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The map label for this gene is iolG [H]

Identifier: 13472216

GI number: 13472216

Start: 1981509

End: 1982627

Strand: Direct

Name: iolG [H]

Synonym: mlr2436

Alternate gene names: 13472216

Gene position: 1981509-1982627 (Clockwise)

Preceding gene: 13472214

Following gene: 13472217

Centisome position: 28.16

GC content: 64.88

Gene sequence:

>1119_bases
ATGCAGTGCATAAGGGTGGGAGTGATCGGGGCTGGCGGCGTCGCCCAGGTCGAGCACATTCCGAACCTGCTCAAGCTGCA
CCGGCAGTTCAAGATCCTTGGCGTCTACGATCCGTCGCGAAAAGTCCGCGCTTTCGTCGGCGAGGAATTCGGCCTCGAAA
CATTTTCCGATCTCGACGCACTGCTCGCCATGCCGCTTGACGCCGTGGTCATCGCTTCGCCGGATGCGCTGCACCGAGAA
CAGAGCCTCGCCGCCTTTGCCAGGGGCCTGCACGTCTTCTGCGAAAAGCCGCTTTGCTACGGCGCGCAGGACATCGACCA
ACTGATCGCCGCCAGGGATCGCGCCGGAAAAGTGCTCCAGGTCGGCTACATGAAGCGTTTCGACCCGAGCTACGAGGCAG
CTCTGAACATGCTGCCCGGCACGGCGCGGACGCTTCGCTCCGTTTCGGTCGAGGTCAACGATCCCGACGCCTGGCCGTTC
ATCCGGCACGCCTCCACTTGCCGGGGCGACGACGTCGCGGCGGAATTGATTGCCTCGACCGAAGCCAGGCAGCGCGAGCA
GGTCGACCGCGCGGTGCCCGGGCTCGACGATCCCCACGCCTTTCGCGGCTTTGTCGGCGCCTATTCCTCGTCGATCGTGC
ACGACGTCAACGCCGTCCATGGCTTGCTCGATGCGCTCGGCGTCGCCGATGGTGAAATCGTCGGTGCCTCGCTCTTCGCC
AAAGGCGAAGCCGGCCAGGGCACTGTCCGGCTGCTTGACGGGCAGGCATTGTGGACCATGGCTCACATCGCCACTCCGGG
CCTGCCCGATTACCGTGAGCGCATCACGCTCCATTTCGACGACGCCTCGCTCGAGCTGGAATTTCCCTCGCCCTATCTCA
ACCACCAGCCGACGCGGCTGACCATCCGCACCGGCGACGGCCACACGCTTTCCAGCCGCGACATCCGCAGCGGTTATGAA
GAGGCTTTCGTCGAGGAGCTGAAGGGCTTCTGGTCGGCGATCGTCGAGGGCACGGCGGTGCGCAACACGGCCGAGCATGC
GCGCCGCGACATGACGCTGCTGGCTGGACTGACCCGCCACCACCTCGACCAATCGAAGCAATCAGGAGTTCGCCCGTGA

Upstream 100 bases:

>100_bases
CATCTGGTTCCCAAAAATCAATAGAATCTGGTTCTAACAATGGAACCAAAGGAGGCCTACCCTCAAGAAAAAAGCGTTCG
GGTTCAGATGGGGCTGGCCG

Downstream 100 bases:

>100_bases
CGGTTCGCATCGGCATCAATCCGATCACCTGGACCAATGATGACGTGCCGGAACTCGGCGGCGATACGCCGCTCGAAGTG
TGTCTGAGCGAAACCAGACA

Product: NADH-dependent dyhydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MQCIRVGVIGAGGVAQVEHIPNLLKLHRQFKILGVYDPSRKVRAFVGEEFGLETFSDLDALLAMPLDAVVIASPDALHRE
QSLAAFARGLHVFCEKPLCYGAQDIDQLIAARDRAGKVLQVGYMKRFDPSYEAALNMLPGTARTLRSVSVEVNDPDAWPF
IRHASTCRGDDVAAELIASTEARQREQVDRAVPGLDDPHAFRGFVGAYSSSIVHDVNAVHGLLDALGVADGEIVGASLFA
KGEAGQGTVRLLDGQALWTMAHIATPGLPDYRERITLHFDDASLELEFPSPYLNHQPTRLTIRTGDGHTLSSRDIRSGYE
EAFVEELKGFWSAIVEGTAVRNTAEHARRDMTLLAGLTRHHLDQSKQSGVRP

