE AFDATEHDAVRSAIDNFELSGGPIDILVNNAGMQFRTPLEDFPADAFERLLQTNVASVFH EECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCHHHCCHHHHHHHHHHHHHHHHH VGQAVARHMIRRGRGKIINIASVQTALARPGIAPYTATKGAVGNLTKGMATDWAKHGLQC HHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEE NAIAPGYFDTPLNAALVADPAFSGWLEKRTPAGRWGKVEELVGACVFLASDASSFVNGHI CEECCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCEE LYVDGGITASI EEECCCEEECC >Mature Secondary Structure SANLFDLSGRQALVTGSSQGIGLALAKGLAQAGASVILNGRDTAKLAATAAQIPGAQTL CCCEEECCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEE AFDATEHDAVRSAIDNFELSGGPIDILVNNAGMQFRTPLEDFPADAFERLLQTNVASVFH EECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCHHHCCHHHHHHHHHHHHHHHHH VGQAVARHMIRRGRGKIINIASVQTALARPGIAPYTATKGAVGNLTKGMATDWAKHGLQC HHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEE NAIAPGYFDTPLNAALVADPAFSGWLEKRTPAGRWGKVEELVGACVFLASDASSFVNGHI CEECCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCEE LYVDGGITASI EEECCCEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]