Click here to switch to the map view.

The map label for this gene is kdpE [H]

Identifier: 13472734

GI number: 13472734

Start: 2508134

End: 2508823

Strand: Reverse

Name: kdpE [H]

Synonym: mll3126

Alternate gene names: 13472734

Gene position: 2508823-2508134 (Counterclockwise)

Preceding gene: 13472735

Following gene: 13472725

Centisome position: 35.66

GC content: 60.29

Gene sequence:

>690_bases
ATGACAAACTCGAATGTCAGGATATTGGTTGTCGATGACGAGCCGCCGATCCGCAAGCTGCTTCGGGTCGGCCTTGGCAG
CCAGGGCTATGCGATCAGCGAGGCGCCGAACGCCAAGGTGGCGATCGAGCTGATGGAACAGGAAAAGCCGGATCTGGTGC
TGCTCGATCTCGGCCTGCCGGGCATGGGCGGCCATGAGCTCCTGCGCAAATGGCGGGACGAGGGTCTCGACATTCCCGTC
GTCATCCTCTCCAGCCGCACCGACGAGGCCGGCATCGTCAATGCGCTCGAGCTCGGTGCCGACGATTATGTCACCAAGCC
GTTCGGCATGAACGAACTGGTGGCGCGCATCCGCGTGGCGTTGCGGCACAAGTTCCAGCAACAGGGCGAAAAGCCTGTCT
TCCAGAGCGGCGATCTCAGCGTCGATCTGGTCAAGCGCATCGTCAAGGTCGAGGGCAAGGAGATAAAACTCTCGCCGAAG
GAATACGACATATTGCGCATCCTGGTGCAGCATGCCGGCAAGGTGCTGACCCACCATTTCATCCTGAAGCAGATCTGGGA
TGATTCGACCGACGTGCAGTATCTGCGGGTCTATGTCAGGCAGCTCCGGCAGAAGATCGAGAAGACCCCCGACCAGCCAC
GCTACATCACTACCGAGACCGGTGTCGGCTATCGGCTGCGTGTCGACTGA

Upstream 100 bases:

>100_bases
CCAACCGGACCGACCGCCCCGGTGCCGCGTTCACCATCAGGATGCCGGTGCCGACCGAAGCGCCCGATCGCGGCGAAGAG
ACCAGCATGGATCGGCCTTC

Downstream 100 bases:

>100_bases
GACAGCGCTCGATTGAACTCTTGTCAGCCGATGGCTTCCAGCGGCCGGTTTGCGGCCGCCGACGTCCGCAAGGCGGCGAG
ACAGCCGAGGATGCCAAGCG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTNSNVRILVVDDEPPIRKLLRVGLGSQGYAISEAPNAKVAIELMEQEKPDLVLLDLGLPGMGGHELLRKWRDEGLDIPV
VILSSRTDEAGIVNALELGADDYVTKPFGMNELVARIRVALRHKFQQQGEKPVFQSGDLSVDLVKRIVKVEGKEIKLSPK
EYDILRILVQHAGKVLTHHFILKQIWDDSTDVQYLRVYVRQLRQKIEKTPDQPRYITTETGVGYRLRVD

Sequences:

>Translated_229_residues
MTNSNVRILVVDDEPPIRKLLRVGLGSQGYAISEAPNAKVAIELMEQEKPDLVLLDLGLPGMGGHELLRKWRDEGLDIPV
VILSSRTDEAGIVNALELGADDYVTKPFGMNELVARIRVALRHKFQQQGEKPVFQSGDLSVDLVKRIVKVEGKEIKLSPK
EYDILRILVQHAGKVLTHHFILKQIWDDSTDVQYLRVYVRQLRQKIEKTPDQPRYITTETGVGYRLRVD
>Mature_228_residues
TNSNVRILVVDDEPPIRKLLRVGLGSQGYAISEAPNAKVAIELMEQEKPDLVLLDLGLPGMGGHELLRKWRDEGLDIPVV
ILSSRTDEAGIVNALELGADDYVTKPFGMNELVARIRVALRHKFQQQGEKPVFQSGDLSVDLVKRIVKVEGKEIKLSPKE
YDILRILVQHAGKVLTHHFILKQIWDDSTDVQYLRVYVRQLRQKIEKTPDQPRYITTETGVGYRLRVD

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=41.6666666666667, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.0807174887892, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=34.375, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.9285714285714, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=32.7586206896552, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=34.5291479820628, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=28.3783783783784, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=28.2608695652174, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=28.6919831223629, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.82096069869, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=36.8852459016393, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=29.4372294372294, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1790299, Length=161, Percent_Identity=29.8136645962733, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790437, Length=141, Percent_Identity=31.2056737588652, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI145693157, Length=109, Percent_Identity=33.9449541284404, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=36.6336633663366, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787473, Length=166, Percent_Identity=32.5301204819277, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25970; Mature: 25838

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNVRILVVDDEPPIRKLLRVGLGSQGYAISEAPNAKVAIELMEQEKPDLVLLDLGLP
CCCCCEEEEEECCCCHHHHHHHHCCCCCCCEECCCCCCEEEEEEHHCCCCCEEEEECCCC
GMGGHELLRKWRDEGLDIPVVILSSRTDEAGIVNALELGADDYVTKPFGMNELVARIRVA
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRHKFQQQGEKPVFQSGDLSVDLVKRIVKVEGKEIKLSPKEYDILRILVQHAGKVLTHHF
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
ILKQIWDDSTDVQYLRVYVRQLRQKIEKTPDQPRYITTETGVGYRLRVD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEC
>Mature Secondary Structure 
TNSNVRILVVDDEPPIRKLLRVGLGSQGYAISEAPNAKVAIELMEQEKPDLVLLDLGLP
CCCCEEEEEECCCCHHHHHHHHCCCCCCCEECCCCCCEEEEEEHHCCCCCEEEEECCCC
GMGGHELLRKWRDEGLDIPVVILSSRTDEAGIVNALELGADDYVTKPFGMNELVARIRVA
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRHKFQQQGEKPVFQSGDLSVDLVKRIVKVEGKEIKLSPKEYDILRILVQHAGKVLTHHF
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
ILKQIWDDSTDVQYLRVYVRQLRQKIEKTPDQPRYITTETGVGYRLRVD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]