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The map label for this gene is ubiG

Identifier: 13472976

GI number: 13472976

Start: 2779219

End: 2779968

Strand: Direct

Name: ubiG

Synonym: mlr3442

Alternate gene names: 13472976

Gene position: 2779219-2779968 (Clockwise)

Preceding gene: 13472964

Following gene: 13472979

Centisome position: 39.5

GC content: 64.27

Gene sequence:

>750_bases
ATGCCAGAACCCCGACGATCGACGATCGATGCCGGAGAAGTCGAACGCTTTTCCGCCCTTGCTGCCGAATGGTGGAACCC
GAACGGCAAGTTTCGTCCGCTGCACAAGTTCAATCCGGTCCGGCTTTCCTATATCCGCGACCAGATAGCGGCGCGCTTCG
GCCGTGACCCGCGTGCCGCGCGGCCGTTCGAGGGGCTGCGCATCCTCGATATCGGCTGCGGCGGCGGTCTTTTGTGCGAG
CCGATGGCGCGGCTTGGCGCCGAGGTCGTGGGAGCGGATGCCTCCGAGACAAACATCGAAGTGGCGAAACTGCACGCGGC
CGAAGGCAATGTGATCGTCGACTACCGAGCCACGACGGCCGAGGATCTTGCCGACGCCGGCGAGACATTCGACGTCATCC
TCAACATGGAAGTGGTCGAGCACGTCGCCGACATCGACCTGTTCGTCGCCAAATGCGGGCAGATGGTCCGGCCCGGCGGC
ATCATGTTCGTGGCCACCATCAACCGCACGCTGAAGGCGCTCGGCCTGGCTATCATCGGCGCCGAATATGTGCTGCGCTG
GCTGCCGCGCGGCACCCACCAGTTCGGCAAGCTGGTGCGCCCGGAAGAACTGGAGAAGGCGCTCGGCGGCGCCAGCCTGA
CGATCATCGACCGCACCGGCGTCACCTACAATCCGCTTGCCGACCGTTGGGCGCGGTCGAAGGACATGGACGTCAATTAC
ATGGTGCTGGCGGAAAAGGGATCGGTCTGA

Upstream 100 bases:

>100_bases
ATGCCCTGACAGGATGTTTCGGCCTGTCGGCAGAGGAAAATTGTTGCCTTGACTTTCCCGCTCCCACGCCCGACTTCCTA
GCGTTCGAGGAGACCAACCA

Downstream 100 bases:

>100_bases
TCCGGCACACTTTTCCTGGAATTTGTTCCAAGGTGTGTTGAGATTCAGGTCAGGCCGAGTCGAAAATGGTGGCTTCCGAG
AACCGGAGCGGAGCGTACTT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MPEPRRSTIDAGEVERFSALAAEWWNPNGKFRPLHKFNPVRLSYIRDQIAARFGRDPRAARPFEGLRILDIGCGGGLLCE
PMARLGAEVVGADASETNIEVAKLHAAEGNVIVDYRATTAEDLADAGETFDVILNMEVVEHVADIDLFVAKCGQMVRPGG
IMFVATINRTLKALGLAIIGAEYVLRWLPRGTHQFGKLVRPEELEKALGGASLTIIDRTGVTYNPLADRWARSKDMDVNY
MVLAEKGSV

Sequences:

>Translated_249_residues
MPEPRRSTIDAGEVERFSALAAEWWNPNGKFRPLHKFNPVRLSYIRDQIAARFGRDPRAARPFEGLRILDIGCGGGLLCE
PMARLGAEVVGADASETNIEVAKLHAAEGNVIVDYRATTAEDLADAGETFDVILNMEVVEHVADIDLFVAKCGQMVRPGG
IMFVATINRTLKALGLAIIGAEYVLRWLPRGTHQFGKLVRPEELEKALGGASLTIIDRTGVTYNPLADRWARSKDMDVNY
MVLAEKGSV
>Mature_248_residues
PEPRRSTIDAGEVERFSALAAEWWNPNGKFRPLHKFNPVRLSYIRDQIAARFGRDPRAARPFEGLRILDIGCGGGLLCEP
MARLGAEVVGADASETNIEVAKLHAAEGNVIVDYRATTAEDLADAGETFDVILNMEVVEHVADIDLFVAKCGQMVRPGGI
MFVATINRTLKALGLAIIGAEYVLRWLPRGTHQFGKLVRPEELEKALGGASLTIIDRTGVTYNPLADRWARSKDMDVNYM
VLAEKGSV

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=248, Percent_Identity=39.1129032258064, Blast_Score=205, Evalue=2e-53,
Organism=Escherichia coli, GI1788564, Length=241, Percent_Identity=41.49377593361, Blast_Score=198, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI115533050, Length=249, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324476, Length=289, Percent_Identity=29.0657439446367, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281365311, Length=250, Percent_Identity=34, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585589, Length=212, Percent_Identity=36.7924528301887, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_RHILO (Q98G87)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104543.1
- ProteinModelPortal:   Q98G87
- GeneID:   1227204
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr3442
- NMPDR:   fig|266835.1.peg.2647
- HOGENOM:   HBG738842
- OMA:   GRMAPLH
- ProtClustDB:   PRK05134
- BRENDA:   2.1.1.64
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27319; Mature: 27188

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEPRRSTIDAGEVERFSALAAEWWNPNGKFRPLHKFNPVRLSYIRDQIAARFGRDPRAA
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
RPFEGLRILDIGCGGGLLCEPMARLGAEVVGADASETNIEVAKLHAAEGNVIVDYRATTA
CCCCCEEEEEECCCCCHHHHHHHHCCHHHCCCCCCCCCEEEEEEEECCCCEEEEEECCCH
EDLADAGETFDVILNMEVVEHVADIDLFVAKCGQMVRPGGIMFVATINRTLKALGLAIIG
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHH
AEYVLRWLPRGTHQFGKLVRPEELEKALGGASLTIIDRTGVTYNPLADRWARSKDMDVNY
HHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCEEEEEECCCCEECCHHHHHCCCCCCCCEE
MVLAEKGSV
EEEECCCCC
>Mature Secondary Structure 
PEPRRSTIDAGEVERFSALAAEWWNPNGKFRPLHKFNPVRLSYIRDQIAARFGRDPRAA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
RPFEGLRILDIGCGGGLLCEPMARLGAEVVGADASETNIEVAKLHAAEGNVIVDYRATTA
CCCCCEEEEEECCCCCHHHHHHHHCCHHHCCCCCCCCCEEEEEEEECCCCEEEEEECCCH
EDLADAGETFDVILNMEVVEHVADIDLFVAKCGQMVRPGGIMFVATINRTLKALGLAIIG
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHH
AEYVLRWLPRGTHQFGKLVRPEELEKALGGASLTIIDRTGVTYNPLADRWARSKDMDVNY
HHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCEEEEEECCCCEECCHHHHHCCCCCCCCEE
MVLAEKGSV
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968