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The map label for this gene is oprF [H]

Identifier: 13472147

GI number: 13472147

Start: 1896118

End: 1897446

Strand: Direct

Name: oprF [H]

Synonym: mlr2348

Alternate gene names: 13472147

Gene position: 1896118-1897446 (Clockwise)

Preceding gene: 13472146

Following gene: 13472148

Centisome position: 26.95

GC content: 68.1

Gene sequence:

>1329_bases
ATGAGCCGGGATGATCCTTTCGGACTGTCGGAGGATCGCGAACGCACACGCATCAGGCTGGCGGGCGCCGCGCCACGGCC
GATGGCGCCGCTGGCACCGGGCGCGCCGGTCAAAAGGGCGCGCGCCCATCCCAACACGCTCATCAATATCTTCGCGCCAT
TGCTCGAATTCGCGCCGGAGCTCGAAAGCGCGCTGGCGCCGGAGAACCCGGAAGCGATGCGCACGCGCCTGCTAGACGAG
CTGGTTCAGGCGCGCGACGCCGCGATGGCGGCAGGCTCTTCGCTGGAGCGCGCCGACCAGGCGGCCTGGGCCGTGGCGGC
GTTGCTCGACGACCTCGCGCTGAACACGCCATGGGGTGGCGCCAGCGCCTGGCCGCGCCAGCCGCTGGTGGTCATGCTGC
GTGGCGATGTCGATGCCGGTACCCAGTTTTTCACCCGCCTTGACGAGCTGGAGCGCCATCCCAACCGCGACCGCGAGATG
CTGGAGCTTCAGTATTACTGCCTGGCGCTCGGCTTCCGCGGCAAGTACCGGGTGCCCGGCCGCGCCGGCGACCGCTCGCT
CAATGCCGTGCGTGTGGCAGCCGCGCGCTTCCTGCGCAATGCCGACGCCGAGGACGCGCCGCTGTCGCCGAACTGGAAAG
GCGTGATCGCTTCCGACGAGCCGCAGCGCTTCATCGTTCCGATCTGGGTGATGGCACTTGCCGCGGTTGTCGTCGCCGCC
GTCGCTTATATCGGTCTGTCGATGAGCTTGAGCAGCCAGGCGGTCGAACTCTCCGCCCTCGTGCGCACGCTGCCGCCGGC
CTCGCGCGCCGACGTTGCCCGCGCCGCGCCCAAGCAGGATGCGCCCGCACCCGAACCGCCACAGCCGGTCGATTTCGCGC
TGCTGCCCGCATTCAAGGCCGAAGCGCCGGCGAGCCTCAAGGACGCGCTCAGCGGCACTGAGAGCGTCTCGCTGGCCAAG
CTGATCATCCAGTCCTCCAACCCCGAACTCTTCCAGTCTTCGCGGCCGACACTGTCGCAAGGCTATGAACCGCTGATCCA
GTCGATCGCCAAGGTGATCCTCGCCAATCAGGAGCTGATCGGAAACATCACGATCGTCGGCCATACCGACAATGTGCGCC
TGCAAAGGTCCAATCCGCTCGCGAGCAACCAGCGGCTCTCGGAGGCGCGTGCCCAAACCATAGCGGACCTCCTGGTGCAG
GCTGGCGTGCCACAGGAGCGCATCCATTCCGAAGGCCGCGCCGACTCCGATCCGGTCGCCGACAACTCGACGCGCGAGGG
CCGCGCGCTCAACCGGCGCGTCGAGGTCCTGGTCGAAAAGAGGCTCTGA

Upstream 100 bases:

>100_bases
TGGGCCTCGTTGCTCGACGCCCCCGGCTTCGTCATCGGCGTTTCAGGTGTCCTGCCGAGCGAGCCGCAGGTCGACTGCTA
CTCAGTGAACAGGTGAGGCC

Downstream 100 bases:

>100_bases
GATGTTCATCCTGCGCTTCCTCTGGGCGGTCATCACTTCGCGCTTTCTCTGGACGCTGATCGGCATAGCGCTGCTTTCGC
TTTTGATCTGGGTGTTCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSRDDPFGLSEDRERTRIRLAGAAPRPMAPLAPGAPVKRARAHPNTLINIFAPLLEFAPELESALAPENPEAMRTRLLDE
LVQARDAAMAAGSSLERADQAAWAVAALLDDLALNTPWGGASAWPRQPLVVMLRGDVDAGTQFFTRLDELERHPNRDREM
LELQYYCLALGFRGKYRVPGRAGDRSLNAVRVAAARFLRNADAEDAPLSPNWKGVIASDEPQRFIVPIWVMALAAVVVAA
VAYIGLSMSLSSQAVELSALVRTLPPASRADVARAAPKQDAPAPEPPQPVDFALLPAFKAEAPASLKDALSGTESVSLAK
LIIQSSNPELFQSSRPTLSQGYEPLIQSIAKVILANQELIGNITIVGHTDNVRLQRSNPLASNQRLSEARAQTIADLLVQ
AGVPQERIHSEGRADSDPVADNSTREGRALNRRVEVLVEKRL

