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The map label for this gene is gsiC [H]

Identifier: 13472091

GI number: 13472091

Start: 1832841

End: 1833794

Strand: Reverse

Name: gsiC [H]

Synonym: mll2275

Alternate gene names: 13472091

Gene position: 1833794-1832841 (Counterclockwise)

Preceding gene: 13472092

Following gene: 13472090

Centisome position: 26.06

GC content: 69.29

Gene sequence:

>954_bases
ATGGCGCGGCCGCTGGCGGCACGCGCGGGCTCGCTGCTGTTGACGCTGTGGCTGGTCAGCGCGCTGGTCTTCCTCGCCGG
GCAGGTGCTGCCCGGCGATGTCGGCCGCGTCATGCTCGGCCCGTTCGCCGACGCGCAGGCGGTCGCTGAGTTGAACCGCA
AGCTCGGCACCGACCAGCCGATCCCTCAGCAGTACTGGCACTGGTTCAGCCGGGCGATCACGGGCGATTTCGGCGACTCG
CTGTCGATGCGCGCGCCGGTGGCGCCGTTCGTCCTGTCGAGCATCAAGAATTCCTCGGCACTTGCCGGCGTCGTGCTGCT
GTTCCTGGTGCCGATCGGCATCGGCGCCGGCGTCGTCGCAGGCCTGCGCTCGGGGAGCCTTGCCGACAGGCTGATCGTGC
TGACCGGGGTCTCGCTCTCGATCGTGCCCGATTTCGTCTCCGGCCTGCTGTTGCTGATGGTCTTCGGCCTGTGGCTGGCC
TGGTTTCCGATCACCGGTGCTGCGCCCAACGGGGCCGGCTTCTGGACGGCCAGCCACTATCTCATTCTGCCGGCGCTGCC
GCTGGTGCTGAACCTGATCGGCTACGTCGCGCGCATGACCAGGGCCGGGGTGATCGAGGCGCGCGCGGCGGACTATACGC
GCACCGCGATCCTGAAGGGGCTCAGCCCCGCGCAGGTGCTGTTCAAGCACGTGCTGCGCAACGCGCTGGTGCCGACGGTG
GCGGTCATCGCCACGCAGAGCGGCTTCCTGCTCGGCGGGCTGGTGGTGATCGAGGCGTTGTTCGGCATACAGGGTCTCGG
CAATCTGGTGCTGAGCGCGGCCAAGGCGCGCGACTTCCCGATGCTCGAGGCCGGCGTGCTGGTGATGGCTGCGATTTTCG
TGTCGACGGCCGCGATCGGCGATCTCCTGCAGGCGCTGCTCGACCCGCGCCAGCGCCGGAGCAACGCCCCATGA

Upstream 100 bases:

>100_bases
ACAGCCGCATCGTCTCCGCGAAGGTCGAGGGCGTGCGCTTCACCGCCATCTCGCATCTGCTGCTCGACAAGGTGTCGTTC
GTGTGAGCGGCATCGCCTCG

Downstream 100 bases:

>100_bases
CCGAACTCGCCCAGTCCCCCATGCGCAGTGAAATCCGGCTCTCCTGGATCGGCCGGCTGCGCGGTCTTTTGCCCGATGTG
GCGCCGTCGACCGTAGTCGG

Product: permease protein of oligopeptide ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MARPLAARAGSLLLTLWLVSALVFLAGQVLPGDVGRVMLGPFADAQAVAELNRKLGTDQPIPQQYWHWFSRAITGDFGDS
LSMRAPVAPFVLSSIKNSSALAGVVLLFLVPIGIGAGVVAGLRSGSLADRLIVLTGVSLSIVPDFVSGLLLLMVFGLWLA
WFPITGAAPNGAGFWTASHYLILPALPLVLNLIGYVARMTRAGVIEARAADYTRTAILKGLSPAQVLFKHVLRNALVPTV
AVIATQSGFLLGGLVVIEALFGIQGLGNLVLSAAKARDFPMLEAGVLVMAAIFVSTAAIGDLLQALLDPRQRRSNAP

Sequences:

>Translated_317_residues
MARPLAARAGSLLLTLWLVSALVFLAGQVLPGDVGRVMLGPFADAQAVAELNRKLGTDQPIPQQYWHWFSRAITGDFGDS
LSMRAPVAPFVLSSIKNSSALAGVVLLFLVPIGIGAGVVAGLRSGSLADRLIVLTGVSLSIVPDFVSGLLLLMVFGLWLA
WFPITGAAPNGAGFWTASHYLILPALPLVLNLIGYVARMTRAGVIEARAADYTRTAILKGLSPAQVLFKHVLRNALVPTV
AVIATQSGFLLGGLVVIEALFGIQGLGNLVLSAAKARDFPMLEAGVLVMAAIFVSTAAIGDLLQALLDPRQRRSNAP
>Mature_316_residues
ARPLAARAGSLLLTLWLVSALVFLAGQVLPGDVGRVMLGPFADAQAVAELNRKLGTDQPIPQQYWHWFSRAITGDFGDSL
SMRAPVAPFVLSSIKNSSALAGVVLLFLVPIGIGAGVVAGLRSGSLADRLIVLTGVSLSIVPDFVSGLLLLMVFGLWLAW
FPITGAAPNGAGFWTASHYLILPALPLVLNLIGYVARMTRAGVIEARAADYTRTAILKGLSPAQVLFKHVLRNALVPTVA
VIATQSGFLLGGLVVIEALFGIQGLGNLVLSAAKARDFPMLEAGVLVMAAIFVSTAAIGDLLQALLDPRQRRSNAP

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=301, Percent_Identity=38.8704318936877, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=31.2684365781711, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789888, Length=273, Percent_Identity=32.967032967033, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787497, Length=301, Percent_Identity=29.9003322259136, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=29.6969696969697, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1788504, Length=281, Percent_Identity=28.4697508896797, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=27.8388278388278, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33248; Mature: 33117

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPLAARAGSLLLTLWLVSALVFLAGQVLPGDVGRVMLGPFADAQAVAELNRKLGTDQP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCC
IPQQYWHWFSRAITGDFGDSLSMRAPVAPFVLSSIKNSSALAGVVLLFLVPIGIGAGVVA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GLRSGSLADRLIVLTGVSLSIVPDFVSGLLLLMVFGLWLAWFPITGAAPNGAGFWTASHY
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHH
LILPALPLVLNLIGYVARMTRAGVIEARAADYTRTAILKGLSPAQVLFKHVLRNALVPTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVIATQSGFLLGGLVVIEALFGIQGLGNLVLSAAKARDFPMLEAGVLVMAAIFVSTAAIG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DLLQALLDPRQRRSNAP
HHHHHHHCHHHHCCCCC
>Mature Secondary Structure 
ARPLAARAGSLLLTLWLVSALVFLAGQVLPGDVGRVMLGPFADAQAVAELNRKLGTDQP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCC
IPQQYWHWFSRAITGDFGDSLSMRAPVAPFVLSSIKNSSALAGVVLLFLVPIGIGAGVVA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GLRSGSLADRLIVLTGVSLSIVPDFVSGLLLLMVFGLWLAWFPITGAAPNGAGFWTASHY
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHH
LILPALPLVLNLIGYVARMTRAGVIEARAADYTRTAILKGLSPAQVLFKHVLRNALVPTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVIATQSGFLLGGLVVIEALFGIQGLGNLVLSAAKARDFPMLEAGVLVMAAIFVSTAAIG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DLLQALLDPRQRRSNAP
HHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]