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The map label for this gene is etfA [H]

Identifier: 13473013

GI number: 13473013

Start: 2812438

End: 2813367

Strand: Direct

Name: etfA [H]

Synonym: mlr3488

Alternate gene names: 13473013

Gene position: 2812438-2813367 (Clockwise)

Preceding gene: 13473012

Following gene: 13473014

Centisome position: 39.97

GC content: 66.34

Gene sequence:

>930_bases
ATGGCAATTCTCCTCATCGCCGAACACGACAACGCCAGCCTTTCCGACCAGACCGCCAAGGCGCTTTCGGCGGCCCTGCA
GATCGGCTCGGACGTGCATGTGCTGGTGGCCGGCAAGGGCGCCAAGGGCGCGGCTGACGCCGCGGCCAAGCTCAAGGGCG
TGAGCAAGGTGCTGCTCGCCGAAGCCGACGAACTCGCCGAGCGTCTCGCCGAACCGACGGCAGCCCTCGTCGTGTCGCTC
GCCGGCGGCTACGACACCATCATCGCGCCGGCGACCTCGTCGGGCAAGAATGTCGCGCCGCGCGTGGCGGCCCTGCTCGA
TGTCGCGCAGGTCTCCGAGATCATCGAAGTGGTCTCGCCTGACACGTTCAAGCGGCCGATCTATGCCGGCAACGCCATCC
AGACCGTGCAGTCGACCGACACCAAGAAGGTCATCACCGTGCGCACAGCCTCCTTCCAGGCAGCGCCCGAGGGTGGCTCG
GCCGCGGTTGAGACCGTCAAGGCCGCGGCCAATCCGGGCCTGTCCACCTTCGTCGAGAACAAGCTGTCGGAGACCGACCG
TCCGGAACTGACCTCGGCCAAGATCATCATCTCCGGCGGCCGCGCGCTCGGCTCGTCGGAGAAGTTCCAGGAAGTCATCC
TGCCGGTCGCCGACAAGCTCGGTGCGGCGGTCGGCGCCTCGCGTGCCGCCGTCGATGCGGGCTATGCGCCGAACGATTGG
CAGGTCGGTCAGACCGGCAAGGTCGTCGCCCCCGATCTCTACATCGCGGTCGGCATCTCCGGCGCCATCCAGCACCTCGC
CGGCATGAAGGATTCCAAGGTCATCGTCGCCATCAACAAGGACGAAGAGGCTCCGATCTTCCAGGTTGCCGACTACGGCC
TCGTCGGCGATCTCTTCGTTATTCTGCCGGAGTTGCAGAAGGCGCTTTGA

Upstream 100 bases:

>100_bases
CCGCAAGGCGGGCGTCAAGGTCAAGAGCGTCGCCGAACTGGTCGACAAGCTCAAGAACGAAGCCGGCGTTTTGTAAACGA
TCGGGAAAGGAACAGACAAG

Downstream 100 bases:

>100_bases
CGCTCTCTGGCAAAGCGTATTAAATGCTTGGGGTGGGGTAGACGAAATCGCCCCGCCCTTTTAGTTTGCACCGCACAAAA
AGCAGGCTGCAAAAGCCTTT

Product: electron transfer flavoprotein alpha-subunit, (ETFLS)

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAILLIAEHDNASLSDQTAKALSAALQIGSDVHVLVAGKGAKGAADAAAKLKGVSKVLLAEADELAERLAEPTAALVVSL
AGGYDTIIAPATSSGKNVAPRVAALLDVAQVSEIIEVVSPDTFKRPIYAGNAIQTVQSTDTKKVITVRTASFQAAPEGGS
AAVETVKAAANPGLSTFVENKLSETDRPELTSAKIIISGGRALGSSEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFVILPELQKAL

Sequences:

>Translated_309_residues
MAILLIAEHDNASLSDQTAKALSAALQIGSDVHVLVAGKGAKGAADAAAKLKGVSKVLLAEADELAERLAEPTAALVVSL
AGGYDTIIAPATSSGKNVAPRVAALLDVAQVSEIIEVVSPDTFKRPIYAGNAIQTVQSTDTKKVITVRTASFQAAPEGGS
AAVETVKAAANPGLSTFVENKLSETDRPELTSAKIIISGGRALGSSEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFVILPELQKAL
>Mature_308_residues
AILLIAEHDNASLSDQTAKALSAALQIGSDVHVLVAGKGAKGAADAAAKLKGVSKVLLAEADELAERLAEPTAALVVSLA
GGYDTIIAPATSSGKNVAPRVAALLDVAQVSEIIEVVSPDTFKRPIYAGNAIQTVQSTDTKKVITVRTASFQAAPEGGSA
AVETVKAAANPGLSTFVENKLSETDRPELTSAKIIISGGRALGSSEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDWQ
VGQTGKVVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFVILPELQKAL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=309, Percent_Identity=54.0453074433657, Blast_Score=308, Evalue=6e-84,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=54.9090909090909, Blast_Score=281, Evalue=7e-76,
Organism=Escherichia coli, GI1786226, Length=233, Percent_Identity=34.7639484978541, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787990, Length=300, Percent_Identity=30.3333333333333, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082157, Length=229, Percent_Identity=30.5676855895196, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=309, Percent_Identity=53.3980582524272, Blast_Score=306, Evalue=9e-84,
Organism=Saccharomyces cerevisiae, GI6325261, Length=313, Percent_Identity=44.408945686901, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI17136898, Length=310, Percent_Identity=57.741935483871, Blast_Score=313, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24652801, Length=310, Percent_Identity=57.741935483871, Blast_Score=313, Evalue=7e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31584; Mature: 31453

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILLIAEHDNASLSDQTAKALSAALQIGSDVHVLVAGKGAKGAADAAAKLKGVSKVLLA
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EADELAERLAEPTAALVVSLAGGYDTIIAPATSSGKNVAPRVAALLDVAQVSEIIEVVSP
HHHHHHHHHHCCHHHHHEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DTFKRPIYAGNAIQTVQSTDTKKVITVRTASFQAAPEGGSAAVETVKAAANPGLSTFVEN
CCCCCCEECCCHHHHHHCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHCCCCHHHHHHH
KLSETDRPELTSAKIIISGGRALGSSEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFV
CCCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
ILPELQKAL
HHHHHHHCC
>Mature Secondary Structure 
AILLIAEHDNASLSDQTAKALSAALQIGSDVHVLVAGKGAKGAADAAAKLKGVSKVLLA
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EADELAERLAEPTAALVVSLAGGYDTIIAPATSSGKNVAPRVAALLDVAQVSEIIEVVSP
HHHHHHHHHHCCHHHHHEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DTFKRPIYAGNAIQTVQSTDTKKVITVRTASFQAAPEGGSAAVETVKAAANPGLSTFVEN
CCCCCCEECCCHHHHHHCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHCCCCHHHHHHH
KLSETDRPELTSAKIIISGGRALGSSEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFV
CCCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
ILPELQKAL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]