Sequences:

>Translated_442_residues
MSRDDPFGLSEDRERTRIRLAGAAPRPMAPLAPGAPVKRARAHPNTLINIFAPLLEFAPELESALAPENPEAMRTRLLDE
LVQARDAAMAAGSSLERADQAAWAVAALLDDLALNTPWGGASAWPRQPLVVMLRGDVDAGTQFFTRLDELERHPNRDREM
LELQYYCLALGFRGKYRVPGRAGDRSLNAVRVAAARFLRNADAEDAPLSPNWKGVIASDEPQRFIVPIWVMALAAVVVAA
VAYIGLSMSLSSQAVELSALVRTLPPASRADVARAAPKQDAPAPEPPQPVDFALLPAFKAEAPASLKDALSGTESVSLAK
LIIQSSNPELFQSSRPTLSQGYEPLIQSIAKVILANQELIGNITIVGHTDNVRLQRSNPLASNQRLSEARAQTIADLLVQ
AGVPQERIHSEGRADSDPVADNSTREGRALNRRVEVLVEKRL
>Mature_441_residues
SRDDPFGLSEDRERTRIRLAGAAPRPMAPLAPGAPVKRARAHPNTLINIFAPLLEFAPELESALAPENPEAMRTRLLDEL
VQARDAAMAAGSSLERADQAAWAVAALLDDLALNTPWGGASAWPRQPLVVMLRGDVDAGTQFFTRLDELERHPNRDREML
ELQYYCLALGFRGKYRVPGRAGDRSLNAVRVAAARFLRNADAEDAPLSPNWKGVIASDEPQRFIVPIWVMALAAVVVAAV
AYIGLSMSLSSQAVELSALVRTLPPASRADVARAAPKQDAPAPEPPQPVDFALLPAFKAEAPASLKDALSGTESVSLAKL
IIQSSNPELFQSSRPTLSQGYEPLIQSIAKVILANQELIGNITIVGHTDNVRLQRSNPLASNQRLSEARAQTIADLLVQA
GVPQERIHSEGRADSDPVADNSTREGRALNRRVEVLVEKRL

Specific function: Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium [H]

COG id: COG3455

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=137, Percent_Identity=32.8467153284672, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 47861; Mature: 47730

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRDDPFGLSEDRERTRIRLAGAAPRPMAPLAPGAPVKRARAHPNTLINIFAPLLEFAPE
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHH
LESALAPENPEAMRTRLLDELVQARDAAMAAGSSLERADQAAWAVAALLDDLALNTPWGG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASAWPRQPLVVMLRGDVDAGTQFFTRLDELERHPNRDREMLELQYYCLALGFRGKYRVPG
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECCC
RAGDRSLNAVRVAAARFLRNADAEDAPLSPNWKGVIASDEPQRFIVPIWVMALAAVVVAA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHH
VAYIGLSMSLSSQAVELSALVRTLPPASRADVARAAPKQDAPAPEPPQPVDFALLPAFKA
HHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHC
EAPASLKDALSGTESVSLAKLIIQSSNPELFQSSRPTLSQGYEPLIQSIAKVILANQELI
CCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCCCCHHHCHHHHHHHHHHHHHCCHHHH
GNITIVGHTDNVRLQRSNPLASNQRLSEARAQTIADLLVQAGVPQERIHSEGRADSDPVA
CEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
DNSTREGRALNRRVEVLVEKRL
CCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRDDPFGLSEDRERTRIRLAGAAPRPMAPLAPGAPVKRARAHPNTLINIFAPLLEFAPE
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHH
LESALAPENPEAMRTRLLDELVQARDAAMAAGSSLERADQAAWAVAALLDDLALNTPWGG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASAWPRQPLVVMLRGDVDAGTQFFTRLDELERHPNRDREMLELQYYCLALGFRGKYRVPG
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECCC
RAGDRSLNAVRVAAARFLRNADAEDAPLSPNWKGVIASDEPQRFIVPIWVMALAAVVVAA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHH
VAYIGLSMSLSSQAVELSALVRTLPPASRADVARAAPKQDAPAPEPPQPVDFALLPAFKA
HHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHC
EAPASLKDALSGTESVSLAKLIIQSSNPELFQSSRPTLSQGYEPLIQSIAKVILANQELI
CCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCCCCHHHCHHHHHHHHHHHHHCCHHHH
GNITIVGHTDNVRLQRSNPLASNQRLSEARAQTIADLLVQAGVPQERIHSEGRADSDPVA
CEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
DNSTREGRALNRRVEVLVEKRL
CCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1898935 [H]