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The map label for this gene is potC [H]

Identifier: 13472603

GI number: 13472603

Start: 2372337

End: 2373134

Strand: Reverse

Name: potC [H]

Synonym: mll2949

Alternate gene names: 13472603

Gene position: 2373134-2372337 (Counterclockwise)

Preceding gene: 13472604

Following gene: 13472602

Centisome position: 33.73

GC content: 64.16

Gene sequence:

>798_bases
ATGGAGATGAAGCCGCTCACGCGCCTGCTTTTGGGCCTGGTCTGCCTGCTGGTGGCGATATGGCTGGTGGCGCCGACGCT
GGTCGTCGTGCCGATGTCGTTCAACGAGAACAAATCGCTCGCGTTTCCGCCGCAAGGCTTCTCCTGGCAATGGTATCAGA
ATTTCGCCACCAGCCCGGAATGGTCCGCGAGTTTTCTCAATTCGCTAAAGGTCGCCTCGGTGGTGGCGGTGCTGGCGACG
GTGCTTGGCACGCTCGCGGCCTTCGGCCTCGACCGCATGAAGGCCGGGCCGGCCGGCCTGTTGCGGATGCTGATGCTGAC
GCCGATGGTGGTGCCGGGCGTGGTGCTGGCCATCGGCATCTACGCCGTCTATCTCGACACCCATCTCGTCGGCACGATGC
TGGGCTTCGTGCTTGCCCACACCATCCTTGCGCTTCCCTTCGTGCTGATCGCGGTCTCGGCCAGTCTCGAAGTGTTCGAC
AGGCGCCTGGAGACGGCGGCAGCGAGCCTCGGCGCGGGAGCGCTGACGGCGTTCCGCACGGTGACGCTGCCACTGATCCT
GCCCGGCATCCTGTCCGGCCTGCTCTTCGCCTTCGCCACCTCCTTCGACGAGATCGTCGTGTCGCTGTTCATCACCAACC
CCTATCTCAAGACCTTGCCCGTGCAGATATTCTCCTCCATCACCCGCGACGCCGATCCGACGGTTGCCGCCGTCGGCACC
ATCCTGCTTTTCGCCACCACGATCCTGATAGGCGGCGGCATGCTTCTTCTCGGTCGCGAGCGGAAAGGACCCCAATGA

Upstream 100 bases:

>100_bases
GCGGCGCGATGGGCGTGGTGCTGCTCGTCGCAACCTTCGTGCTCCTGGCGCTCGCCGCACCGGTGATGCGATCCAGGTAC
CGCGAAGCAGGGCGGCGCTG

Downstream 100 bases:

>100_bases
AGCCTGCACAGGAGAGCAAGGGCGCGGCGATCGATCTCGAATCGATCAGCAAGGCCTATGGCGGCTTCAAGGCGCTGGAC
GGCGTGTCGCTGCGCATCGA

Product: ABC transporter, permease protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MEMKPLTRLLLGLVCLLVAIWLVAPTLVVVPMSFNENKSLAFPPQGFSWQWYQNFATSPEWSASFLNSLKVASVVAVLAT
VLGTLAAFGLDRMKAGPAGLLRMLMLTPMVVPGVVLAIGIYAVYLDTHLVGTMLGFVLAHTILALPFVLIAVSASLEVFD
RRLETAAASLGAGALTAFRTVTLPLILPGILSGLLFAFATSFDEIVVSLFITNPYLKTLPVQIFSSITRDADPTVAAVGT
ILLFATTILIGGGMLLLGRERKGPQ

Sequences:

>Translated_265_residues
MEMKPLTRLLLGLVCLLVAIWLVAPTLVVVPMSFNENKSLAFPPQGFSWQWYQNFATSPEWSASFLNSLKVASVVAVLAT
VLGTLAAFGLDRMKAGPAGLLRMLMLTPMVVPGVVLAIGIYAVYLDTHLVGTMLGFVLAHTILALPFVLIAVSASLEVFD
RRLETAAASLGAGALTAFRTVTLPLILPGILSGLLFAFATSFDEIVVSLFITNPYLKTLPVQIFSSITRDADPTVAAVGT
ILLFATTILIGGGMLLLGRERKGPQ
>Mature_265_residues
MEMKPLTRLLLGLVCLLVAIWLVAPTLVVVPMSFNENKSLAFPPQGFSWQWYQNFATSPEWSASFLNSLKVASVVAVLAT
VLGTLAAFGLDRMKAGPAGLLRMLMLTPMVVPGVVLAIGIYAVYLDTHLVGTMLGFVLAHTILALPFVLIAVSASLEVFD
RRLETAAASLGAGALTAFRTVTLPLILPGILSGLLFAFATSFDEIVVSLFITNPYLKTLPVQIFSSITRDADPTVAAVGT
ILLFATTILIGGGMLLLGRERKGPQ

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=31.6239316239316, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787081, Length=274, Percent_Identity=32.1167883211679, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787714, Length=242, Percent_Identity=31.8181818181818, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786980, Length=228, Percent_Identity=30.7017543859649, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788764, Length=210, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28232; Mature: 28232

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]