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The map label for this gene is pit [H]

Identifier: 13473138

GI number: 13473138

Start: 2934634

End: 2936244

Strand: Reverse

Name: pit [H]

Synonym: mll3637

Alternate gene names: 13473138

Gene position: 2936244-2934634 (Counterclockwise)

Preceding gene: 13473139

Following gene: 13473134

Centisome position: 41.73

GC content: 63.31

Gene sequence:

>1611_bases
ATGGTGGACGTAGTTTCTAGTGAAGCGGGCATTCCGAGACCGGATCATCCGCTGCACAGTTCGGGTAGCGCGAAGTGGTT
CCTGCCGGCCTTCGGCGTGCTGGTGCTCGTCGGCGTCGTTTATGTCGGCTACGCGCTCAGCCAGGATCTGGCCGAGGCCA
AGACCGTGCCGTGGATCCTGCTCGGCATCGCCTTGCTCATCGCGCTCGGCTTCGAATTCGTCAACGGCTTCCATGATACG
GCCAATGCGGTGGCGACGGTCATCTACACACGCTCCATGCCGGCCGAATTCGCTGTCATGTGGTCGGGTGCCTTCAATTT
CCTCGGGGTTCTCACTTCCAGCGGCGCGGTCGCTTTCGGTATCCTGTCGCTGCTGCCGGTCGAGCTGATCCTGCAGGTCG
GCTCGTCCTCCGGCTTTGCCATGGTGTTCGCGCTGCTCGTCGCCGCCATCCTGTGGAACCTCGGCACCTGGTTCCTCGGC
CTGCCGGCGTCGAGCTCACACACGATGGTCGGCTCGATCATCGGCGTCGGCCTCGCCAACCAGTTCATGGCGCCTGCCGG
CAGTGCCACCAGCGGTGTCGACTGGTCGCAGGCAACCAATGTCGGCATCACCTTGCTGGTGTCGCCGATCATCGGCTTCT
TCGCCGCGGCGATCTTGCTCTATGCGATGAAGCTGCTCGTCCGCAATCCGGCCCTCTACGAAGCACCGAAAGGCAACACG
CCGCCGCCATGGTGGATCCGTGGGCTGCTGATCTTCACCTGCACCGGCGTCAGCTTCGCGCACGGCTCCAACGATGGGCA
GAAAGGCATGGGCCTGATCATGCTGATCCTGATCGGTGTCGTGCCGACGGCCTTCGCGCTGAACCGGACGCCCGACATCA
ACTATCTCGAGGCCTACAAGGCGGCTTCGGTCAACGTCGAGACCGCGCTGGGCAAATATGTCAAGCCGGGAGTCACCGTC
ACCGATGCCAAGGATGCCAAGGCAGCCGTGCAGGATGCCGTGCGCACCCGGACCTGGAACGACCAGACGACGGCCGCGCT
GCAGACCTATATCCACAATACGACAGCGGGCCTGCAGCCCTATGCCACTGTCGACAACGTGCCGACCGATCTAGTCAGCA
ACGCCCGCAACGACATCTACCTGATCGGCGAGGCACTCAAGCTGATCGACAAGAAGAAGTTGCTGCCGATGGAGGCTGCC
GATCTCAAGGCGGTCACCGACTATCATAAGGCCGTCGACAACGCGACGAAGTTCATCCCGATCTGGGTTAAGGTCGCGGT
GGCGCTGGCGCTTGGCCTCGGCACCATGGTCGGCTGGAAACGCATCGTCGTCACGGTCGGCGAGAAGATCGGCAAGAGCC
ATCTGACCTATGGCCAGGGTGCCGCCGCCGAACTCGTCGCCATGGTGACCATCGGCATGGCCGACCGGCTCGGCCTGCCG
GTGTCGACCACCCATGTGCTGTCGTCCGGCGTCGCCGGAACGATGGCCGCCAATGGCTCGGGCCTGCAATGGTCGACGGT
GCGCAACCTGCTGCTGGCCTGGGTGTTGACCCTGCCGTGCTCGATCACGCTCGCCTTCGTGCTGTTCATCGTTTTCCGCC
AGGTGTTCTGA

