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The map label for this gene is accA

Identifier: 13473086

GI number: 13473086

Start: 2881354

End: 2882304

Strand: Direct

Name: accA

Synonym: mlr3576

Alternate gene names: 13473086

Gene position: 2881354-2882304 (Clockwise)

Preceding gene: 13473085

Following gene: 13473087

Centisome position: 40.95

GC content: 64.46

Gene sequence:

>951_bases
ATGTATAATTACCTCGATTTCGAAAAGCCGGTGCAGGATCTCGAGCTCAAGATCCTCGAGCTCAAGAAGCTTGCCGAGAA
TGGCGAGGCGGTCGATGTCGCCGATGAGATCACCAGGCTGGAGAAGCGTTCGCGCGACGCGCTGCGCGATCTCTACAAGG
CGCTGACGCCCTGGCAGAAGGTGCAGGTGGCCCGCCATTCCGACAGGCCGCACTGCGTCGACTACATCAAAGGCCTGTTC
AGCGACTTCACGCCGCTCGCCGGCGACCGCAATTTCGGCGAGGACCAGGCGATCGTCGGCGGTTTTGCCCGCTTCCGCGG
CGAGCCTGTCGCGATCATCGGCCAGGAGAAGGGCTCGGACACGACCAGCCGCCTGAGGCACAATTTCGGTTCGGTGCGCC
CGGAAGGCTACCGCAAGGCGGTCCGGCTGATGGAACTGGCCGACCGCTTCAAGATCCCGCTGTTGACGCTGGTCGACACG
GCGGGCGCCTATCCCGGCGTCGGCGCCGAGGAGCGCGGCCAGGCCGAAGCCATTGCCCGCTCGACCTCGGCCTGCCTCGC
ACTGAAAGTGCCGTCGATCTCGGTGGTCATCGGCGAAGGCGGTTCGGGCGGCGCCATCGCGATCGCCACCGCCAACCGCG
TCTATATGCTCGAACACGCCATCTATTCGGTGATTTCGCCGGAGGGGGCGGCCTCGATCCTGTGGCGCGACACCACGCGC
TCCAAGGACGCGGCGACCAATATGAAGATCACCGCGCAGGATCTTCTGGAACTGAAGATCATCGACGCCATCATCCCCGA
GCCGATGGGCGGTGCCCAGCGTGCGCCCGAAAAGGTGATTGCCGCGACCGGCGACCTCATTGCCAAGACGATGAAGGAAT
TCGCCGGCGCCAACACCGACTTCCGCGAACAGCGCCGCGAGAAATATCTGGCGATGGGCCGCAGCCTCTGA

Upstream 100 bases:

>100_bases
AGGCCTCATATCGCTATGTGAGGACGATATTTCACCGCCGGGAGCCTTGGTTTCAAGGGTTCCGCAGTCCTTGCCTTCCG
ACGTATCGGTCCGCTCAAGC

Downstream 100 bases:

>100_bases
CGGCATCTGCCGGTGGACAAGGCCATTGGAAGCCCCGCGCCCGCGGCAATGTGGCGGCAATGTGCAATTTCGCCACAAAA
ATGCCGCCGGATTCGGGTCA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYNYLDFEKPVQDLELKILELKKLAENGEAVDVADEITRLEKRSRDALRDLYKALTPWQKVQVARHSDRPHCVDYIKGLF
SDFTPLAGDRNFGEDQAIVGGFARFRGEPVAIIGQEKGSDTTSRLRHNFGSVRPEGYRKAVRLMELADRFKIPLLTLVDT
AGAYPGVGAEERGQAEAIARSTSACLALKVPSISVVIGEGGSGGAIAIATANRVYMLEHAIYSVISPEGAASILWRDTTR
SKDAATNMKITAQDLLELKIIDAIIPEPMGGAQRAPEKVIAATGDLIAKTMKEFAGANTDFREQRREKYLAMGRSL

Sequences:

>Translated_316_residues
MYNYLDFEKPVQDLELKILELKKLAENGEAVDVADEITRLEKRSRDALRDLYKALTPWQKVQVARHSDRPHCVDYIKGLF
SDFTPLAGDRNFGEDQAIVGGFARFRGEPVAIIGQEKGSDTTSRLRHNFGSVRPEGYRKAVRLMELADRFKIPLLTLVDT
AGAYPGVGAEERGQAEAIARSTSACLALKVPSISVVIGEGGSGGAIAIATANRVYMLEHAIYSVISPEGAASILWRDTTR
SKDAATNMKITAQDLLELKIIDAIIPEPMGGAQRAPEKVIAATGDLIAKTMKEFAGANTDFREQRREKYLAMGRSL
>Mature_316_residues
MYNYLDFEKPVQDLELKILELKKLAENGEAVDVADEITRLEKRSRDALRDLYKALTPWQKVQVARHSDRPHCVDYIKGLF
SDFTPLAGDRNFGEDQAIVGGFARFRGEPVAIIGQEKGSDTTSRLRHNFGSVRPEGYRKAVRLMELADRFKIPLLTLVDT
AGAYPGVGAEERGQAEAIARSTSACLALKVPSISVVIGEGGSGGAIAIATANRVYMLEHAIYSVISPEGAASILWRDTTR
SKDAATNMKITAQDLLELKIIDAIIPEPMGGAQRAPEKVIAATGDLIAKTMKEFAGANTDFREQRREKYLAMGRSL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=48.2649842271293, Blast_Score=307, Evalue=6e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_RHILO (Q98FX7)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104653.1
- ProteinModelPortal:   Q98FX7
- SMR:   Q98FX7
- GeneID:   1227314
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr3576
- NMPDR:   fig|266835.1.peg.2757
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34668; Mature: 34668

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNYLDFEKPVQDLELKILELKKLAENGEAVDVADEITRLEKRSRDALRDLYKALTPWQK
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VQVARHSDRPHCVDYIKGLFSDFTPLAGDRNFGEDQAIVGGFARFRGEPVAIIGQEKGSD
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
TTSRLRHNFGSVRPEGYRKAVRLMELADRFKIPLLTLVDTAGAYPGVGAEERGQAEAIAR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
STSACLALKVPSISVVIGEGGSGGAIAIATANRVYMLEHAIYSVISPEGAASILWRDTTR
HHCCEEEEECCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCC
SKDAATNMKITAQDLLELKIIDAIIPEPMGGAQRAPEKVIAATGDLIAKTMKEFAGANTD
CCHHHCCCEEEHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
FREQRREKYLAMGRSL
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYNYLDFEKPVQDLELKILELKKLAENGEAVDVADEITRLEKRSRDALRDLYKALTPWQK
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VQVARHSDRPHCVDYIKGLFSDFTPLAGDRNFGEDQAIVGGFARFRGEPVAIIGQEKGSD
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
TTSRLRHNFGSVRPEGYRKAVRLMELADRFKIPLLTLVDTAGAYPGVGAEERGQAEAIAR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
STSACLALKVPSISVVIGEGGSGGAIAIATANRVYMLEHAIYSVISPEGAASILWRDTTR
HHCCEEEEECCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCC
SKDAATNMKITAQDLLELKIIDAIIPEPMGGAQRAPEKVIAATGDLIAKTMKEFAGANTD
CCHHHCCCEEEHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
FREQRREKYLAMGRSL
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968