| Definition | Mesorhizobium loti MAFF303099 chromosome, complete genome. |
|---|---|
| Accession | NC_002678 |
| Length | 7,036,071 |
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The map label for this gene is yhdF [H]
Identifier: 13472472
GI number: 13472472
Start: 2232697
End: 2233479
Strand: Direct
Name: yhdF [H]
Synonym: mlr2780
Alternate gene names: 13472472
Gene position: 2232697-2233479 (Clockwise)
Preceding gene: 13472471
Following gene: 13472473
Centisome position: 31.73
GC content: 65.13
Gene sequence:
>783_bases GTGCCAGCCACCAATACGCTCAGCATCCCCGATCTCGCCGGCAAGGCGGTGCTTGTCACCGGCGCCTCGACCGGCATCGG TGCGGCCCTCGCGCTGGCCTATGCCGCACAGAAATCCAAAGTGGCGCTGCACTACAATTCGAGCCAGGAGGCCGCCGAGA AACTCGCCAAGACCATTCGTGACAGCGGCGGCGAGGTGTTCCTCGTCCAGGGCGATTTTTCCGTTCCAGCCGATGTCGAG CGGGTCGTCGAGGACAGCGCCCAGCATTTCGGCCGCCTCGACGGGCTGGTGAACAATGCCGGCGGCATGCTCGGCCGCAT ACCCTATGCCGAACAGACCGAAGCGCATTACGATGCCGTGATGGACCTCAACGCGCGTTCCGTGCTGACCGCCTCGCGCA AGGCGATGCCGTGGCTGAAGAAGCAGGGCGGCTTCATCGTCAATACCTCGTCGATCGCCGCGCGCAACGGGGCCGGCGGC GGCGCCGGCCTCTACGGCTCCGCCAAGGCGTTCGTCTCCAATGTGACGCGTGGCATGGCCAAGGAACTGATCGGCTTCGG CATCCGCGTCAACGCCGTGGCGCCCGGCACGATCCTGACACCCTTCCATGAGCGCTATTCGACCGACGAGCAGATCAAGG GCATGGTCGCGACCATTCCACAGGGTCGGGCCGGCACGGCGGAGGACTGCGTCGGCGCCTATCTATTCCTCTCGTCGAAC CTTTTGAGCGGCTACATCACCGGCCAGGTGATCGAGGTGAACGGCGGCCAGTTGATGCCGTGA
Upstream 100 bases:
>100_bases GAACTGCAAAGCCAGGGCTATGCCTATCTGCGCCCCTGAGGCTTGAACACCGGGGTGGCAAAGGCCTACGAAGGGCGGCG GACATGCCGGAGGAACAACA
Downstream 100 bases:
>100_bases CCGGCTATCTGCATACTGACGGTCCGCATACTCTTGTCGAAGACTTTGAAGGGGAGACAACAGAATGTACGGACTGATCG GCAAGATGCGCGCGTCACGC
Product: 3-ketoacyl-CoA reductase PhaB
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MPATNTLSIPDLAGKAVLVTGASTGIGAALALAYAAQKSKVALHYNSSQEAAEKLAKTIRDSGGEVFLVQGDFSVPADVE RVVEDSAQHFGRLDGLVNNAGGMLGRIPYAEQTEAHYDAVMDLNARSVLTASRKAMPWLKKQGGFIVNTSSIAARNGAGG GAGLYGSAKAFVSNVTRGMAKELIGFGIRVNAVAPGTILTPFHERYSTDEQIKGMVATIPQGRAGTAEDCVGAYLFLSSN LLSGYITGQVIEVNGGQLMP
Sequences:
>Translated_260_residues MPATNTLSIPDLAGKAVLVTGASTGIGAALALAYAAQKSKVALHYNSSQEAAEKLAKTIRDSGGEVFLVQGDFSVPADVE RVVEDSAQHFGRLDGLVNNAGGMLGRIPYAEQTEAHYDAVMDLNARSVLTASRKAMPWLKKQGGFIVNTSSIAARNGAGG GAGLYGSAKAFVSNVTRGMAKELIGFGIRVNAVAPGTILTPFHERYSTDEQIKGMVATIPQGRAGTAEDCVGAYLFLSSN LLSGYITGQVIEVNGGQLMP >Mature_259_residues PATNTLSIPDLAGKAVLVTGASTGIGAALALAYAAQKSKVALHYNSSQEAAEKLAKTIRDSGGEVFLVQGDFSVPADVER VVEDSAQHFGRLDGLVNNAGGMLGRIPYAEQTEAHYDAVMDLNARSVLTASRKAMPWLKKQGGFIVNTSSIAARNGAGGG AGLYGSAKAFVSNVTRGMAKELIGFGIRVNAVAPGTILTPFHERYSTDEQIKGMVATIPQGRAGTAEDCVGAYLFLSSNL LSGYITGQVIEVNGGQLMP
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.5882352941176, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=33.7349397590361, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=30.2788844621514, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=31.6, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI59889578, Length=199, Percent_Identity=31.1557788944724, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=32.8, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=29.6992481203008, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=31.7647058823529, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=29.6482412060301, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28.4, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=31.413612565445, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40254986, Length=194, Percent_Identity=31.4432989690722, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=35.8267716535433, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=33.6065573770492, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=34.7328244274809, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=32, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=32.9268292682927, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=31.0077519379845, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=30.8300395256917, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=29.1497975708502, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI2367365, Length=228, Percent_Identity=29.3859649122807, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=190, Percent_Identity=29.4736842105263, Blast_Score=62, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=36.5019011406844, Blast_Score=127, Evalue=6e-30, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=34.8659003831418, Blast_Score=127, Evalue=8e-30, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=34, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=32.8358208955224, Blast_Score=120, Evalue=7e-28, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=34.9809885931559, Blast_Score=118, