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The map label for this gene is qor [H]

Identifier: 13472500

GI number: 13472500

Start: 2258653

End: 2259579

Strand: Direct

Name: qor [H]

Synonym: mlr2819

Alternate gene names: 13472500

Gene position: 2258653-2259579 (Clockwise)

Preceding gene: 13472498

Following gene: 13472503

Centisome position: 32.1

GC content: 66.56

Gene sequence:

>927_bases
ATGCGTGCCGTTATTCAGAATTCCTTCGGCGGACCCGAAATCCTTGTCGTTGCCAACCAGCCCGATCCCGCTCCCAAGGC
CGGTGAAGTGCTGGTCCGCGTCAGGGCGGCCGGCATCAATCCGGTCGATGGCGCCGTGCGCGCCGGCTACTATCCGCTGC
TCGGAGAGCCGCCCTTCATCCTCGGCTGGGATATTTCGGGAACCGTCGAGGCGCTCGGCGCCGGCGTCACCGGCCTCAAG
GTCGGCGATGAGGTGTTCGGCATGCCGCGCTTTCCCAAGCAGGCGGCGGCTTACGCCGAGCTTGCCGTCGTGCCGGCCGA
CGAGGTCGCGCCGAAGCCGAAGGCGGCGGACCATATCCAGGCAGGCGCGTTGCCGCTGGCCGGTCTGACCGCCTGGCAGG
GCCTTGTCCGCCATGGCGCCTTGAAATCGGGCCAGCGCGTGCTGGTGCATGCGGCGGCGGGCGGCGTCGGCCATCTGGCA
GTGCAGATCGCTAAGGCGCGCGGCGCTTATGTCATCGCCACAGCCAGCCCCAACAAGCTCGATTTCGTCCGCAAGCTCAG
CGCCGACGAGGTCATCGACTACACTCAAGGCGATTTTGCCGGCCGGATCAGCGACATCGATCTGGTGCTCGACCCAATCG
GCGGCGAGCACGCCGAACGCTCGCTCAAGGTCATCAGGAATGGCGGCGTGCTGGTGTCCTTGCTGGACCTCAACGAGGCC
ACCAGGGCGCTGGCCAGCGCGCGCGACATCCGTGTCGAGCGCATGTCCGTCGTGCCTGACCGCGAAGGCCTGATGGAGCT
TGGCCGGTTGATCGACGCGAACAAGCTCACCGTTCATGTGGCCAAGAGCTTCCCGCTCGAAGAGTCCGGGGCCGCTCACG
CCTTTCTCGCCACCAAGCCGATCGGCAAGGTGGCGTTGACGGTTTGA

Upstream 100 bases:

>100_bases
TCACTATCCATGGGGTACGTATATATCAAAAAGGTACATACTGGACAAGGTAATATTACTATCCAAATGATAGCGGCACC
AACCAAGCAGGAGAGATACC

Downstream 100 bases:

>100_bases
CCAACAAAGACACGACCTAAAAGCAAAAGGGCGCGGAGTGCCGCGCCCTTTTGTATCTTCAACCCGGACCTAGTGCCGGT
ATTGCTGGATGCGCGTGGTG

Product: oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRAVIQNSFGGPEILVVANQPDPAPKAGEVLVRVRAAGINPVDGAVRAGYYPLLGEPPFILGWDISGTVEALGAGVTGLK
VGDEVFGMPRFPKQAAAYAELAVVPADEVAPKPKAADHIQAGALPLAGLTAWQGLVRHGALKSGQRVLVHAAAGGVGHLA
VQIAKARGAYVIATASPNKLDFVRKLSADEVIDYTQGDFAGRISDIDLVLDPIGGEHAERSLKVIRNGGVLVSLLDLNEA
TRALASARDIRVERMSVVPDREGLMELGRLIDANKLTVHVAKSFPLEESGAAHAFLATKPIGKVALTV

Sequences:

