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The map label for this gene is yebQ [C]

Identifier: 13472733

GI number: 13472733

Start: 2506674

End: 2508110

Strand: Direct

Name: yebQ [C]

Synonym: mlr3125

Alternate gene names: 13472733

Gene position: 2506674-2508110 (Clockwise)

Preceding gene: 13472732

Following gene: 13472739

Centisome position: 35.63

GC content: 67.08

Gene sequence:

>1437_bases
ATGACTGAAATCAGCACAAACAGGGTCGACTGGCGGGCATTGTGGGCGAGCGGCGACCTGGCGCGCTTCTGCTTCATCAG
CCTCGGCATCCTGCTGCACGCCACCAACGAGACGATGGTTGCGACCGTCATGCCGGCCATGGTCGGTGAACTGGCCGGGG
TGCAACTCGTCGGCTGGTCATTGGCGATCTACGAGCTCGGCGCCATCGTCGCCGGTGCCGCCGCCGGGCGGCTGGTGAGC
TATGTGGCGCTGCGCACCAATATGGTGGTCGCGGCCCTGCTCTACGCGGCCGGTGCGCTGATCTGCGCCACCTCGCCTTC
CATGCAGTTGTTCCTCGCCGGCCGGCTGATCGAGGGACTGGGCGGTGGCGCGCTGGTGTCGCTCGCCTTCGTCTCGGTCG
AGCGGCTGTTTTCGCGCGCCATCTGGCCGCAGCTCTTCGGCATCATGTCGGCGATCTGGGGCGTCGCGGCGTTCAGCGGC
CCGTTGCTGGGCGCGCTCATGACCGAATTCCTGTCGTGGCGCTGGGCCTTCGGCGTCTTCACCCTCGGCGGCGCCACCAT
GGCGCTGGCCAGCTTCCTCGTGCTCAACACGCCGGAGGCGAAGAAACCCAGCACGAGCGCCGGCAGGACCCCGCCTTTCC
CCTTCGCCGCCCTTGCCTGCCTTGCCGTCGCCGTGGTGCTGATCGCCTCGGCCGGCGTCGACATCGCCTTGCTGCGCTCT
TCGCTGCTGATCGTGCTGGGCCTCGCCGGGCTCGCGCTGTTCTTCTATATCGACGCGCTAAGGCCGCGCTCGCGACTATT
TCCGGCGCGGCTGTTTTCGTGGCGCACGCCGGTCGGCGCCGGGATGACAATGGTCGCCGCCTTTTCCGTCGCGACCTGTT
CCTTCGGCGTCTACGGGCCGCTGCTTTTGACCAGCCTGCACGACATTCCGCTGCTGACCACCGGCTATATCATCGCCGCC
GAATCGATCGCCTGGTCGATCCTGTCGATCCTCGTCGCCAACGCGCCGCCGCAACGTGAACGGCTGATCATTGTCACCGG
TGCGCTCATGATCGCGGCGGGCATCGCCGGCTTTGCCTATACGATACCCCTGGGCTCCATCCCGCTGATCCTGATATGCG
CCTTGCTCCAGGGCGGCGGCTTCGGCATTGCCTGGCCGTTCCTGACCCGCGTCATCGTCGCCTCCGCTCCGGATGACGAG
CAGACCATTGCTTCCGCTGCGGTGCCGACCATGCAGCGCATCGGCTATGCCGTTGGTGCCGCCCTCGCCGGCATCGTCGC
CAATGCCAGCGGTTTTTCGCAAGGGCTGAACCATGACGCGGCGGCCAATGTCGCGAGCTGGCTGTTCCTTGCCTTCGTCC
CGCTTGGCATCCTCGGCTGTCTCGCCGCCTTGCGGACGTCGGCGGCCGCAAACCGGCCGCTGGAAGCCATCGGCTGA

Upstream 100 bases:

>100_bases
CGCTATCCGGCGCTATTGCCGCGCATGGTCCTGCCGGAAAGCCTTGTTGGCTTCTGGTGCCGTGCGCCGGCATCGAGATA
TGCAGAAGCATGGGATGGAC

Downstream 100 bases:

>100_bases
CAAGAGTTCAATCGAGCGCTGTCTCAGTCGACACGCAGCCGATAGCCGACACCGGTCTCGGTAGTGATGTAGCGTGGCTG
GTCGGGGGTCTTCTCGATCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTEISTNRVDWRALWASGDLARFCFISLGILLHATNETMVATVMPAMVGELAGVQLVGWSLAIYELGAIVAGAAAGRLVS
YVALRTNMVVAALLYAAGALICATSPSMQLFLAGRLIEGLGGGALVSLAFVSVERLFSRAIWPQLFGIMSAIWGVAAFSG
PLLGALMTEFLSWRWAFGVFTLGGATMALASFLVLNTPEAKKPSTSAGRTPPFPFAALACLAVAVVLIASAGVDIALLRS
SLLIVLGLAGLALFFYIDALRPRSRLFPARLFSWRTPVGAGMTMVAAFSVATCSFGVYGPLLLTSLHDIPLLTTGYIIAA
ESIAWSILSILVANAPPQRERLIIVTGALMIAAGIAGFAYTIPLGSIPLILICALLQGGGFGIAWPFLTRVIVASAPDDE
QTIASAAVPTMQRIGYAVGAALAGIVANASGFSQGLNHDAAANVASWLFLAFVPLGILGCLAALRTSAAANRPLEAIG

Sequences:

>Translated_478_residues
MTEISTNRVDWRALWASGDLARFCFISLGILLHATNETMVATVMPAMVGELAGVQLVGWSLAIYELGAIVAGAAAGRLVS
YVALRTNMVVAALLYAAGALICATSPSMQLFLAGRLIEGLGGGALVSLAFVSVERLFSRAIWPQLFGIMSAIWGVAAFSG
PLLGALMTEFLSWRWAFGVFTLGGATMALASFLVLNTPEAKKPSTSAGRTPPFPFAALACLAVAVVLIASAGVDIALLRS
SLLIVLGLAGLALFFYIDALRPRSRLFPARLFSWRTPVGAGMTMVAAFSVATCSFGVYGPLLLTSLHDIPLLTTGYIIAA
ESIAWSILSILVANAPPQRERLIIVTGALMIAAGIAGFAYTIPLGSIPLILICALLQGGGFGIAWPFLTRVIVASAPDDE
QTIASAAVPTMQRIGYAVGAALAGIVANASGFSQGLNHDAAANVASWLFLAFVPLGILGCLAALRTSAAANRPLEAIG
>Mature_477_residues
TEISTNRVDWRALWASGDLARFCFISLGILLHATNETMVATVMPAMVGELAGVQLVGWSLAIYELGAIVAGAAAGRLVSY
VALRTNMVVAALLYAAGALICATSPSMQLFLAGRLIEGLGGGALVSLAFVSVERLFSRAIWPQLFGIMSAIWGVAAFSGP
LLGALMTEFLSWRWAFGVFTLGGATMALASFLVLNTPEAKKPSTSAGRTPPFPFAALACLAVAVVLIASAGVDIALLRSS
LLIVLGLAGLALFFYIDALRPRSRLFPARLFSWRTPVGAGMTMVAAFSVATCSFGVYGPLLLTSLHDIPLLTTGYIIAAE
SIAWSILSILVANAPPQRERLIIVTGALMIAAGIAGFAYTIPLGSIPLILICALLQGGGFGIAWPFLTRVIVASAPDDEQ
TIASAAVPTMQRIGYAVGAALAGIVANASGFSQGLNHDAAANVASWLFLAFVPLGILGCLAALRTSAAANRPLEAIG

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322958, Length=202, Percent_Identity=27.7227722772277, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321663, Length=141, Percent_Identity=28.3687943262411, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49557; Mature: 49426

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEISTNRVDWRALWASGDLARFCFISLGILLHATNETMVATVMPAMVGELAGVQLVGWS
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHH
LAIYELGAIVAGAAAGRLVSYVALRTNMVVAALLYAAGALICATSPSMQLFLAGRLIEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHC
GGGALVSLAFVSVERLFSRAIWPQLFGIMSAIWGVAAFSGPLLGALMTEFLSWRWAFGVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TLGGATMALASFLVLNTPEAKKPSTSAGRTPPFPFAALACLAVAVVLIASAGVDIALLRS
HHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
SLLIVLGLAGLALFFYIDALRPRSRLFPARLFSWRTPVGAGMTMVAAFSVATCSFGVYGP
HHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHH
LLLTSLHDIPLLTTGYIIAAESIAWSILSILVANAPPQRERLIIVTGALMIAAGIAGFAY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHE
TIPLGSIPLILICALLQGGGFGIAWPFLTRVIVASAPDDEQTIASAAVPTMQRIGYAVGA
ECCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ALAGIVANASGFSQGLNHDAAANVASWLFLAFVPLGILGCLAALRTSAAANRPLEAIG
HHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure 
TEISTNRVDWRALWASGDLARFCFISLGILLHATNETMVATVMPAMVGELAGVQLVGWS
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHH
LAIYELGAIVAGAAAGRLVSYVALRTNMVVAALLYAAGALICATSPSMQLFLAGRLIEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHC
GGGALVSLAFVSVERLFSRAIWPQLFGIMSAIWGVAAFSGPLLGALMTEFLSWRWAFGVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TLGGATMALASFLVLNTPEAKKPSTSAGRTPPFPFAALACLAVAVVLIASAGVDIALLRS
HHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
SLLIVLGLAGLALFFYIDALRPRSRLFPARLFSWRTPVGAGMTMVAAFSVATCSFGVYGP
HHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHH
LLLTSLHDIPLLTTGYIIAAESIAWSILSILVANAPPQRERLIIVTGALMIAAGIAGFAY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHE
TIPLGSIPLILICALLQGGGFGIAWPFLTRVIVASAPDDEQTIASAAVPTMQRIGYAVGA
ECCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ALAGIVANASGFSQGLNHDAAANVASWLFLAFVPLGILGCLAALRTSAAANRPLEAIG
HHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]