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The map label for this gene is yafV [C]

Identifier: 13472983

GI number: 13472983

Start: 2784460

End: 2785326

Strand: Reverse

Name: yafV [C]

Synonym: mll3450

Alternate gene names: 13472983

Gene position: 2785326-2784460 (Counterclockwise)

Preceding gene: 13472984

Following gene: 13472982

Centisome position: 39.59

GC content: 66.32

Gene sequence:

>867_bases
ATGGGTGTTTTCAAGGCTGCGGCGGTTCAGATGCGTTCCGGCGAAAGCCCCGAGCGCAACGCGGTCGATCTCGAACGGCT
GGTGCGTGAAGCGGCCGGGCAGGGCGCGACCTATATCCAGACGCCGGAAATGACCGGGGCGCTGATCCGCGACAAGCAGG
CGCGTGCCGCTTCCTTCACCTCCGAAGACAAGGACATCATTGTTGCGACCGCACGCGGATTGGCGCGCGAACTCGGCGTC
TTCCTGCATATCGGCTCGACCGCCATCCTGCGCGCCGACGGCAAGCTCGCCAATCGGGCGCTGTTGTTCGGTCCGGACGG
CGCGACGCTCGCCACCTATGACAAAATCCACATGTTCGACGTCGATCTCGACAATGGCGAAAGCTGGCGCGAATCGGCTG
CCTACGAACCCGGCACCGAAGCCGTCGTGACCGAGGTAGCGGGCGCCAGACTGGGCTTTGCGGTCTGCTACGACCTGCGT
TTCCCGCAGCTGTTCCGCACCGAGGCGCTGGCCGGCGCGGATGTTTTGACCGTGCCCGCCGCCTTCACCCGGCAGACCGG
CGAGGCGCACTGGCATGTGTTGCTGAGAGCCCGCGCCATCGAGAACGGCGCCTTTGTCGTCGCCGCCGCGCAAGGCGGCC
TGCATGAGGACGGCCGCGAAACCTATGGCCATTCGTTGATCGTCGACCCGTGGGGGCGCGTCCTCGCCGAAGCCGCGCAT
GACGAGCCTGCGGTGGTCGTCGCCGAGATCGACCCGGCGCAGTCGCTTGCGGCGCGCAAGAAGATCCCCAATTTGAAGAA
TGCGCGGGATTTCACCATCAATGCCGGCGCGGTGGACGCGCCGCGTCTCAGGGGTGCCGCCTCTTGA

Upstream 100 bases:

>100_bases
GAGACGCATGTCGGCGGCTGCGACGATCTCCACGAGCTGGAGGCCGAAGGCCGGCTGGACAGGCTGCTCGCCAACGGCGC
GACGATTTGAGGGTATGATG

Downstream 100 bases:

>100_bases
TCCGCTTTTCCCTGATCTGCGAAAACGAACACGAGTTCGAGGGCTGGTTCCGCAGCAATGACGATTTCGACACCCAGAAG
AAGCGCGGCTTTGTCGATTG

Product: nitrilase, nitrilase 1 like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MGVFKAAAVQMRSGESPERNAVDLERLVREAAGQGATYIQTPEMTGALIRDKQARAASFTSEDKDIIVATARGLARELGV
FLHIGSTAILRADGKLANRALLFGPDGATLATYDKIHMFDVDLDNGESWRESAAYEPGTEAVVTEVAGARLGFAVCYDLR
FPQLFRTEALAGADVLTVPAAFTRQTGEAHWHVLLRARAIENGAFVVAAAQGGLHEDGRETYGHSLIVDPWGRVLAEAAH
DEPAVVVAEIDPAQSLAARKKIPNLKNARDFTINAGAVDAPRLRGAAS

Sequences:

>Translated_288_residues
MGVFKAAAVQMRSGESPERNAVDLERLVREAAGQGATYIQTPEMTGALIRDKQARAASFTSEDKDIIVATARGLARELGV
FLHIGSTAILRADGKLANRALLFGPDGATLATYDKIHMFDVDLDNGESWRESAAYEPGTEAVVTEVAGARLGFAVCYDLR
FPQLFRTEALAGADVLTVPAAFTRQTGEAHWHVLLRARAIENGAFVVAAAQGGLHEDGRETYGHSLIVDPWGRVLAEAAH
DEPAVVVAEIDPAQSLAARKKIPNLKNARDFTINAGAVDAPRLRGAAS
>Mature_287_residues
GVFKAAAVQMRSGESPERNAVDLERLVREAAGQGATYIQTPEMTGALIRDKQARAASFTSEDKDIIVATARGLARELGVF
LHIGSTAILRADGKLANRALLFGPDGATLATYDKIHMFDVDLDNGESWRESAAYEPGTEAVVTEVAGARLGFAVCYDLRF
PQLFRTEALAGADVLTVPAAFTRQTGEAHWHVLLRARAIENGAFVVAAAQGGLHEDGRETYGHSLIVDPWGRVLAEAAHD
EPAVVVAEIDPAQSLAARKKIPNLKNARDFTINAGAVDAPRLRGAAS

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=277, Percent_Identity=38.9891696750903, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI297632350, Length=277, Percent_Identity=38.9891696750903, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI297632348, Length=277, Percent_Identity=38.9891696750903, Blast_Score=165, Evalue=3e-41,
Organism=Homo sapiens, GI9910460, Length=273, Percent_Identity=32.967032967033, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI297632346, Length=191, Percent_Identity=36.1256544502618, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786412, Length=252, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=34.7014925373134, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6322335, Length=298, Percent_Identity=29.5302013422819, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323383, Length=274, Percent_Identity=31.7518248175182, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17933642, Length=266, Percent_Identity=36.0902255639098, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355835, Length=191, Percent_Identity=33.5078534031414, Blast_Score=128, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30742; Mature: 30611

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVFKAAAVQMRSGESPERNAVDLERLVREAAGQGATYIQTPEMTGALIRDKQARAASFT
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCHHHHHCCC
SEDKDIIVATARGLARELGVFLHIGSTAILRADGKLANRALLFGPDGATLATYDKIHMFD
CCCCCEEEEEHHHHHHHCCEEEEECCEEEEEECCCCCCEEEEECCCCCEEEEECEEEEEE
VDLDNGESWRESAAYEPGTEAVVTEVAGARLGFAVCYDLRFPQLFRTEALAGADVLTVPA
EECCCCCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCEEECCH
AFTRQTGEAHWHVLLRARAIENGAFVVAAAQGGLHEDGRETYGHSLIVDPWGRVLAEAAH
HHHCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCHHHHCCEEEECCHHHHHHHHCC
DEPAVVVAEIDPAQSLAARKKIPNLKNARDFTINAGAVDAPRLRGAAS
CCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
GVFKAAAVQMRSGESPERNAVDLERLVREAAGQGATYIQTPEMTGALIRDKQARAASFT
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCHHHHHCCC
SEDKDIIVATARGLARELGVFLHIGSTAILRADGKLANRALLFGPDGATLATYDKIHMFD
CCCCCEEEEEHHHHHHHCCEEEEECCEEEEEECCCCCCEEEEECCCCCEEEEECEEEEEE
VDLDNGESWRESAAYEPGTEAVVTEVAGARLGFAVCYDLRFPQLFRTEALAGADVLTVPA
EECCCCCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCEEECCH
AFTRQTGEAHWHVLLRARAIENGAFVVAAAQGGLHEDGRETYGHSLIVDPWGRVLAEAAH
HHHCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCHHHHCCEEEECCHHHHHHHHCC
DEPAVVVAEIDPAQSLAARKKIPNLKNARDFTINAGAVDAPRLRGAAS
CCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]