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=33.955223880597, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=32.824427480916, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=34.2307692307692, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=34.2205323193916, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=33.5849056603774, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=34.6153846153846, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=32.3529411764706, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=30.8880308880309, Blast_Score=111, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=31.640625, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=31.25, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=31.1538461538462, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=32.8, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=31.2741312741313, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=31.9838056680162, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=30.078125, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.1828793774319, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=29.5719844357977, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=32.0158102766798, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17536025, Length=269, Percent_Identity=28.6245353159851, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=30.5343511450382, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=32.2834645669291, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193207185, Length=144, Percent_Identity=36.8055555555556, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17561272, Length=272, Percent_Identity=30.8823529411765, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17564282, Length=234, Percent_Identity=24.7863247863248, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17507613, Length=213, Percent_Identity=31.4553990610329, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI32563809, Length=213, Percent_Identity=31.4553990610329, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=30.3030303030303, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=206, Percent_Identity=34.9514563106796, Blast_Score=92, Evalue=1e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=206, Percent_Identity=33.9805825242718, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=29.1457286432161, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322226, Length=189, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=9e-12, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=36.4705882352941, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.1269841269841, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=33.4630350194552, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=34.9397590361446, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=32.9457364341085, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=33.1983805668016, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=35.15625, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=33.8582677165354, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI18859837, Length=163, Percent_Identity=31.9018404907975, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=29.3436293436293, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 27007; Mature: 26876
Theoretical pI: Translated: 7.66; Mature: 7.66
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPATNTLSIPDLAGKAVLVTGASTGIGAALALAYAAQKSKVALHYNSSQEAAEKLAKTIR CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH DSGGEVFLVQGDFSVPADVERVVEDSAQHFGRLDGLVNNAGGMLGRIPYAEQTEAHYDAV CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHH MDLNARSVLTASRKAMPWLKKQGGFIVNTSSIAARNGAGGGAGLYGSAKAFVSNVTRGMA HCCCCHHHHHHHHHHCCHHHHCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH KELIGFGIRVNAVAPGTILTPFHERYSTDEQIKGMVATIPQGRAGTAEDCVGAYLFLSSN HHHHHCCEEEEEECCCCEECCHHHHCCCHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHH LLSGYITGQVIEVNGGQLMP HHHHEEEEEEEEECCCCCCC >Mature Secondary Structure PATNTLSIPDLAGKAVLVTGASTGIGAALALAYAAQKSKVALHYNSSQEAAEKLAKTIR CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH DSGGEVFLVQGDFSVPADVERVVEDSAQHFGRLDGLVNNAGGMLGRIPYAEQTEAHYDAV CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHH MDLNARSVLTASRKAMPWLKKQGGFIVNTSSIAARNGAGGGAGLYGSAKAFVSNVTRGMA HCCCCHHHHHHHHHHCCHHHHCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH KELIGFGIRVNAVAPGTILTPFHERYSTDEQIKGMVATIPQGRAGTAEDCVGAYLFLSSN HHHHHCCEEEEEECCCCEECCHHHHCCCHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHH LLSGYITGQVIEVNGGQLMP HHHHEEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9579061; 9384377 [H]