>Translated_308_residues
MRAVIQNSFGGPEILVVANQPDPAPKAGEVLVRVRAAGINPVDGAVRAGYYPLLGEPPFILGWDISGTVEALGAGVTGLK
VGDEVFGMPRFPKQAAAYAELAVVPADEVAPKPKAADHIQAGALPLAGLTAWQGLVRHGALKSGQRVLVHAAAGGVGHLA
VQIAKARGAYVIATASPNKLDFVRKLSADEVIDYTQGDFAGRISDIDLVLDPIGGEHAERSLKVIRNGGVLVSLLDLNEA
TRALASARDIRVERMSVVPDREGLMELGRLIDANKLTVHVAKSFPLEESGAAHAFLATKPIGKVALTV
>Mature_308_residues
MRAVIQNSFGGPEILVVANQPDPAPKAGEVLVRVRAAGINPVDGAVRAGYYPLLGEPPFILGWDISGTVEALGAGVTGLK
VGDEVFGMPRFPKQAAAYAELAVVPADEVAPKPKAADHIQAGALPLAGLTAWQGLVRHGALKSGQRVLVHAAAGGVGHLA
VQIAKARGAYVIATASPNKLDFVRKLSADEVIDYTQGDFAGRISDIDLVLDPIGGEHAERSLKVIRNGGVLVSLLDLNEA
TRALASARDIRVERMSVVPDREGLMELGRLIDANKLTVHVAKSFPLEESGAAHAFLATKPIGKVALTV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=240, Percent_Identity=37.0833333333333, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI194239674, Length=243, Percent_Identity=32.9218106995885, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI13236495, Length=243, Percent_Identity=32.9218106995885, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI22538446, Length=338, Percent_Identity=31.9526627218935, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI22538444, Length=338, Percent_Identity=31.9526627218935, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI194239676, Length=208, Percent_Identity=36.0576923076923, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI24308257, Length=238, Percent_Identity=32.7731092436975, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI18379349, Length=241, Percent_Identity=31.5352697095436, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI28557745, Length=221, Percent_Identity=32.1266968325792, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI67078404, Length=335, Percent_Identity=26.2686567164179, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1790485, Length=315, Percent_Identity=33.015873015873, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17507255, Length=206, Percent_Identity=32.5242718446602, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71987554, Length=270, Percent_Identity=29.2592592592593, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17556000, Length=248, Percent_Identity=29.4354838709677, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=331, Percent_Identity=27.7945619335347, Blast_Score=108, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324486, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581339, Length=310, Percent_Identity=29.3548387096774, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581341, Length=310, Percent_Identity=29.3548387096774, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 32146; Mature: 32146

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVIQNSFGGPEILVVANQPDPAPKAGEVLVRVRAAGINPVDGAVRAGYYPLLGEPPFI
CCCEECCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCEE
LGWDISGTVEALGAGVTGLKVGDEVFGMPRFPKQAAAYAELAVVPADEVAPKPKAADHIQ
EEECCCCHHHHHCCCCCCEEECHHHCCCCCCCHHHHHHHEEEEECHHHCCCCCCCCCHHH
AGALPLAGLTAWQGLVRHGALKSGQRVLVHAAAGGVGHLAVQIAKARGAYVIATASPNKL
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEEECCCCEEEEECCCCHH
DFVRKLSADEVIDYTQGDFAGRISDIDLVLDPIGGEHAERSLKVIRNGGVLVSLLDLNEA
HHHHHCCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHEECCCEEEEEECCCHH
TRALASARDIRVERMSVVPDREGLMELGRLIDANKLTVHVAKSFPLEESGAAHAFLATKP
HHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEECC
IGKVALTV
CCEEEEEC
>Mature Secondary Structure
MRAVIQNSFGGPEILVVANQPDPAPKAGEVLVRVRAAGINPVDGAVRAGYYPLLGEPPFI
CCCEECCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCEE
LGWDISGTVEALGAGVTGLKVGDEVFGMPRFPKQAAAYAELAVVPADEVAPKPKAADHIQ
EEECCCCHHHHHCCCCCCEEECHHHCCCCCCCHHHHHHHEEEEECHHHCCCCCCCCCHHH
AGALPLAGLTAWQGLVRHGALKSGQRVLVHAAAGGVGHLAVQIAKARGAYVIATASPNKL
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEEECCCCEEEEECCCCHH
DFVRKLSADEVIDYTQGDFAGRISDIDLVLDPIGGEHAERSLKVIRNGGVLVSLLDLNEA
HHHHHCCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHEECCCEEEEEECCCHH
TRALASARDIRVERMSVVPDREGLMELGRLIDANKLTVHVAKSFPLEESGAAHAFLATKP
HHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEECC
IGKVALTV
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]