Sequences:

>Translated_372_residues
MQCIRVGVIGAGGVAQVEHIPNLLKLHRQFKILGVYDPSRKVRAFVGEEFGLETFSDLDALLAMPLDAVVIASPDALHRE
QSLAAFARGLHVFCEKPLCYGAQDIDQLIAARDRAGKVLQVGYMKRFDPSYEAALNMLPGTARTLRSVSVEVNDPDAWPF
IRHASTCRGDDVAAELIASTEARQREQVDRAVPGLDDPHAFRGFVGAYSSSIVHDVNAVHGLLDALGVADGEIVGASLFA
KGEAGQGTVRLLDGQALWTMAHIATPGLPDYRERITLHFDDASLELEFPSPYLNHQPTRLTIRTGDGHTLSSRDIRSGYE
EAFVEELKGFWSAIVEGTAVRNTAEHARRDMTLLAGLTRHHLDQSKQSGVRP
>Mature_372_residues
MQCIRVGVIGAGGVAQVEHIPNLLKLHRQFKILGVYDPSRKVRAFVGEEFGLETFSDLDALLAMPLDAVVIASPDALHRE
QSLAAFARGLHVFCEKPLCYGAQDIDQLIAARDRAGKVLQVGYMKRFDPSYEAALNMLPGTARTLRSVSVEVNDPDAWPF
IRHASTCRGDDVAAELIASTEARQREQVDRAVPGLDDPHAFRGFVGAYSSSIVHDVNAVHGLLDALGVADGEIVGASLFA
KGEAGQGTVRLLDGQALWTMAHIATPGLPDYRERITLHFDDASLELEFPSPYLNHQPTRLTIRTGDGHTLSSRDIRSGYE
EAFVEELKGFWSAIVEGTAVRNTAEHARRDMTLLAGLTRHHLDQSKQSGVRP

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=125, Percent_Identity=32, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787307, Length=146, Percent_Identity=30.8219178082192, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 40635; Mature: 40635

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCIRVGVIGAGGVAQVEHIPNLLKLHRQFKILGVYDPSRKVRAFVGEEFGLETFSDLDA
CCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHCCCCHHHHHHH
LLAMPLDAVVIASPDALHREQSLAAFARGLHVFCEKPLCYGAQDIDQLIAARDRAGKVLQ
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEE
VGYMKRFDPSYEAALNMLPGTARTLRSVSVEVNDPDAWPFIRHASTCRGDDVAAELIAST
EHHHHHCCCCHHHHHHCCCCCHHHHHEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHH
EARQREQVDRAVPGLDDPHAFRGFVGAYSSSIVHDVNAVHGLLDALGVADGEIVGASLFA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHEE
KGEAGQGTVRLLDGQALWTMAHIATPGLPDYRERITLHFDDASLELEFPSPYLNHQPTRL
CCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHCEEEEEECCCEEEEECCCCCCCCCCCEE
TIRTGDGHTLSSRDIRSGYEEAFVEELKGFWSAIVEGTAVRNTAEHARRDMTLLAGLTRH
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HLDQSKQSGVRP
HHHHHHHCCCCC
>Mature Secondary Structure
MQCIRVGVIGAGGVAQVEHIPNLLKLHRQFKILGVYDPSRKVRAFVGEEFGLETFSDLDA
CCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHCCCCHHHHHHH
LLAMPLDAVVIASPDALHREQSLAAFARGLHVFCEKPLCYGAQDIDQLIAARDRAGKVLQ
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEE
VGYMKRFDPSYEAALNMLPGTARTLRSVSVEVNDPDAWPFIRHASTCRGDDVAAELIAST
EHHHHHCCCCHHHHHHCCCCCHHHHHEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHH
EARQREQVDRAVPGLDDPHAFRGFVGAYSSSIVHDVNAVHGLLDALGVADGEIVGASLFA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHEE
KGEAGQGTVRLLDGQALWTMAHIATPGLPDYRERITLHFDDASLELEFPSPYLNHQPTRL
CCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHCEEEEEECCCEEEEECCCCCCCCCCCEE
TIRTGDGHTLSSRDIRSGYEEAFVEELKGFWSAIVEGTAVRNTAEHARRDMTLLAGLTRH
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HLDQSKQSGVRP
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA