Click here to switch to the map view.

The map label for this gene is yafC [C]

Identifier: 13471829

GI number: 13471829

Start: 1586550

End: 1587443

Strand: Direct

Name: yafC [C]

Synonym: mlr1930

Alternate gene names: 13471829

Gene position: 1586550-1587443 (Clockwise)

Preceding gene: 13471827

Following gene: 13471834

Centisome position: 22.55

GC content: 69.91

Gene sequence:

>894_bases
ATGGCGGCCTTCGCGGCCATCGCCGAGGCGCGCTCCTTCACTAGGGCAGCAGTGCGTGTCGGGCGCGACGCGACCATCCT
GTCGCGGCGCCTGCAATCGCTGGAGGAGCGGCTGGGGGTCAGGCTGCTGCACCGCACGACACGCAGCGTATCGCTGACCG
AAGCGGGTGCCGAATTCCTGGTACGCGTGCGCGCCATCCTCGCCTCCGTCGACGAAGCCGAGGCCGCCGCGTCGGCGCAT
GCCGACGGCAGCCCGCGCGGCCTGCTCAGGCTGGCGCTGCCTGGCACGTTCGGGCGCATGTGGATCGGACCGCTGCTGCC
GCAATTCCTTGCCGAATTTCCCGATATCCGCATCGAGGCCGAATTCTCCAACCGCTTCGCCGATCTGGTCGCCGAGAATT
TCGACGTTGCCGTGCGGCTCGGCGCGCTTGAGGATTCGCGCCTTGTGGCGCGCAAGGTGGCGACGCGGCGCCGGCTGCTT
TGCGCCGCCCCCGCCTATCTCGCCCGAAGAGGCAGGCCGGATACGCCGCAGGCGCTGCTCGAACATTCCTGCCTGGGCTT
CAGCGGCTTCCAGACCTTTCCGGCCTGGGAGATGACCGACCGCGAGGGCCGGCGGGCGCGCGTCGAGGTTTCCGGGCCGT
TGGTCAGCGACGACGCCGAGGTGCTGGTCGAGGCCGCCGTGCAGGGGCTCGGCCTGATGATGAGCACCGACTGGCTGATC
GGCCGCGAACTCGCCGACGGGCGGCTAGTGCCTGTCCTGGAGGAATGGACGCTGGCCGACGAAGGCGCCGTCTATGTCGT
CTTGCCCTCGGCCAAGGGACAAGCCGCCAAGACCCGCGCCTTCGCCGACTGGATCAGCAAGCGCTTCGCGCCGGAGCCGC
CCTGGCGGCAATGA

Upstream 100 bases:

>100_bases
GTGAACCTATCTGCTGCGCTATTTCTGGATAATCATTCCATTTTGCATTTGAGTAATGCCAGATATGCAGCAATCTCACG
AACCGGCGGCCCTTGCCGAA

Downstream 100 bases:

>100_bases
AGTGCCGTCATCCGGTTTTCGCCAAACTCCCCACCTATCCTGGAAAATCCCAGTTCGACCGGTTCAGGACATCGCTGGGT
GGAAGAATCTCTTCGGGCTT

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAAFAAIAEARSFTRAAVRVGRDATILSRRLQSLEERLGVRLLHRTTRSVSLTEAGAEFLVRVRAILASVDEAEAAASAH
ADGSPRGLLRLALPGTFGRMWIGPLLPQFLAEFPDIRIEAEFSNRFADLVAENFDVAVRLGALEDSRLVARKVATRRRLL
CAAPAYLARRGRPDTPQALLEHSCLGFSGFQTFPAWEMTDREGRRARVEVSGPLVSDDAEVLVEAAVQGLGLMMSTDWLI
GRELADGRLVPVLEEWTLADEGAVYVVLPSAKGQAAKTRAFADWISKRFAPEPPWRQ

Sequences:

>Translated_297_residues
MAAFAAIAEARSFTRAAVRVGRDATILSRRLQSLEERLGVRLLHRTTRSVSLTEAGAEFLVRVRAILASVDEAEAAASAH
ADGSPRGLLRLALPGTFGRMWIGPLLPQFLAEFPDIRIEAEFSNRFADLVAENFDVAVRLGALEDSRLVARKVATRRRLL
CAAPAYLARRGRPDTPQALLEHSCLGFSGFQTFPAWEMTDREGRRARVEVSGPLVSDDAEVLVEAAVQGLGLMMSTDWLI
GRELADGRLVPVLEEWTLADEGAVYVVLPSAKGQAAKTRAFADWISKRFAPEPPWRQ
>Mature_296_residues
AAFAAIAEARSFTRAAVRVGRDATILSRRLQSLEERLGVRLLHRTTRSVSLTEAGAEFLVRVRAILASVDEAEAAASAHA
DGSPRGLLRLALPGTFGRMWIGPLLPQFLAEFPDIRIEAEFSNRFADLVAENFDVAVRLGALEDSRLVARKVATRRRLLC
AAPAYLARRGRPDTPQALLEHSCLGFSGFQTFPAWEMTDREGRRARVEVSGPLVSDDAEVLVEAAVQGLGLMMSTDWLIG
RELADGRLVPVLEEWTLADEGAVYVVLPSAKGQAAKTRAFADWISKRFAPEPPWRQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=33.1058020477816, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=31.3793103448276, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=28.4280936454849, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=31.7567567567568, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=30.8474576271186, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=29.1666666666667, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=29.553264604811, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789173, Length=290, Percent_Identity=28.9655172413793, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786448, Length=288, Percent_Identity=25.3472222222222, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=28.2229965156794, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=23.6486486486486, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=166, Percent_Identity=32.5301204819277, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32589; Mature: 32458

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFAAIAEARSFTRAAVRVGRDATILSRRLQSLEERLGVRLLHRTTRSVSLTEAGAEFL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VRVRAILASVDEAEAAASAHADGSPRGLLRLALPGTFGRMWIGPLLPQFLAEFPDIRIEA
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEE
EFSNRFADLVAENFDVAVRLGALEDSRLVARKVATRRRLLCAAPAYLARRGRPDTPQALL
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHH
EHSCLGFSGFQTFPAWEMTDREGRRARVEVSGPLVSDDAEVLVEAAVQGLGLMMSTDWLI
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHCCHHEECCHHH
GRELADGRLVPVLEEWTLADEGAVYVVLPSAKGQAAKTRAFADWISKRFAPEPPWRQ
HHHCCCCCEEEHHHHCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AAFAAIAEARSFTRAAVRVGRDATILSRRLQSLEERLGVRLLHRTTRSVSLTEAGAEFL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VRVRAILASVDEAEAAASAHADGSPRGLLRLALPGTFGRMWIGPLLPQFLAEFPDIRIEA
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEE
EFSNRFADLVAENFDVAVRLGALEDSRLVARKVATRRRLLCAAPAYLARRGRPDTPQALL
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHH
EHSCLGFSGFQTFPAWEMTDREGRRARVEVSGPLVSDDAEVLVEAAVQGLGLMMSTDWLI
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHCCHHEECCHHH
GRELADGRLVPVLEEWTLADEGAVYVVLPSAKGQAAKTRAFADWISKRFAPEPPWRQ
HHHCCCCCEEEHHHHCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]