Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 13471733

GI number: 13471733

Start: 1490165

End: 1491169

Strand: Direct

Name: yccK [H]

Synonym: mlr1801

Alternate gene names: 13471733

Gene position: 1490165-1491169 (Clockwise)

Preceding gene: 13471732

Following gene: 13471735

Centisome position: 21.18

GC content: 65.97

Gene sequence:

>1005_bases
ATGACCCTCGCGACACGAAAACTCGGCAGCCAGGGATTGACAGTCTCGGCCATCGGCCTCGGCTGCATGGGCATGAGCCA
GTCTTACGGCCCGGCCGACGAGGCCGAGTCCATCGCCACGCTGCATCGCGCCATCGAACTTGGCTGCACCTTCCTGGATA
CCGCCGAGGTCTATGGCCCGCACACCAACGAGGCATTGCTCGGCCGGGCACTGAAGGGCAAACGCGATCAGGTGACGATC
GCCACCAAATTCGGCTTCCGCATCGAAAACGGCAAGCAGCTCAGCGGGGTCGATAGCCGGCCCGAGCATATCCGCGAGGT
TGTCGAAGCCTCGCTCGGCCGGCTCGCCACCGACCATATCGACCTGCTCTACCAGCACCGTGTCGACCCTGATGTGCCGA
TGGAGGATGTCGCCGGCGCGGTCGGCAAGCTTGTGGCCGAGGGCAAGGTGCGCTTTTTCGGCCTGTCGGAGGCCGGTAGC
GCCAACATCCGCCGGGCGCATGCCGTCTTCCCCGTCTCGGCGCTGCAGAGCGAATATTCGCTGTGGGAGCGCAATCTGGA
GCCGGAGATCATCCCGCTGCTCAAGGAACTCGGCATCGGCCTGGTGCCCTTCTCGCCGCTCGGCCGCGGCTTTCTCACCG
GCGATGTCAAGCGCGCCGAGGATTACCCCGAAGGCGACTACCGCCGCAACGACCCGCGCTACCAGGGCGAGAATTACGAC
GCCAATGTCGAGGCCGCCGGCACGGTGCGCGCCATCGCAGCTGCCCGGGGCGTCAAGCCAGGGCAGATCGCGCTGGCATG
GCTGCTCGGCAAGGGCATTGGCTTCGGCATGGATATCGTGCCGATCCCCGGCACCAAGCGCAGAAAATATCTGGAGGAGA
ATGTCGCCGCCGCCTCGCTGAAACTCGACGCCGCCGAAATGGCCGCGCTGGACGAGGCGCTGGCGCCGGAAAAGATCTCC
GGCCCGCGCTACGGCGAACGGGGGATGGCGATGGTGGATCGGTAG

Upstream 100 bases:

>100_bases
CGCCCCATGATCACAGTCCGTTGAGGCGGCGCTGGACACCTATGGCAACCGAGCGCACGCCCTATATGGTGCTGCAAACC
CCAAGCGGAGCAGCGCAGCC

Downstream 100 bases:

>100_bases
CGCTTGGAGCCGCGATCAGGGCGCGTGCTGTCGATCGTCAAACTCAATTGCGAATACCGAAACATGTTCGGCCGACATCA
GCGCCGGCTCGTTTTTGCCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTLATRKLGSQGLTVSAIGLGCMGMSQSYGPADEAESIATLHRAIELGCTFLDTAEVYGPHTNEALLGRALKGKRDQVTI
ATKFGFRIENGKQLSGVDSRPEHIREVVEASLGRLATDHIDLLYQHRVDPDVPMEDVAGAVGKLVAEGKVRFFGLSEAGS
ANIRRAHAVFPVSALQSEYSLWERNLEPEIIPLLKELGIGLVPFSPLGRGFLTGDVKRAEDYPEGDYRRNDPRYQGENYD
ANVEAAGTVRAIAAARGVKPGQIALAWLLGKGIGFGMDIVPIPGTKRRKYLEENVAAASLKLDAAEMAALDEALAPEKIS
GPRYGERGMAMVDR

Sequences:

