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The map label for this gene is zur [H]

Identifier: 13472869

GI number: 13472869

Start: 2651709

End: 2652179

Strand: Reverse

Name: zur [H]

Synonym: mll3299

Alternate gene names: 13472869

Gene position: 2652179-2651709 (Counterclockwise)

Preceding gene: 13472875

Following gene: 13472867

Centisome position: 37.69

GC content: 62.63

Gene sequence:

>471_bases
ATGGGATCAGGCGGTTTGCACGGGCAAACAGCCTGGAGATGGCGCAGGACAAGTTGGAACCGGACCATGGCGGCAAGGGA
TGTGCTGACGAAGAACCAGTTGTGCGTGCTCGAGAAGCTCGAGACCGCCAGCGGACCGCTCAGCGCCTACACCTTGCTTG
ACCAGTTGCGCGAGCGCGGTTTTCGCGCGCCGCTGCAGGTCTATCGCGCGCTCGACACGCTGGTGAAGTCCGGCTTCGTG
CACCGGCTGGAAAGCATCAATTCCTTCGTCGCTTGCGCCGAGCCGCATGATCACAGCCATTCGATGACCGCCTTCGCCAT
CTGCGACACCTGCGGGCAGGTGACCGAGATGTCGGATCACGATGTCGACCACCGGCTGAACGAATGGGTCCATTCGACGG
GCTTCGCCGCCAAGAAGGCGGTCATAGAATTTCGCGGGACGTGCGCGAAGTGCCGGGCCGAGGCTGCCTAA

Upstream 100 bases:

>100_bases
TGCCATCAAGCCTGCCGTCATCAAATGCGCCGGCACGTTATCGATGGGTCCGGGACAACAACAGAAAGAGTAGCAAAGAC
GACGGTTCGTCGCTATCTGA

Downstream 100 bases:

>100_bases
GCCTTCGCTTCGTCATACTAGGGCGAAGCAAGGAGCGAAGCGACGCGCGCAGACCCTAGTATCCATTCCGTGACATGGAC
GTGTTGCAGCGATGCAGACC

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MGSGGLHGQTAWRWRRTSWNRTMAARDVLTKNQLCVLEKLETASGPLSAYTLLDQLRERGFRAPLQVYRALDTLVKSGFV
HRLESINSFVACAEPHDHSHSMTAFAICDTCGQVTEMSDHDVDHRLNEWVHSTGFAAKKAVIEFRGTCAKCRAEAA

Sequences:

>Translated_156_residues
MGSGGLHGQTAWRWRRTSWNRTMAARDVLTKNQLCVLEKLETASGPLSAYTLLDQLRERGFRAPLQVYRALDTLVKSGFV
HRLESINSFVACAEPHDHSHSMTAFAICDTCGQVTEMSDHDVDHRLNEWVHSTGFAAKKAVIEFRGTCAKCRAEAA
>Mature_155_residues
GSGGLHGQTAWRWRRTSWNRTMAARDVLTKNQLCVLEKLETASGPLSAYTLLDQLRERGFRAPLQVYRALDTLVKSGFVH
RLESINSFVACAEPHDHSHSMTAFAICDTCGQVTEMSDHDVDHRLNEWVHSTGFAAKKAVIEFRGTCAKCRAEAA

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=134, Percent_Identity=42.5373134328358, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17420; Mature: 17289

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGGLHGQTAWRWRRTSWNRTMAARDVLTKNQLCVLEKLETASGPLSAYTLLDQLRERG
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
FRAPLQVYRALDTLVKSGFVHRLESINSFVACAEPHDHSHSMTAFAICDTCGQVTEMSDH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCC
DVDHRLNEWVHSTGFAAKKAVIEFRGTCAKCRAEAA
CHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
GSGGLHGQTAWRWRRTSWNRTMAARDVLTKNQLCVLEKLETASGPLSAYTLLDQLRERG
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
FRAPLQVYRALDTLVKSGFVHRLESINSFVACAEPHDHSHSMTAFAICDTCGQVTEMSDH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCC
DVDHRLNEWVHSTGFAAKKAVIEFRGTCAKCRAEAA
CHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]