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The map label for this gene is rhtB [H]

Identifier: 13472782

GI number: 13472782

Start: 2553042

End: 2553656

Strand: Direct

Name: rhtB [H]

Synonym: mlr3188

Alternate gene names: 13472782

Gene position: 2553042-2553656 (Clockwise)

Preceding gene: 13472781

Following gene: 13472784

Centisome position: 36.29

GC content: 63.74

Gene sequence:

>615_bases
ATGTCGCTGGAACTCTATGCCGCTTATGTTCTCGCCTGCATCGTCATCATCCTGGTGCCGGGACCGACGGTCACACTGAT
CATCGCCAACAGCATCCGCCACGGAACCCGCGCCGGCCTCGCCAATGTCGCCGGCACGCAGGCCGGGCTTGCCATCATGA
TCGCCATTGTCGGCATCGGCCTCAACACGCTGATCGCGGGCATGGGCCACTGGTTTGAATGGGTCAGGCTGATCGGCGCC
GCCTATCTGATCTGGATGGGCGTGCAGATGTTCCGCTCCAAGGGCACGCTGAATGCCGACGGAACCGCTAGGAAGCCGCG
CGGCGGCTTCTTCCTGCAGGGCCTGCTGGTGGCGCTGAGCAATCCCAAGACCCTGGTGTTCTTCGGCGCCTTCTTCCCGC
AGTTCATCGCGCCGCAAGGCAACTATTCGCTGCAAATCGTCGTCATGGGCCTGACCGCCATGATCTTCGCCGCCATGTCG
GATTCGACCTACGCGCTCGCCGCCGGCCGCGCCGGACGCCTGCTGTCGGCCAGCCGCATCAAGCTCATGTCCAGGATCAG
CGGCAGCTTCTTGGTCGGTGGCGGCCTGTGGCTGGCGTTTTCGAGGTCGAAGTAA

Upstream 100 bases:

>100_bases
GCAACGGCGCGGTGTTTCGCGTCTGGCTTGCGCAGAGGCTACCACCATGCATTGATTGTCCCCTGCCACGCCGCATTGGC
GGGACTCCAAGGGAAAAACC

Downstream 100 bases:

>100_bases
CGCCTCTTCCTTCTCCCCTTGCGGGAGAAGGAAGATCGGCGCGCAGCGCCGAGACGGATGAGGGGAGCGTGACGGAGTGA
GGCGTTGGCGTTCCCTGGAT

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSLELYAAYVLACIVIILVPGPTVTLIIANSIRHGTRAGLANVAGTQAGLAIMIAIVGIGLNTLIAGMGHWFEWVRLIGA
AYLIWMGVQMFRSKGTLNADGTARKPRGGFFLQGLLVALSNPKTLVFFGAFFPQFIAPQGNYSLQIVVMGLTAMIFAAMS
DSTYALAAGRAGRLLSASRIKLMSRISGSFLVGGGLWLAFSRSK

Sequences:

>Translated_204_residues
MSLELYAAYVLACIVIILVPGPTVTLIIANSIRHGTRAGLANVAGTQAGLAIMIAIVGIGLNTLIAGMGHWFEWVRLIGA
AYLIWMGVQMFRSKGTLNADGTARKPRGGFFLQGLLVALSNPKTLVFFGAFFPQFIAPQGNYSLQIVVMGLTAMIFAAMS
DSTYALAAGRAGRLLSASRIKLMSRISGSFLVGGGLWLAFSRSK
>Mature_203_residues
SLELYAAYVLACIVIILVPGPTVTLIIANSIRHGTRAGLANVAGTQAGLAIMIAIVGIGLNTLIAGMGHWFEWVRLIGAA
YLIWMGVQMFRSKGTLNADGTARKPRGGFFLQGLLVALSNPKTLVFFGAFFPQFIAPQGNYSLQIVVMGLTAMIFAAMSD
STYALAAGRAGRLLSASRIKLMSRISGSFLVGGGLWLAFSRSK

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=204, Percent_Identity=37.2549019607843, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788099, Length=161, Percent_Identity=32.2981366459627, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI48994978, Length=214, Percent_Identity=28.0373831775701, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21630; Mature: 21499

Theoretical pI: Translated: 11.51; Mature: 11.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLELYAAYVLACIVIILVPGPTVTLIIANSIRHGTRAGLANVAGTQAGLAIMIAIVGIG
CCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCHHHHCCCHHHHHHHHHHHHHC
LNTLIAGMGHWFEWVRLIGAAYLIWMGVQMFRSKGTLNADGTARKPRGGFFLQGLLVALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NPKTLVFFGAFFPQFIAPQGNYSLQIVVMGLTAMIFAAMSDSTYALAAGRAGRLLSASRI
CCCEEEEEEHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
KLMSRISGSFLVGGGLWLAFSRSK
HHHHHCCCCEEEECEEEEEEECCC
>Mature Secondary Structure 
SLELYAAYVLACIVIILVPGPTVTLIIANSIRHGTRAGLANVAGTQAGLAIMIAIVGIG
CHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCHHHHCCCHHHHHHHHHHHHHC
LNTLIAGMGHWFEWVRLIGAAYLIWMGVQMFRSKGTLNADGTARKPRGGFFLQGLLVALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NPKTLVFFGAFFPQFIAPQGNYSLQIVVMGLTAMIFAAMSDSTYALAAGRAGRLLSASRI
CCCEEEEEEHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
KLMSRISGSFLVGGGLWLAFSRSK
HHHHHCCCCEEEECEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]