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The map label for this gene is qor [C]

Identifier: 13472821

GI number: 13472821

Start: 2587581

End: 2588501

Strand: Direct

Name: qor [C]

Synonym: mlr3236

Alternate gene names: 13472821

Gene position: 2587581-2588501 (Clockwise)

Preceding gene: 13472819

Following gene: 13472831

Centisome position: 36.78

GC content: 68.4

Gene sequence:

>921_bases
ATGCTCGCCCTCACCATCTCTTCCGACAGCGCTGCCAGATTGAAACTCGCCGAAGTGGACGAGCCACAGCCTTGCGCGAA
CGAGGCTCTGGTCGCCGTCCACGCAACGTCGCTGAACCGCGGCGAACTGCGCCTGCTCACCATACGCCCGGACGGCTGGA
TACCCGGCCAGGACATCGTCGGGATCGTCGAACAGGCGGCAGCCGATGGCTCCGGGCCAGCCAAGGGCGCCCGCGTCGTG
GCTTTGGTCGACGAGGCCGGCTGGGCCGAACGTGTTGCCGTTCCGACCGACCGTCTCGCCGTCCTGCCGGATGAGGTCAG
CTTCGTTTCCGCCGCCACGCTCCCGGTGGCGGGCACGACGGCGCTGAGGACGTTGCGCCAAGGCGGTGACCTCGCCGGTC
AACGGGTACTGATCACCGGCGCAAGCGGCGCGGTCGGCCGTTTCCAGATCCAGATCGCCCGCGAACAAGGTGCCTCGGTG
ACCGCGGTCGCCGCCGCCCGGCATGCCGGGGATCTGCGCGATCTCGGAGCCGAGCAGGTCGTCGAGGCGATCGAGCTGGC
CGAGGGACCATTTTCGCTGATCACCGAGTCGGTCGGCGGCGAAAGCCTCGCCCGCGCGATCGAACGTGTCGCGCCCGGCG
GGACGATCGCCATGTTCGGTTCAAGCAGTGGCCAGCTCACGCCCATTGGCTTCCGCCAGTTCGTTCCGGGCCATGAGGGG
GCGAGGCTTCAGACCTTCGCCTACTACACCTCGGGCTTTGGCATTGGCGCCGATATTGCCGCGCTGCTCGCCCTGGTCGC
AGCCGGCCGGCTGGAAACCCGCGTCGCCTTGACCGTGCCGTGGACGGATATCGCCCAGGCTCTGGACGCACTGCGGCAGC
GCAGCTTCAGCGGCAAGGCTGTTCTCACCATGGCCGGATGA

Upstream 100 bases:

>100_bases
ATTGACCGCTTTTAGCGATCAATTGCCTTTACATCTAGATTATTCGTCAACGTAGATCGGTAGGCTCGGGTCGTTCTCGC
CAATTGGCCAAGGTGTACCC

Downstream 100 bases:

>100_bases
GCAATCCCGGCCGAAGTCGGCTTGCTCACACGTGCTGGCCGCCATTGATATGGATTTCCGAGCCGGTCACATAGGAGGCC
TGCTGCGAGCACAGGAAGAA

Product: oxidoreductase

Products: NADP(+); Semiquinone. [C]

Alternate protein names: Oxidoreductase; Alcohol Dehydrogenase GroES Domain Protein; Dehydrogenase; NADPHQuinone Reductase; Zinc-Containing Alcohol Dehydrogenase; Quinone Oxidoreductase; NAD(P)H Quinone Oxidoreductase PIG3 Family; Alcohol Dehydrogenase GroES-Like Domain Family; Alcohol Dehydrogenase GroES Domain-Containing Protein; Zn-Dependent Oxidoreductase NADPHQuinone Reductase; Alcohol Dehydrogenase Zinc-Containing; Zinc-Type Alcohol Dehydrogenase; NADPHQuinone Reductase Related Zn-Dependent Oxidoreductase; Alcohol Dehydrogenase GroES-Like Protein; Zinc-Containing Alcohol Dehydrogenase Superfamily Protein; NAD(P)H Quinone Oxidoreductase PIG3 Family Protein; Zinc-Dependent Oxidoreductase; Alcohol Dehydrogenase Superfamily Protein Zinc-Containing; NAD(P)H Quinone Oxidoreductase; Alcohol Dehydrogenase Related Protein; Zinc-Dependent NADPHQuinone Oxidoreductase; Alcohol Dehydrogenase And Quinone Oxidoreductase; Zn-Dependent Oxidoreductase NADphQuinone Reductase; Alcohol Dehydrogenase Zinc-Containing Protein; Alcohol Dehydrogenase Zinc Containing; NADPH Quinone Oxidoreductase