>Translated_334_residues
MTLATRKLGSQGLTVSAIGLGCMGMSQSYGPADEAESIATLHRAIELGCTFLDTAEVYGPHTNEALLGRALKGKRDQVTI
ATKFGFRIENGKQLSGVDSRPEHIREVVEASLGRLATDHIDLLYQHRVDPDVPMEDVAGAVGKLVAEGKVRFFGLSEAGS
ANIRRAHAVFPVSALQSEYSLWERNLEPEIIPLLKELGIGLVPFSPLGRGFLTGDVKRAEDYPEGDYRRNDPRYQGENYD
ANVEAAGTVRAIAAARGVKPGQIALAWLLGKGIGFGMDIVPIPGTKRRKYLEENVAAASLKLDAAEMAALDEALAPEKIS
GPRYGERGMAMVDR
>Mature_333_residues
TLATRKLGSQGLTVSAIGLGCMGMSQSYGPADEAESIATLHRAIELGCTFLDTAEVYGPHTNEALLGRALKGKRDQVTIA
TKFGFRIENGKQLSGVDSRPEHIREVVEASLGRLATDHIDLLYQHRVDPDVPMEDVAGAVGKLVAEGKVRFFGLSEAGSA
NIRRAHAVFPVSALQSEYSLWERNLEPEIIPLLKELGIGLVPFSPLGRGFLTGDVKRAEDYPEGDYRRNDPRYQGENYDA
NVEAAGTVRAIAAARGVKPGQIALAWLLGKGIGFGMDIVPIPGTKRRKYLEENVAAASLKLDAAEMAALDEALAPEKISG
PRYGERGMAMVDR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=280, Percent_Identity=30.3571428571429, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI27436962, Length=285, Percent_Identity=29.8245614035088, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI27436969, Length=346, Percent_Identity=29.4797687861272, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4504825, Length=346, Percent_Identity=29.4797687861272, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI27436966, Length=282, Percent_Identity=29.7872340425532, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436964, Length=282, Percent_Identity=29.7872340425532, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI223718702, Length=334, Percent_Identity=28.7425149700599, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI41327764, Length=306, Percent_Identity=28.1045751633987, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI41152114, Length=332, Percent_Identity=28.0120481927711, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081735, Length=332, Percent_Identity=31.3253012048193, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=32.6219512195122, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=30.03003003003, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787674, Length=322, Percent_Identity=29.5031055900621, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788081, Length=306, Percent_Identity=25.8169934640523, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789199, Length=306, Percent_Identity=28.1045751633987, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994888, Length=195, Percent_Identity=32.3076923076923, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=348, Percent_Identity=27.8735632183908, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=334, Percent_Identity=25.748502994012, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=26.3843648208469, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=262, Percent_Identity=27.8625954198473, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325384, Length=333, Percent_Identity=25.8258258258258, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=296, Percent_Identity=27.7027027027027, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24640980, Length=297, Percent_Identity=26.2626262626263, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45549126, Length=300, Percent_Identity=26, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24646155, Length=315, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646159, Length=220, Percent_Identity=30.4545454545455, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36014; Mature: 35882

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLATRKLGSQGLTVSAIGLGCMGMSQSYGPADEAESIATLHRAIELGCTFLDTAEVYGP
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEHHHHCCC
HTNEALLGRALKGKRDQVTIATKFGFRIENGKQLSGVDSRPEHIREVVEASLGRLATDHI
CCCHHHHHHHHCCCCCEEEEEEEECEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHH
DLLYQHRVDPDVPMEDVAGAVGKLVAEGKVRFFGLSEAGSANIRRAHAVFPVSALQSEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHH
LWERNLEPEIIPLLKELGIGLVPFSPLGRGFLTGDVKRAEDYPEGDYRRNDPRYQGENYD
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
ANVEAAGTVRAIAAARGVKPGQIALAWLLGKGIGFGMDIVPIPGTKRRKYLEENVAAASL
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHE
KLDAAEMAALDEALAPEKISGPRYGERGMAMVDR
ECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLATRKLGSQGLTVSAIGLGCMGMSQSYGPADEAESIATLHRAIELGCTFLDTAEVYGP
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEHHHHCCC
HTNEALLGRALKGKRDQVTIATKFGFRIENGKQLSGVDSRPEHIREVVEASLGRLATDHI
CCCHHHHHHHHCCCCCEEEEEEEECEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHH
DLLYQHRVDPDVPMEDVAGAVGKLVAEGKVRFFGLSEAGSANIRRAHAVFPVSALQSEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHH
LWERNLEPEIIPLLKELGIGLVPFSPLGRGFLTGDVKRAEDYPEGDYRRNDPRYQGENYD
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
ANVEAAGTVRAIAAARGVKPGQIALAWLLGKGIGFGMDIVPIPGTKRRKYLEENVAAASL
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHE
KLDAAEMAALDEALAPEKISGPRYGERGMAMVDR
ECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]