Upstream 100 bases:

>100_bases
GATATCCCTCAGAGGTTGTGTTCGATATCGTCATACAGGGTTCATTGTGCGGACATAGCGTTCGTCCCGGTTCTTTGCTG
CAATGCAATAGGAGTGGGAC

Downstream 100 bases:

>100_bases
GCGTCAGCCCCTCGAAAGAACGGCGCCACCTGTGGCGCCGTTTCTCTTTGTCGGCCCATCCTGCGAAGACCAATGAAGGG
TCAGAGCGCGCGCCTTCCCA

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MVDVVSSEAGIPRPDHPLHSSGSAKWFLPAFGVLVLVGVVYVGYALSQDLAEAKTVPWILLGIALLIALGFEFVNGFHDT
ANAVATVIYTRSMPAEFAVMWSGAFNFLGVLTSSGAVAFGILSLLPVELILQVGSSSGFAMVFALLVAAILWNLGTWFLG
LPASSSHTMVGSIIGVGLANQFMAPAGSATSGVDWSQATNVGITLLVSPIIGFFAAAILLYAMKLLVRNPALYEAPKGNT
PPPWWIRGLLIFTCTGVSFAHGSNDGQKGMGLIMLILIGVVPTAFALNRTPDINYLEAYKAASVNVETALGKYVKPGVTV
TDAKDAKAAVQDAVRTRTWNDQTTAALQTYIHNTTAGLQPYATVDNVPTDLVSNARNDIYLIGEALKLIDKKKLLPMEAA
DLKAVTDYHKAVDNATKFIPIWVKVAVALALGLGTMVGWKRIVVTVGEKIGKSHLTYGQGAAAELVAMVTIGMADRLGLP
VSTTHVLSSGVAGTMAANGSGLQWSTVRNLLLAWVLTLPCSITLAFVLFIVFRQVF

Sequences:

>Translated_536_residues
MVDVVSSEAGIPRPDHPLHSSGSAKWFLPAFGVLVLVGVVYVGYALSQDLAEAKTVPWILLGIALLIALGFEFVNGFHDT
ANAVATVIYTRSMPAEFAVMWSGAFNFLGVLTSSGAVAFGILSLLPVELILQVGSSSGFAMVFALLVAAILWNLGTWFLG
LPASSSHTMVGSIIGVGLANQFMAPAGSATSGVDWSQATNVGITLLVSPIIGFFAAAILLYAMKLLVRNPALYEAPKGNT
PPPWWIRGLLIFTCTGVSFAHGSNDGQKGMGLIMLILIGVVPTAFALNRTPDINYLEAYKAASVNVETALGKYVKPGVTV
TDAKDAKAAVQDAVRTRTWNDQTTAALQTYIHNTTAGLQPYATVDNVPTDLVSNARNDIYLIGEALKLIDKKKLLPMEAA
DLKAVTDYHKAVDNATKFIPIWVKVAVALALGLGTMVGWKRIVVTVGEKIGKSHLTYGQGAAAELVAMVTIGMADRLGLP
VSTTHVLSSGVAGTMAANGSGLQWSTVRNLLLAWVLTLPCSITLAFVLFIVFRQVF
>Mature_536_residues
MVDVVSSEAGIPRPDHPLHSSGSAKWFLPAFGVLVLVGVVYVGYALSQDLAEAKTVPWILLGIALLIALGFEFVNGFHDT
ANAVATVIYTRSMPAEFAVMWSGAFNFLGVLTSSGAVAFGILSLLPVELILQVGSSSGFAMVFALLVAAILWNLGTWFLG
LPASSSHTMVGSIIGVGLANQFMAPAGSATSGVDWSQATNVGITLLVSPIIGFFAAAILLYAMKLLVRNPALYEAPKGNT
PPPWWIRGLLIFTCTGVSFAHGSNDGQKGMGLIMLILIGVVPTAFALNRTPDINYLEAYKAASVNVETALGKYVKPGVTV
TDAKDAKAAVQDAVRTRTWNDQTTAALQTYIHNTTAGLQPYATVDNVPTDLVSNARNDIYLIGEALKLIDKKKLLPMEAA
DLKAVTDYHKAVDNATKFIPIWVKVAVALALGLGTMVGWKRIVVTVGEKIGKSHLTYGQGAAAELVAMVTIGMADRLGLP
VSTTHVLSSGVAGTMAANGSGLQWSTVRNLLLAWVLTLPCSITLAFVLFIVFRQVF

