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The map label for this gene is grx [H]

Identifier: 13472984

GI number: 13472984

Start: 2785337

End: 2785606

Strand: Reverse

Name: grx [H]

Synonym: msl3452

Alternate gene names: 13472984

Gene position: 2785606-2785337 (Counterclockwise)

Preceding gene: 13472985

Following gene: 13472983

Centisome position: 39.59

GC content: 63.33

Gene sequence:

>270_bases
ATGGTCGATGTCACGATCTATACGCGCATGATGTGCGGCTACTGCACGGCAGCCAAGCGGCTGCTGGAGCGCAAGGGCGT
TGCCTATACCGAGCATGACGCTTCGTTTTCGCCGGAACTGCGCCAGGAGATGATCTCGCGCGCGCACGGCCGCACGACCT
TTCCGCAGATTTTCATCGGCGAGACGCATGTCGGCGGCTGCGACGATCTCCACGAGCTGGAGGCCGAAGGCCGGCTGGAC
AGGCTGCTCGCCAACGGCGCGACGATTTGA

Upstream 100 bases:

>100_bases
TCTGCCGTCGACGTGCTGACCTTCGCGCGTGTGTTGCCGGGGGACTTTCGGGCGGACGAGTCCGCGACTATATAAGTCGG
CAACGAAAGCGGAATTCATC

Downstream 100 bases:

>100_bases
GGGTATGATGATGGGTGTTTTCAAGGCTGCGGCGGTTCAGATGCGTTCCGGCGAAAGCCCCGAGCGCAACGCGGTCGATC
TCGAACGGCTGGTGCGTGAA

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MVDVTIYTRMMCGYCTAAKRLLERKGVAYTEHDASFSPELRQEMISRAHGRTTFPQIFIGETHVGGCDDLHELEAEGRLD
RLLANGATI

Sequences:

>Translated_89_residues
MVDVTIYTRMMCGYCTAAKRLLERKGVAYTEHDASFSPELRQEMISRAHGRTTFPQIFIGETHVGGCDDLHELEAEGRLD
RLLANGATI
>Mature_89_residues
MVDVTIYTRMMCGYCTAAKRLLERKGVAYTEHDASFSPELRQEMISRAHGRTTFPQIFIGETHVGGCDDLHELEAEGRLD
RLLANGATI

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=53.0120481927711, Blast_Score=86, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9974; Mature: 9974

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVTIYTRMMCGYCTAAKRLLERKGVAYTEHDASFSPELRQEMISRAHGRTTFPQIFIG
CCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEC
ETHVGGCDDLHELEAEGRLDRLLANGATI
CCCCCCCCHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure
MVDVTIYTRMMCGYCTAAKRLLERKGVAYTEHDASFSPELRQEMISRAHGRTTFPQIFIG
CCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEC
ETHVGGCDDLHELEAEGRLDRLLANGATI
CCCCCCCCHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]