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The map label for this gene is soxB [H]

Identifier: 13472725

GI number: 13472725

Start: 2500591

End: 2501844

Strand: Reverse

Name: soxB [H]

Synonym: mll3111

Alternate gene names: 13472725

Gene position: 2501844-2500591 (Counterclockwise)

Preceding gene: 13472734

Following gene: 13472724

Centisome position: 35.56

GC content: 64.35

Gene sequence:

>1254_bases
TTGAAAAAATATTCGGTATTCGCCATCGCCCGCGAGGCCATGCGCGGCCACAAGGGCTGGGAGGAACAATGGTCCTCGCC
TGAGCCCAAGAAGGAATACGACGTCATCATCGTCGGCGCCGGTGGCCATGGCCTGGCCACCGCCTATTATCTTGCCACGG
TGCATGGCATCACCAATGTCGCGGTGCTGGAAAAGGGCTGGCTGGGCGGCGGCAACACCGGCCGCAACACCACCATCATC
CGCTCCAACTATCTCTATGACGAGAGCGCCGGCATTTACGACCATGCGCTGAAGCTGTGGGATGGGCTCTCCCAGGAGCT
CAATTACAACGTCATGTATTCGGCGCGCGGCGTCATGATGCTTGCCCACAATGTGCATGACATCCAGGTGCTGAAGCGCC
ATGTCCACGCCAACCGGCTGAACGGCATCGACAATGAATGGCTGTCGCCGGAGCAGGCCAAAGAATTCTGCCCGCCGCTC
AACGTCTCCAGGGATGCACGCTATCCCGTCGTCGGTGCGGCGCTGCAGCGCCGCGGCGGCACGGCGCGCCACGATGCTGT
GGCCTGGGGCTATGCGCGCGGCGCCTCGGCGCGCGGCGTCCACATCATCCAGAATTGCGAGGTCACCGGCGTCAAGCGGG
CGGCCAATGGTGCGGTCATGGGCGTCGACACGACGCGCGGCTTCATCGGCGCCAAGAAGGTCGGCGTGGTTGCCGCCGGC
CATTCCTCGGTCATCATGAACATGGCCGGCGTGCGCATGCCGCTGGAAAGCTATCCGCTGCAGGCGCTGGTGTCGGAGCC
GGTCAAGCCGGTGGTGCCATGTGTGGTCATGTCCAACACGGTGCACGCCTATATCTCGCAGTCCGACAAGGGCGAGCTGG
TGATCGGCGCCGGCACCGATCAGTATGTCTCCTATTCGCAGACCGGTGGCTTGCACATTCTGCAGCATACGCTGGACGCC
ATCTGCGAGATGTTCCCGATCTTCACGCGCATGAAGATGCTGCGCTCCTGGGGCGGCATCGTCGACGTGACGCCCGACCG
CTCGCCGATCCTGGCCAAGACGCCGGTGCCCGGCCTCTACGTCAATTGCGGCTGGGGTACGGGCGGCTTCAAGGCGACGC
CGGGTTCGGGCCATGTCTTTGCCCACACCATCGCCAGGGACGATCCGCATCCGATCAACGCGCCCTTCACCATCGAACGC
TTCCGCACCGGCCGGCTGATCGACGAGGCGGCGGCGGCGGCAGTGGCGCACTGA

Upstream 100 bases:

>100_bases
AAGGGTGGAAGCGCTGTTTCGCTAGTGATACACCTCGCGCGCCGGGCCGAACAAAAGCCCGGCTGCAATCCGCGAGATCT
GTTGGCGCGAGGCTGGGACG

Downstream 100 bases:

>100_bases
TGATGGCGCAGATGGCTGTCGCGATGCCGCTGATGCTGGCGGGGGAACAAGGCATGTTCCACATGCCGTCGGCTGAAGAG
GTGCGGCTGCAGCCGATCAC

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKKYSVFAIAREAMRGHKGWEEQWSSPEPKKEYDVIIVGAGGHGLATAYYLATVHGITNVAVLEKGWLGGGNTGRNTTII
RSNYLYDESAGIYDHALKLWDGLSQELNYNVMYSARGVMMLAHNVHDIQVLKRHVHANRLNGIDNEWLSPEQAKEFCPPL
NVSRDARYPVVGAALQRRGGTARHDAVAWGYARGASARGVHIIQNCEVTGVKRAANGAVMGVDTTRGFIGAKKVGVVAAG
HSSVIMNMAGVRMPLESYPLQALVSEPVKPVVPCVVMSNTVHAYISQSDKGELVIGAGTDQYVSYSQTGGLHILQHTLDA
ICEMFPIFTRMKMLRSWGGIVDVTPDRSPILAKTPVPGLYVNCGWGTGGFKATPGSGHVFAHTIARDDPHPINAPFTIER
FRTGRLIDEAAAAAVAH

Sequences:

>Translated_417_residues
MKKYSVFAIAREAMRGHKGWEEQWSSPEPKKEYDVIIVGAGGHGLATAYYLATVHGITNVAVLEKGWLGGGNTGRNTTII
RSNYLYDESAGIYDHALKLWDGLSQELNYNVMYSARGVMMLAHNVHDIQVLKRHVHANRLNGIDNEWLSPEQAKEFCPPL
NVSRDARYPVVGAALQRRGGTARHDAVAWGYARGASARGVHIIQNCEVTGVKRAANGAVMGVDTTRGFIGAKKVGVVAAG
HSSVIMNMAGVRMPLESYPLQALVSEPVKPVVPCVVMSNTVHAYISQSDKGELVIGAGTDQYVSYSQTGGLHILQHTLDA
ICEMFPIFTRMKMLRSWGGIVDVTPDRSPILAKTPVPGLYVNCGWGTGGFKATPGSGHVFAHTIARDDPHPINAPFTIER
FRTGRLIDEAAAAAVAH
>Mature_417_residues
MKKYSVFAIAREAMRGHKGWEEQWSSPEPKKEYDVIIVGAGGHGLATAYYLATVHGITNVAVLEKGWLGGGNTGRNTTII
RSNYLYDESAGIYDHALKLWDGLSQELNYNVMYSARGVMMLAHNVHDIQVLKRHVHANRLNGIDNEWLSPEQAKEFCPPL
NVSRDARYPVVGAALQRRGGTARHDAVAWGYARGASARGVHIIQNCEVTGVKRAANGAVMGVDTTRGFIGAKKVGVVAAG
HSSVIMNMAGVRMPLESYPLQALVSEPVKPVVPCVVMSNTVHAYISQSDKGELVIGAGTDQYVSYSQTGGLHILQHTLDA
ICEMFPIFTRMKMLRSWGGIVDVTPDRSPILAKTPVPGLYVNCGWGTGGFKATPGSGHVFAHTIARDDPHPINAPFTIER
FRTGRLIDEAAAAAVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=395, Percent_Identity=25.5696202531646, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI21361378, Length=395, Percent_Identity=25.5696202531646, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI194306651, Length=385, Percent_Identity=24.4155844155844, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130091, Length=385, Percent_Identity=23.1168831168831, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45162; Mature: 45162

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYSVFAIAREAMRGHKGWEEQWSSPEPKKEYDVIIVGAGGHGLATAYYLATVHGITNV
CCCEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEE
AVLEKGWLGGGNTGRNTTIIRSNYLYDESAGIYDHALKLWDGLSQELNYNVMYSARGVMM
EEEECCCCCCCCCCCCEEEEEECEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEEE
LAHNVHDIQVLKRHVHANRLNGIDNEWLSPEQAKEFCPPLNVSRDARYPVVGAALQRRGG
EECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCC
TARHDAVAWGYARGASARGVHIIQNCEVTGVKRAANGAVMGVDTTRGFIGAKKVGVVAAG
CCCCCCEEEECCCCCCCCCEEEEECCCEECEEECCCCCEEEECCCCCCCCCCCEEEEEEC
HSSVIMNMAGVRMPLESYPLQALVSEPVKPVVPCVVMSNTVHAYISQSDKGELVIGAGTD
CHHHHHHHHCCCCCHHHCCHHHHHHCCCCHHHCEEEECCCEEEEEECCCCCCEEEECCCC
QYVSYSQTGGLHILQHTLDAICEMFPIFTRMKMLRSWGGIVDVTPDRSPILAKTPVPGLY
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCEE
VNCGWGTGGFKATPGSGHVFAHTIARDDPHPINAPFTIERFRTGRLIDEAAAAAVAH
EECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKYSVFAIAREAMRGHKGWEEQWSSPEPKKEYDVIIVGAGGHGLATAYYLATVHGITNV
CCCEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEE
AVLEKGWLGGGNTGRNTTIIRSNYLYDESAGIYDHALKLWDGLSQELNYNVMYSARGVMM
EEEECCCCCCCCCCCCEEEEEECEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEEE
LAHNVHDIQVLKRHVHANRLNGIDNEWLSPEQAKEFCPPLNVSRDARYPVVGAALQRRGG
EECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCC
TARHDAVAWGYARGASARGVHIIQNCEVTGVKRAANGAVMGVDTTRGFIGAKKVGVVAAG
CCCCCCEEEECCCCCCCCCEEEEECCCEECEEECCCCCEEEECCCCCCCCCCCEEEEEEC
HSSVIMNMAGVRMPLESYPLQALVSEPVKPVVPCVVMSNTVHAYISQSDKGELVIGAGTD
CHHHHHHHHCCCCCHHHCCHHHHHHCCCCHHHCEEEECCCEEEEEECCCCCCEEEECCCC
QYVSYSQTGGLHILQHTLDAICEMFPIFTRMKMLRSWGGIVDVTPDRSPILAKTPVPGLY
HHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCEE
VNCGWGTGGFKATPGSGHVFAHTIARDDPHPINAPFTIERFRTGRLIDEAAAAAVAH
EECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]