Specific function: Low-affinity inorganic phosphate transport [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789907, Length=480, Percent_Identity=42.5, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1789360, Length=483, Percent_Identity=39.1304347826087, Blast_Score=335, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI25146401, Length=386, Percent_Identity=23.3160621761658, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 56677; Mature: 56677

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVVSSEAGIPRPDHPLHSSGSAKWFLPAFGVLVLVGVVYVGYALSQDLAEAKTVPWIL
CCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LGIALLIALGFEFVNGFHDTANAVATVIYTRSMPAEFAVMWSGAFNFLGVLTSSGAVAFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHCCCHHHHH
ILSLLPVELILQVGSSSGFAMVFALLVAAILWNLGTWFLGLPASSSHTMVGSIIGVGLAN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHH
QFMAPAGSATSGVDWSQATNVGITLLVSPIIGFFAAAILLYAMKLLVRNPALYEAPKGNT
HHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
PPPWWIRGLLIFTCTGVSFAHGSNDGQKGMGLIMLILIGVVPTAFALNRTPDINYLEAYK
CCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AASVNVETALGKYVKPGVTVTDAKDAKAAVQDAVRTRTWNDQTTAALQTYIHNTTAGLQP
HCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
YATVDNVPTDLVSNARNDIYLIGEALKLIDKKKLLPMEAADLKAVTDYHKAVDNATKFIP
CCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHH
IWVKVAVALALGLGTMVGWKRIVVTVGEKIGKSHLTYGQGAAAELVAMVTIGMADRLGLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
VSTTHVLSSGVAGTMAANGSGLQWSTVRNLLLAWVLTLPCSITLAFVLFIVFRQVF
CCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVDVVSSEAGIPRPDHPLHSSGSAKWFLPAFGVLVLVGVVYVGYALSQDLAEAKTVPWIL
CCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LGIALLIALGFEFVNGFHDTANAVATVIYTRSMPAEFAVMWSGAFNFLGVLTSSGAVAFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHCCCHHHHH
ILSLLPVELILQVGSSSGFAMVFALLVAAILWNLGTWFLGLPASSSHTMVGSIIGVGLAN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHH
QFMAPAGSATSGVDWSQATNVGITLLVSPIIGFFAAAILLYAMKLLVRNPALYEAPKGNT
HHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
PPPWWIRGLLIFTCTGVSFAHGSNDGQKGMGLIMLILIGVVPTAFALNRTPDINYLEAYK
CCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AASVNVETALGKYVKPGVTVTDAKDAKAAVQDAVRTRTWNDQTTAALQTYIHNTTAGLQP
HCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
YATVDNVPTDLVSNARNDIYLIGEALKLIDKKKLLPMEAADLKAVTDYHKAVDNATKFIP
CCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHH
IWVKVAVALALGLGTMVGWKRIVVTVGEKIGKSHLTYGQGAAAELVAMVTIGMADRLGLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
VSTTHVLSSGVAGTMAANGSGLQWSTVRNLLLAWVLTLPCSITLAFVLFIVFRQVF
CCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]