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLALTISSDSAARLKLAEVDEPQPCANEALVAVHATSLNRGELRLLTIRPDGWIPGQDIVGIVEQAAADGSGPAKGARVV
ALVDEAGWAERVAVPTDRLAVLPDEVSFVSAATLPVAGTTALRTLRQGGDLAGQRVLITGASGAVGRFQIQIAREQGASV
TAVAAARHAGDLRDLGAEQVVEAIELAEGPFSLITESVGGESLARAIERVAPGGTIAMFGSSSGQLTPIGFRQFVPGHEG
ARLQTFAYYTSGFGIGADIAALLALVAAGRLETRVALTVPWTDIAQALDALRQRSFSGKAVLTMAG

Sequences:

>Translated_306_residues
MLALTISSDSAARLKLAEVDEPQPCANEALVAVHATSLNRGELRLLTIRPDGWIPGQDIVGIVEQAAADGSGPAKGARVV
ALVDEAGWAERVAVPTDRLAVLPDEVSFVSAATLPVAGTTALRTLRQGGDLAGQRVLITGASGAVGRFQIQIAREQGASV
TAVAAARHAGDLRDLGAEQVVEAIELAEGPFSLITESVGGESLARAIERVAPGGTIAMFGSSSGQLTPIGFRQFVPGHEG
ARLQTFAYYTSGFGIGADIAALLALVAAGRLETRVALTVPWTDIAQALDALRQRSFSGKAVLTMAG
>Mature_306_residues
MLALTISSDSAARLKLAEVDEPQPCANEALVAVHATSLNRGELRLLTIRPDGWIPGQDIVGIVEQAAADGSGPAKGARVV
ALVDEAGWAERVAVPTDRLAVLPDEVSFVSAATLPVAGTTALRTLRQGGDLAGQRVLITGASGAVGRFQIQIAREQGASV
TAVAAARHAGDLRDLGAEQVVEAIELAEGPFSLITESVGGESLARAIERVAPGGTIAMFGSSSGQLTPIGFRQFVPGHEG
ARLQTFAYYTSGFGIGADIAALLALVAAGRLETRVALTVPWTDIAQALDALRQRSFSGKAVLTMAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24308257, Length=226, Percent_Identity=27.8761061946903, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI47519420, Length=328, Percent_Identity=25.9146341463415, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194239674, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=1e-10,
Organism=Homo sapiens, GI13236495, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 31480; Mature: 31480

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALTISSDSAARLKLAEVDEPQPCANEALVAVHATSLNRGELRLLTIRPDGWIPGQDIV
CEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHHH
GIVEQAAADGSGPAKGARVVALVDEAGWAERVAVPTDRLAVLPDEVSFVSAATLPVAGTT
HHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCEEECCCCCHHEEEECCCCCCHH
ALRTLRQGGDLAGQRVLITGASGAVGRFQIQIAREQGASVTAVAAARHAGDLRDLGAEQV
HHHHHHCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEHHHHHCCCHHHCCHHHH
VEAIELAEGPFSLITESVGGESLARAIERVAPGGTIAMFGSSSGQLTPIGFRQFVPGHEG
HHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCEEECCHHHCCCCCCC
ARLQTFAYYTSGFGIGADIAALLALVAAGRLETRVALTVPWTDIAQALDALRQRSFSGKA
CEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCE
VLTMAG
EEEECC
>Mature Secondary Structure
MLALTISSDSAARLKLAEVDEPQPCANEALVAVHATSLNRGELRLLTIRPDGWIPGQDIV
CEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHHH
GIVEQAAADGSGPAKGARVVALVDEAGWAERVAVPTDRLAVLPDEVSFVSAATLPVAGTT
HHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCEEECCCCCHHEEEECCCCCCHH
ALRTLRQGGDLAGQRVLITGASGAVGRFQIQIAREQGASVTAVAAARHAGDLRDLGAEQV
HHHHHHCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEHHHHHCCCHHHCCHHHH
VEAIELAEGPFSLITESVGGESLARAIERVAPGGTIAMFGSSSGQLTPIGFRQFVPGHEG
HHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCEEECCHHHCCCCCCC
ARLQTFAYYTSGFGIGADIAALLALVAAGRLETRVALTVPWTDIAQALDALRQRSFSGKA
CEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCE
VLTMAG
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.26 {1,4-naphthoquinone}} 0.065 {1,4-benzoquinone}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.0024 {1,2-naphthoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA