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The map label for this gene is dgoD [H]

Identifier: 13472917

GI number: 13472917

Start: 2704775

End: 2705944

Strand: Direct

Name: dgoD [H]

Synonym: mlr3365

Alternate gene names: 13472917

Gene position: 2704775-2705944 (Clockwise)

Preceding gene: 13472916

Following gene: 13472918

Centisome position: 38.44

GC content: 65.98

Gene sequence:

>1170_bases
ATGCGTATCAAGACCGTCCAAGCCTGGTGGGTCCGCATCCCGATCGAAGCCGCTCGGCAGCACCGCAGCGACTTCGGTCA
GGTGACGACCTTCGACGCTGCCATCCTGCGCATCGAAACCGATGACGGACTGGTCGGCTGGGGTGAAGGCAAGAACGCAG
CCGGCAGCGCGGGCAGCTACGGCGCCCTCGTCCACCTGCTGAACCAGGAGGTCGGGCCGCAACTGATCGGCCGCGATCCG
GCCGATGTCGGCATCATCTGGGAAATGCTCTACAATGGCGTGCGCCATGACAGTGCCGCCCGCGCTGGCCACGCCATGCC
GCAACTGGCGCGCCGCGGCATGAGCATCGCCGCCATCAGCGCCGTCGACATCGCGCTTTGGGATATCCTGGGCAAGTCGC
TCGGCCAGCCGGTGTGGCGGCTGCTCGGCGGCCGCAAGATCGACCGCATGCAGGCCTACGCCTCGGGCGGCTGGGCGTCC
GCCGATGCCATCGGCGAGCAGTTGAAATCCTACATCGCCCGGGGCGGCTTCAAGGCGCTGAAGATGCGGGTCGGCGCCAT
GGATGGCGCGGCGCACGTCTCCGCTGCCCGTGTCCGCGCCGCGCGCCAGGCGCTTGGCCCCGATGTAGAGCTGATGGTGG
ACGCTCACGGCACCTATACGGTGGCGGAAGCCAAGCGCTTCATCCACCTCGTCAACGACCTCGATCTGGCCTGGTTCGAG
GAACCGGTGATCGCCGACGACAAGCCGGGCATGGCGGAAGTGCGCGCCTCCGGCGCCGTGCCGATCGCCACCGGCGAAAG
CGAGGCGACGCGCTATGCCTTCCGCGATCTTGCCGTGCTCAAGGCCGCCGACATCTTCCAGCCCGATCCCGCCTTTTGCG
GCGGCATCAGCGAAGCGATGAAGATCGGCACCATCGCCAGCGCCTTCAATCTGCGCTTTGCGCCGCATCTATGGGCCGGC
GCACCCTGCTTCTTCGCCGGGCTGCATGTCTGCGCCGCCTCGCCATCGAGTTTCACCGTCGAATATTCACTCGGCGCCAA
CCCGATGATCCACGATCTGATCGAAGAGACTGTCGAAGCACAGGACGGTATGATAGCGATCCCGGAAAAGCCCGGATTGG
GATTCACCGTTTCTGAGCGATTCCTGGAGGCGCACGCGCAACGCAATTGA

Upstream 100 bases:

>100_bases
TGCGCATCACCGCCGAAACGCTGCTGCCTCTGATCAAGTAGTCGACGACTGTTGGGAATTTGCCCTTTCGCCCTGACCGG
CGGCGGGGCTGGGGAAAGAC

Downstream 100 bases:

>100_bases
CGATGAAAGAAAAGAACCTTCTCGCGGAACTCGCAGCCTATCTGTTCTCCCACTCGGACAAGGAGAGCGGCCGCACCCCA
TCCGAACGTGAGCTGGCGGA

Product: hypothetical protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRIKTVQAWWVRIPIEAARQHRSDFGQVTTFDAAILRIETDDGLVGWGEGKNAAGSAGSYGALVHLLNQEVGPQLIGRDP
ADVGIIWEMLYNGVRHDSAARAGHAMPQLARRGMSIAAISAVDIALWDILGKSLGQPVWRLLGGRKIDRMQAYASGGWAS
ADAIGEQLKSYIARGGFKALKMRVGAMDGAAHVSAARVRAARQALGPDVELMVDAHGTYTVAEAKRFIHLVNDLDLAWFE
EPVIADDKPGMAEVRASGAVPIATGESEATRYAFRDLAVLKAADIFQPDPAFCGGISEAMKIGTIASAFNLRFAPHLWAG
APCFFAGLHVCAASPSSFTVEYSLGANPMIHDLIEETVEAQDGMIAIPEKPGLGFTVSERFLEAHAQRN

Sequences:

>Translated_389_residues
MRIKTVQAWWVRIPIEAARQHRSDFGQVTTFDAAILRIETDDGLVGWGEGKNAAGSAGSYGALVHLLNQEVGPQLIGRDP
ADVGIIWEMLYNGVRHDSAARAGHAMPQLARRGMSIAAISAVDIALWDILGKSLGQPVWRLLGGRKIDRMQAYASGGWAS
ADAIGEQLKSYIARGGFKALKMRVGAMDGAAHVSAARVRAARQALGPDVELMVDAHGTYTVAEAKRFIHLVNDLDLAWFE
EPVIADDKPGMAEVRASGAVPIATGESEATRYAFRDLAVLKAADIFQPDPAFCGGISEAMKIGTIASAFNLRFAPHLWAG
APCFFAGLHVCAASPSSFTVEYSLGANPMIHDLIEETVEAQDGMIAIPEKPGLGFTVSERFLEAHAQRN
>Mature_389_residues
MRIKTVQAWWVRIPIEAARQHRSDFGQVTTFDAAILRIETDDGLVGWGEGKNAAGSAGSYGALVHLLNQEVGPQLIGRDP
ADVGIIWEMLYNGVRHDSAARAGHAMPQLARRGMSIAAISAVDIALWDILGKSLGQPVWRLLGGRKIDRMQAYASGGWAS
ADAIGEQLKSYIARGGFKALKMRVGAMDGAAHVSAARVRAARQALGPDVELMVDAHGTYTVAEAKRFIHLVNDLDLAWFE
EPVIADDKPGMAEVRASGAVPIATGESEATRYAFRDLAVLKAADIFQPDPAFCGGISEAMKIGTIASAFNLRFAPHLWAG
APCFFAGLHVCAASPSSFTVEYSLGANPMIHDLIEETVEAQDGMIAIPEKPGLGFTVSERFLEAHAQRN

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=416, Percent_Identity=24.7596153846154, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI186972148, Length=329, Percent_Identity=24.9240121580547, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI48994953, Length=359, Percent_Identity=33.1476323119777, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1787864, Length=383, Percent_Identity=26.6318537859008, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI226510960, Length=304, Percent_Identity=28.2894736842105, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 41713; Mature: 41713

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKTVQAWWVRIPIEAARQHRSDFGQVTTFDAAILRIETDDGLVGWGEGKNAAGSAGSY
CCCEEEEEEEEECCHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEECCCCCCCCCCCCCH
GALVHLLNQEVGPQLIGRDPADVGIIWEMLYNGVRHDSAARAGHAMPQLARRGMSIAAIS
HHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHH
AVDIALWDILGKSLGQPVWRLLGGRKIDRMQAYASGGWASADAIGEQLKSYIARGGFKAL
HHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
KMRVGAMDGAAHVSAARVRAARQALGPDVELMVDAHGTYTVAEAKRFIHLVNDLDLAWFE
HHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHCCCHHHCC
EPVIADDKPGMAEVRASGAVPIATGESEATRYAFRDLAVLKAADIFQPDPAFCGGISEAM
CCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHH
KIGTIASAFNLRFAPHLWAGAPCFFAGLHVCAASPSSFTVEYSLGANPMIHDLIEETVEA
HHHHHHHHHHCEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
QDGMIAIPEKPGLGFTVSERFLEAHAQRN
CCCEEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIKTVQAWWVRIPIEAARQHRSDFGQVTTFDAAILRIETDDGLVGWGEGKNAAGSAGSY
CCCEEEEEEEEECCHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEECCCCCCCCCCCCCH
GALVHLLNQEVGPQLIGRDPADVGIIWEMLYNGVRHDSAARAGHAMPQLARRGMSIAAIS
HHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHH
AVDIALWDILGKSLGQPVWRLLGGRKIDRMQAYASGGWASADAIGEQLKSYIARGGFKAL
HHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
KMRVGAMDGAAHVSAARVRAARQALGPDVELMVDAHGTYTVAEAKRFIHLVNDLDLAWFE
HHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHCCCHHHCC
EPVIADDKPGMAEVRASGAVPIATGESEATRYAFRDLAVLKAADIFQPDPAFCGGISEAM
CCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHH
KIGTIASAFNLRFAPHLWAGAPCFFAGLHVCAASPSSFTVEYSLGANPMIHDLIEETVEA
HHHHHHHHHHCEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
QDGMIAIPEKPGLGFTVSERFLEAHAQRN
CCCEEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]